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David German
Oregon Health & Science University
11Publications
1H-index
2Citations
Publications 11
Newest
Erick A. Perez-Alday2
Estimated H-index: 2
(OHSU: Oregon Health & Science University),
Kazi Haq (OHSU: Oregon Health & Science University)+ -3 AuthorsJason Thomas3
Estimated H-index: 3
(OHSU: Oregon Health & Science University)
Background: Mechanisms of arrhythmogenicity in hypertrophic cardiomyopathy (HCM) are not well understood. We hypothesized that HCM is characterized by the specific electrophysiological substrate as compared to patients with ischemic cardiomyopathy (ICM), or healthy individuals. Methods: We conducted a prospective case-control study. HCM patients at high risk for ventricular tachyarrhythmia (VT) (n=10; age 61 ± 9 y; left ventricular ejection fraction (LVEF) 60 ± 9%) and three control groups (Heal...
Published on Jun 21, 2019in bioRxiv
Stacey J. Howell (OHSU: Oregon Health & Science University), David German1
Estimated H-index: 1
(OHSU: Oregon Health & Science University)
+ 9 AuthorsAshley Wirth (OHSU: Oregon Health & Science University)
Background: Sex is a well-recognized risk factor for sudden cardiac death (SCD). Sex differences in electrophysiological (EP) substrate of SCD are known. However, it remains unknown whether sex can modify an association of EP substrate with SCD. Methods: Participants from the Atherosclerosis Risk in Communities study with analyzable ECGs (n=14,725; age, 54.2 +/- 5.8 yrs; 55% female, 74% white) were included. EP substrate was characterized by traditional 12-lead ECG (heart rate, QRS, QTc, Cornell...
Published on May 1, 2019in Annals of Noninvasive Electrocardiology 1.24
Jason Thomas3
Estimated H-index: 3
(OHSU: Oregon Health & Science University),
Erick A. Perez-Alday2
Estimated H-index: 2
(OHSU: Oregon Health & Science University)
+ 6 AuthorsLarisa G. Tereshchenko19
Estimated H-index: 19
(OHSU: Oregon Health & Science University)
Published on Feb 1, 2019in JACC: Basic to Translational Science
David German1
Estimated H-index: 1
(Cardiovascular Institute of the South),
Shoukhrat Mitalipov36
Estimated H-index: 36
(Cardiovascular Institute of the South)
+ 1 AuthorsSanjiv Kaul81
Estimated H-index: 81
(Cardiovascular Institute of the South)
Summary A variety of genetic cardiovascular diseases may one day be curable using gene editing technology. Germline genome editing and correction promises to permanently remove monogenic cardiovascular disorders from the offspring and subsequent generations of affected families. Although technically feasible and likely to be ready for implementation in humans in the near future, this approach remains ethically controversial. Although currently beset by several technical challenges, and not yet p...
Published on Jan 8, 2019in bioRxiv
Erick A. Perez-Alday2
Estimated H-index: 2
(OHSU: Oregon Health & Science University),
Aron Bender1
Estimated H-index: 1
(OHSU: Oregon Health & Science University)
+ 6 AuthorsLarisa G. Tereshchenko19
Estimated H-index: 19
(OHSU: Oregon Health & Science University)
Background: The risk of sudden cardiac death (SCD) is known to be dynamic. However, an accuracy of a dynamic SCD prediction, and expiration date of ECG biomarkers is unknown. Our goal was to measure dynamic predictive accuracy of ECG biomarkers of SCD and competing outcomes. Methods: Atherosclerosis Risk In Community study participants with analyzable digital ECGs were included (n=15,768; 55% female, 73% white, age 54.2±5.8 y). ECGs of 5 follow-up visits were analyzed. Global electrical heteroge...
Published on Jan 1, 2019in European Journal of Haematology 2.22
Elise A. Larson (OHSU: Oregon Health & Science University), David German1
Estimated H-index: 1
(OHSU: Oregon Health & Science University)
+ 1 AuthorsThomas G. DeLoughery21
Estimated H-index: 21
(OHSU: Oregon Health & Science University)
Published on Mar 20, 2018in Circulation 23.05
Abhishek Maan7
Estimated H-index: 7
,
David German1
Estimated H-index: 1
+ 11 AuthorsScott D. Solomon104
Estimated H-index: 104
Introduction: The association between premature ventricular contractions (PVCs) and Sudden Cardiac Death (SCD) remains controversial. Hypothesis: We hypothesized that PVCs are associated with SCD. Methods: Presence of PVCs was detected on 12-lead ECG recorded at baseline or any of 4 follow-up visits in 15,667 participants (pts) (mean age: 54.2 + 5.8 Yrs; 55% female; 73% Whites) of the Atherosclerosis Risk in Communities (ARIC) study. For validation cohort, we included baseline and 9 follow-up vi...
Published on Mar 20, 2018in Circulation 23.05
Aron Bender1
Estimated H-index: 1
,
Muammar M. Kabir10
Estimated H-index: 10
+ 9 AuthorsElsayed Z. Soliman47
Estimated H-index: 47
Introduction: Poincare plot asymmetry has been associated with sustained ventricular tachyarrhythmias, implicating involvement of the autonomic nervous system. An association between sudden cardiac...
Published on Mar 1, 2018in Journal of the American College of Cardiology 18.64
David German1
Estimated H-index: 1
(OHSU: Oregon Health & Science University),
Erick A. Perez-Alday2
Estimated H-index: 2
(OHSU: Oregon Health & Science University)
+ 9 AuthorsNona Sotoodehnia (OHSU: Oregon Health & Science University)
The Selvester score (SS) was created to estimate myocardial infarct size from the QRS complex on the ECG. We hypothesized that SS is associated with sudden cardiac death (SCD). ECGs from baseline and subsequent visits of the Atherosclerosis Risk in Communities (ARIC) study (N = 15,722; mean age 54.
Published on Nov 14, 2017in Circulation 23.05
Aron Bender1
Estimated H-index: 1
,
Muammar M. Kabir10
Estimated H-index: 10
+ 9 AuthorsElsayed Z. Soliman47
Estimated H-index: 47
Introduction: Poincare plot asymmetry has been associated with sustained ventricular tachyarrhythmias, implicating involvement of the autonomic nervous system. Porta’s index provides a quantitative assessment of the degree and direction of temporal asymmetry in heart rate variability (HRV), either toward relative bradycardia or tachycardia. The association between temporal asymmetry of HRV with sudden cardiac death (SCD) in the general population has not been previously studied. Hypothesis: We h...
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