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Kumar Ganesan
Hong Kong Baptist University
17Publications
4H-index
79Citations
Publications 17
Newest
Published on Jul 13, 2019in Molecules3.06
Kumar Ganesan4
Estimated H-index: 4
,
Baojun Xu29
Estimated H-index: 29
Diabetes mellitus is a multifactorial, heterogeneous metabolic disorder, causing various health complications and economic issues, which apparently impacts the human’s life. Currently, commercial diabetic drugs are clinically managed for diabetic treatment that has definite side effects. Dietary polysaccharides mainly derive from natural sources, including medicinal plants, grains, fruits, vegetables, edible mushroom, and medicinal foods, and possess anti-diabetic potential. Hence, this review s...
Published on Apr 1, 2019in Chemico-Biological Interactions3.41
Muthukumaran Jayachandran4
Estimated H-index: 4
(Hong Kong Baptist University),
Ziyuan Wu (Hong Kong Baptist University)+ 3 AuthorsBaojun Xu29
Estimated H-index: 29
(Hong Kong Baptist University)
Abstract Lifestyle and genetic factors contribute to the initiation of oxidative stress and inflammation in diabetes mellitus (DM). Oxidative stress and lipid peroxidation worked in an orchestrated manner and reported to be strongly associated with the formation of the hyperlipidemic condition in DM patients. Isoquercetin, a bioactive constituent isolated from guava leaves has attracted considerable attention because of its antidiabetic activity. The antidiabetic activity of guava leaves may be ...
Published on Feb 4, 2019in Critical Reviews in Food Science and Nutrition6.70
Kumar Ganesan4
Estimated H-index: 4
(Hong Kong Baptist University),
Kumeshini Sukalingam3
Estimated H-index: 3
(Hong Kong Baptist University),
Baojun Xu29
Estimated H-index: 29
(Hong Kong Baptist University)
ABSTRACTRepeated heating of vegetable oils at high temperatures during cooking is a very common cooking practice. Repeatedly heated cooking oils (RCO) can generate varieties of compounds, including polycyclic aromatic hydrocarbons (PAH), some of which have been reported as carcinogenic. RCO is one of the commonly consumed cooking and frying medium. These RCO consumption and inhalation of cooking fumes can pose a serious health hazard. Taking into account exploratory study, the present review aim...
Published on Nov 22, 2018in International Journal of Molecular Sciences4.18
Kumar Ganesan (Hong Kong Baptist University), Sookja K. Chung36
Estimated H-index: 36
(Hong Kong Baptist University)
+ 1 AuthorsBaojun Xu29
Estimated H-index: 29
(Hong Kong Baptist University)
The incidence of metabolic disorders, including diabetes, has elevated exponentially during the last decades and enhanced the risk of a variety of complications, such as diabetes and cardiovascular diseases. In the present review, we have highlighted the new insights on the complex relationships between diet-induced modulation of gut microbiota and metabolic disorders, including diabetes. Literature from various library databases and electronic searches (ScienceDirect, PubMed, and Google Scholar...
Published on Nov 9, 2018in Frontiers in Pharmacology3.85
Tongze Zhang1
Estimated H-index: 1
(Hong Kong Baptist University),
Tongze Zhang (Hong Kong Baptist University)+ 1 AuthorsBaojun Xu29
Estimated H-index: 29
(Hong Kong Baptist University)
Background and purpose: Tuber melanosporum (black truffle) has been considered as a medicinal mushroom for a long time. T. melanosporum has the ability to attenuate oxidative stress and in turn diabetes mellitus (DM). DM has become an awfully common chronic unwellness, threatening people’s well-being. There are nearly 1 in 10 people in the world affected by diabetes. Oxidative stress plays a crucial role in vascular complications related to DM. Our study aimed to attain an effective treatment me...
Published on Nov 5, 2018in Molecules3.06
Kumar Ganesan4
Estimated H-index: 4
,
Baojun Xu29
Estimated H-index: 29
Obesity is a group of metabolic disorders caused by multiple factors, including heredity, diet, lifestyle, societal determinants, environment, and infectious agents, which can all lead to the enhancement of storage body fat. Excess visceral fat mass in adipose tissue generate several metabolic disorders, including cardiovascular diseases with chronic inflammation based pathophysiology. The objective of the current review is to summarize the cellular mechanisms of obesity that attenuate by antiox...
Published on Jun 22, 2018in Antioxidants
Kumeshini Sukalingam3
Estimated H-index: 3
,
Kumar Ganesan4
Estimated H-index: 4
,
Baojun Xu29
Estimated H-index: 29
The present study aims to examine the protective effect of Justicia tranquebariesis on thioacetamide (TAA)-induced oxidative stress and hepatic fibrosis. Male Wister albino rats (150–200 g) were divided into five groups. Group 1 was normal control. Group 2 was J. tranquebariensis (400 mg/kg bw/p.o.)-treated control. Group 3 was TAA (100 mg/kg bw/s.c.)-treated control. Groups 4 and 5 were orally administered with the leaf extract of J. tranquebariensis (400 mg/kg bw) and silymarin (50 mg/kg bw) d...
Published on Jun 1, 2018in European Journal of Pharmacology3.17
Muthukumaran Jayachandran4
Estimated H-index: 4
(Hong Kong Baptist University),
Tongze Zhang1
Estimated H-index: 1
(Hong Kong Baptist University)
+ 2 AuthorsStephen Sum Man Chung3
Estimated H-index: 3
(Hong Kong Baptist University)
Abstract Among the foremost common flavonoids within the human diet, quercetin glycosides possess neuroprotective, cardioprotective, anti-oxidative, chemopreventive, and anti-allergic properties. Isoquercetin is one such promising candidate with anti-diabetic potential. However, complete studies of its molecular action on insulin signaling pathway and carbohydrate metabolizing enzymes remain unclear. Hence, we have designed this study to accumulate the experimental evidence in support of anti-di...
Published on May 3, 2018in Critical Reviews in Food Science and Nutrition6.70
Kumar Ganesan4
Estimated H-index: 4
(Hong Kong Baptist University),
Muthukumaran Jayachandran4
Estimated H-index: 4
(Hong Kong Baptist University),
Baojun Xu29
Estimated H-index: 29
(Hong Kong Baptist University)
ABSTRACTBackground: Bioactive food components are nonessential biomolecules, which help to give beneficial effects to human being against several diseases. Natural bioactive food components derived from plants and animals, such as phytosterols, carotenoids, polyphenols and fatty acids, have been proposed as valuable substitutions for anticipation and management of hepatotoxic effects and its chronic complications based on in vitro and in vivo studies.Objectives of the study: To summarize drugs a...
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