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Wai Ming Li
University of Northern British Columbia
PolysaccharideMushroomAnti-inflammatoryBiochemistryMicrobiology
4Publications
2H-index
7Citations
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Publications 5
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#1Almas Yaqoob (UNBC: University of Northern British Columbia)H-Index: 1
#2Wai Ming Li (UNBC: University of Northern British Columbia)H-Index: 2
Last. Chow H. Lee (UNBC: University of Northern British Columbia)H-Index: 9
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In our search for bioactive mushrooms native to British Columbia, we determined that the ethanol extracts from fruiting bodies of the terrestrial polypore Albatrellus flettii had potent anti-cell viability activity. Using bioassay-guided fractionation, mass spectrometry and nuclear magnetic resonance, we successfully isolated three known compounds (grifolin, neogrifolin and confluentin). These compounds represent the major anti-cell viability components from the ethanol extracts of A. flettii. W...
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#1Sumreen JavedH-Index: 1
#2Wai Ming LiH-Index: 2
Last. Chow H. LeeH-Index: 9
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The aim of this study was to investigate the anti-inflammatory activity of a previously un-studied wild mushroom, Echinodontium tinctorium, collected from the forests of north-central British Columbia. The lipopolysaccharide (LPS)-induced RAW264.7 macrophage model was used to study the in vitro anti-inflammatory activity. The crude alkaline extract demonstrated potent anti-inflammatory activity, and was further purified using a “bio-activity-guided-purification” approach. The size-exclusion and ...
1 CitationsSource
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#1Ankush Barad (UNBC: University of Northern British Columbia)H-Index: 2
#2Sebastian Mackedenski (UNBC: University of Northern British Columbia)H-Index: 4
Last. Chow H. Lee (UNBC: University of Northern British Columbia)H-Index: 9
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• Polysaccharide (GIPinv) with anti-cancer activity was purified from Paxillus involutus .
4 CitationsSource
#1Aaron Smith (UNBC: University of Northern British Columbia)H-Index: 1
#2Sumreen Javed (UNBC: University of Northern British Columbia)H-Index: 1
Last. Chow H. Lee (UNBC: University of Northern British Columbia)H-Index: 1
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Wild mushrooms, especially from North America, have not been systematically explored for their medicinal properties. Here we report screening for the growth-inhibitory and immunomodulatory activities of 12 species collected from multiple locations in north-central British Columbia, Canada. Mushrooms were characterized using morphology and DNA sequencing, followed by chemical extraction into 4 fractions using 80% ethanol, 50% methanol, water, and 5% sodium hydroxide. Growth-inhibitory, immunostim...
3 CitationsSource
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