Han Xu
Amgen
2Publications
1H-index
3Citations
Publications 2
Newest
Published on Feb 13, 2019in bioRxiv
Antony Chi Shing Chan (California Institute of Technology), Jinho Kim (California Institute of Technology)+ 5 AuthorsChanghuei Yang (California Institute of Technology)
We report the implementation of a parallel microscopy system (96 Eyes) that is capable of simultaneous imaging of all wells on a 96 well plate. The optical system consists of 96 microscopy units, where each unit is made out of a four element objective, made through a molded injection process, and a low cost CMOS camera chip. By illuminating the sample with angle varying light and applying Fourier Ptychography, we can improve the effective brightfield imaging NA of the objectives from 0.23 to 0.3...
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Published on Nov 1, 2017in Pharmacological Research 4.90
Patrick J. Collins2
Estimated H-index: 2
(Amgen),
Christopher M. Hale13
Estimated H-index: 13
(Amgen),
Han Xu1
Estimated H-index: 1
(Amgen)
Abstract Within the short few years since the report of its application in precise genome editing, CRISPR technology has become the method of choice to modify and modulate gene expression in biomedical research and therapeutic development. Subsequently, a variety of research, diagnostic, and therapeutic tools have been developed based upon CRISPR’s mechanism of action. Such tools have helped to deepen the understanding of fundamental biology and broaden the horizon in the search for treatments f...
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