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Kumar Ganesan
Hong Kong Baptist University
ChemistryAntioxidantBiochemistryBiologyPharmacology
25Publications
7H-index
153Citations
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Publications 27
Newest
#1Kumar GanesanH-Index: 7
Last. Baojun XuH-Index: 30
view all 5 authors...
Colorectal patients generally have the maximum counts of Fusobacterium nucleatum (F. nucleatum) in tumors and elevate colorectal adenomas and carcinomas, which show the lowest rate of human survival. Hence, F. nucleatum is a diagnostic marker of colorectal cancer (CRC). Studies demonstrated that targeting fusobacterial Fap2 or polysaccharide of the host epithelium may decrease fusobacteria count in the CRC. Attenuated F. nucleatum-Fap2 prevents transmembrane signals and inhibits tumorigenesis in...
2 CitationsSource
Diabetes mellitus is a multifactorial, heterogeneous metabolic disorder, causing various health complications and economic issues, which apparently impacts the human’s life. Currently, commercial diabetic drugs are clinically managed for diabetic treatment that has definite side effects. Dietary polysaccharides mainly derive from natural sources, including medicinal plants, grains, fruits, vegetables, edible mushroom, and medicinal foods, and possess anti-diabetic potential. Hence, this review s...
Source
#1Muthukumaran Jayachandran (Hong Kong Baptist University)H-Index: 7
#2Ziyuan Wu (Hong Kong Baptist University)H-Index: 1
Last. Baojun Xu (Hong Kong Baptist University)H-Index: 30
view all 6 authors...
Abstract Lifestyle and genetic factors contribute to the initiation of oxidative stress and inflammation in diabetes mellitus (DM). Oxidative stress and lipid peroxidation worked in an orchestrated manner and reported to be strongly associated with the formation of the hyperlipidemic condition in DM patients. Isoquercetin, a bioactive constituent isolated from guava leaves has attracted considerable attention because of its antidiabetic activity. The antidiabetic activity of guava leaves may be ...
1 CitationsSource
#1Kumar Ganesan (Hong Kong Baptist University)H-Index: 7
#2Kumeshini Sukalingam (Hong Kong Baptist University)H-Index: 3
Last. Baojun Xu (Hong Kong Baptist University)H-Index: 30
view all 3 authors...
ABSTRACTRepeated heating of vegetable oils at high temperatures during cooking is a very common cooking practice. Repeatedly heated cooking oils (RCO) can generate varieties of compounds, including polycyclic aromatic hydrocarbons (PAH), some of which have been reported as carcinogenic. RCO is one of the commonly consumed cooking and frying medium. These RCO consumption and inhalation of cooking fumes can pose a serious health hazard. Taking into account exploratory study, the present review aim...
3 CitationsSource
#1Tahidul Islam (Hong Kong Baptist University)H-Index: 2
#2Kumar Ganesan (Hong Kong Baptist University)H-Index: 7
Last. Baojun Xu (Hong Kong Baptist University)H-Index: 30
view all 3 authors...
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#1Kumar Ganesan (United International College)H-Index: 7
#2Sookja K. Chung (United International College)H-Index: 36
Last. Baojun Xu (United International College)H-Index: 30
view all 4 authors...
The incidence of metabolic disorders, including diabetes, has elevated exponentially during the last decades and enhanced the risk of a variety of complications, such as diabetes and cardiovascular diseases. In the present review, we have highlighted the new insights on the complex relationships between diet-induced modulation of gut microbiota and metabolic disorders, including diabetes. Literature from various library databases and electronic searches (ScienceDirect, PubMed, and Google Scholar...
5 CitationsSource
#1Tongze Zhang (Hong Kong Baptist University)H-Index: 1
#2Muthukumaran Jayachandran (Hong Kong Baptist University)H-Index: 7
Last. Baojun Xu (Hong Kong Baptist University)H-Index: 30
view all 4 authors...
Background and purpose: Tuber melanosporum (black truffle) has been considered as a medicinal mushroom for a long time. T. melanosporum has the ability to attenuate oxidative stress and in turn diabetes mellitus (DM). DM has become an awfully common chronic unwellness, threatening people’s well-being. There are nearly 1 in 10 people in the world affected by diabetes. Oxidative stress plays a crucial role in vascular complications related to DM. Our study aimed to attain an effective treatment me...
2 CitationsSource
Obesity is a group of metabolic disorders caused by multiple factors, including heredity, diet, lifestyle, societal determinants, environment, and infectious agents, which can all lead to the enhancement of storage body fat. Excess visceral fat mass in adipose tissue generate several metabolic disorders, including cardiovascular diseases with chronic inflammation based pathophysiology. The objective of the current review is to summarize the cellular mechanisms of obesity that attenuate by antiox...
3 CitationsSource
#2Kumar GanesanH-Index: 7
Last. Baojun XuH-Index: 30
view all 3 authors...
The present study aims to examine the protective effect of Justicia tranquebariesis on thioacetamide (TAA)-induced oxidative stress and hepatic fibrosis. Male Wister albino rats (150–200 g) were divided into five groups. Group 1 was normal control. Group 2 was J. tranquebariensis (400 mg/kg bw/p.o.)-treated control. Group 3 was TAA (100 mg/kg bw/s.c.)-treated control. Groups 4 and 5 were orally administered with the leaf extract of J. tranquebariensis (400 mg/kg bw) and silymarin (50 mg/kg bw) d...
3 CitationsSource
#1Kumar Ganesan (Hong Kong Baptist University)H-Index: 7
#2Muthukumaran Jayachandran (Hong Kong Baptist University)H-Index: 7
Last. Baojun Xu (Hong Kong Baptist University)H-Index: 30
view all 3 authors...
ABSTRACTBackground: Bioactive food components are nonessential biomolecules, which help to give beneficial effects to human being against several diseases. Natural bioactive food components derived from plants and animals, such as phytosterols, carotenoids, polyphenols and fatty acids, have been proposed as valuable substitutions for anticipation and management of hepatotoxic effects and its chronic complications based on in vitro and in vivo studies.Objectives of the study: To summarize drugs a...
10 CitationsSource
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