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Xavier Heiligenstein
PSL Research University
13Publications
4H-index
331Citations
Publications 13
Newest
Published on Mar 15, 2019in Journal of Cell Science 4.40
Christin Bissig2
Estimated H-index: 2
,
Pauline Croisé1
Estimated H-index: 1
+ 9 AuthorsLois S. Weisman42
Estimated H-index: 42
There was an error in J. Cell Sci. (2019) 132, [jcs229500][1] ([doi:10.1242/jcs.229500][2]). The DMSO lanes in [Fig. 2][3]C and D were duplicated in [Fig. 2][3]E and F, respectively, which contravenes our image presentation guidelines. The authors supplied full blots for all these panels and
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Published on Mar 1, 2019in Journal of Cell Science 4.40
Christin Bissig2
Estimated H-index: 2
(CNRS: Centre national de la recherche scientifique),
Pauline Croisé1
Estimated H-index: 1
(Paris V: Paris Descartes University)
+ 9 AuthorsLois S. Weisman42
Estimated H-index: 42
(UM: University of Michigan)
The metabolism of PI(3,5)P2 is regulated by the PIKfyve, VAC14 and FIG4 complex, whose mutations are associated with hypopigmentation in mice. These pigmentation defects indicate a key but yet unexplored physiological relevance of this complex in the biogenesis of melanosomes. Here we show that PIKfyve activity regulates formation of amyloid matrix composed of PMEL protein within early endosomes, called stage I melanosomes. PIKfyve activity controls the membrane remodeling of stage I melanosomes...
1 Citations Source Cite
Published on Aug 6, 2018in Journal of Cell Biology 8.78
Léa Ripoll1
Estimated H-index: 1
(CNRS: Centre national de la recherche scientifique),
Xavier Heiligenstein1
Estimated H-index: 1
(CNRS: Centre national de la recherche scientifique)
+ 8 AuthorsGraça Raposo92
Estimated H-index: 92
(CNRS: Centre national de la recherche scientifique)
Vesicular and tubular transport intermediates regulate organellar cargo dynamics. Transport carrier release involves local and profound membrane remodeling before fission. Pinching the neck of a budding tubule or vesicle requires mechanical forces, likely exerted by the action of molecular motors on the cytoskeleton. Here, we show that myosin VI, together with branched actin filaments, constricts the membrane of tubular carriers that are then released from melanosomes, the pigment containing lys...
4 Citations Source Cite
Published on Apr 1, 2018
Bertha Mayela Toledo Acosta1
Estimated H-index: 1
(IRIA: French Institute for Research in Computer Science and Automation),
Xavier Heiligenstein4
Estimated H-index: 4
(PSL Research University)
+ 1 AuthorsPatrick Bouthemy37
Estimated H-index: 37
(IRIA: French Institute for Research in Computer Science and Automation)
Correlative microscopy, especially light and electron microscopy (CLEM), enables the study of cells and subcellular elements in complementary ways, provided a reliable registration between images is efficiently achievable. We propose a general automatic registration method. Due to large discrepancies in appearance, field-of-view, resolution and position, a pre-alignment stage is required before any 3D fine registration stage. We define an intensity-based method for both stages, which leverages a...
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Published on Jul 1, 2017in Microscopy and Microanalysis 2.12
Xavier Heiligenstein4
Estimated H-index: 4
,
Perrine Paul-Gilloteaux13
Estimated H-index: 13
+ 2 AuthorsJean Salamero34
Estimated H-index: 34
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Published on Mar 1, 2017in Nature Methods 26.92
Perrine Paul-Gilloteaux13
Estimated H-index: 13
,
Xavier Heiligenstein4
Estimated H-index: 4
+ 5 AuthorsJean Salamero34
Estimated H-index: 34
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Published on Feb 1, 2017in Nature Methods 26.92
Perrine Paul-Gilloteaux13
Estimated H-index: 13
(PSL Research University),
Xavier Heiligenstein4
Estimated H-index: 4
(PSL Research University)
+ 5 AuthorsJean Salamero34
Estimated H-index: 34
(PSL Research University)
33 Citations Source Cite
Published on Jan 1, 2017in Methods in Cell Biology 1.59
Xavier Heiligenstein4
Estimated H-index: 4
(PSL Research University),
Perrine Paul-Gilloteaux2
Estimated H-index: 2
(University of Nantes)
+ 1 AuthorsJean Salamero34
Estimated H-index: 34
(PSL Research University)
Abstract Correlative light and electron microscopy (CLEM) is a scientific method covered by a broad range of techniques. The path taken to explore a scientific question is often driven both by the question and the technology available. Yet, one common step to all CLEM workflows is the registration of the multimodal images to assign a fluorescent signal to an ultrastructure. The manual relocation and registration of light microscopy and electron microscopy images can be challenging and time-consu...
2 Citations Source Cite
12