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Gailian Zhang
Shanxi Medical University
Physical therapyMesenchymal stem cellUmbilical cordDiabetes mellitusMedicine
7Publications
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Publications 8
Newest
#1Jinfang Gao (Shanxi Medical University)
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BACKGROUND: Rheumatoid arthritis (RA) is characterized by joint inflammation and damage to the cartilage and bone in collagen-induced arthritis (CIA). Mesenchymal stem cells (MSCs) can improve articular symptoms and reduce bone erosion in CIA rats; however, the underlying mechanism remains unknown. This study aimed to investigate the mechanism underlying MSC-induced improvement of bone destruction in CIA. METHODS: Wistar rats were divided into a normal group, CIA control group, MTX intervention ...
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#1Dan Ma (Shanxi Medical University)H-Index: 1
#2Ke Xu (Shanxi Medical University)
Last. Liyun Zhang (Shanxi Medical University)
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Abstract Rheumatoid arthritis (RA) is an autoimmune disease which is lack of effective therapies. Abnormal activation, proliferation, and differentiation of T lymphocytes are closely related to RA. Mesenchymal stem cells (MSCs) can be used for RA treatment due to their immunoregulatory effects. However, the specific molecular mechanisms have not been fully elucidated and the therapeutic effect has been inconsistent. This study investigated the immunomodulatory effect of human umbilical cord MSCs...
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#1Na Zhang (Shanxi Medical University)
#2Liyun Zhang (Shanxi Medical University)
Last. Ke Xu (Shanxi Medical University)
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Background: Recently, studies have shown that Mesenchymal Stem Cell-derived Microvesicles(MSC-MVs) can play a role in immune regulation and tissue repair by transporting miRNAs, and their effects are not weaker than that of their mother stem cells. Rheumatoid arthritis is an autoimmune disease characterized by chronic synovitis and progressive cartilage and bone destruction. Current treatments include non-steroidal anti-inflammatory drugs, glucocorticoids, DMARDs, and biological agents, but 30% ...
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Background Behcet9s disease is a systemic vasculitis disease of unknown etiology. Oral ulcer is the most common symptoms, the ulcer is various, the swelling and pain is obvious, and it is easy to recurrent, these symptoms affected the patient9s diet and life seriously.Therefore, it is important to care the patients with Behcet9s disease of oral ulcer.The ozonated water had many functions such as immune activation and immune regulation, it can induce the production of many cytokines,promote the r...
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Background Gout is a heterogeneous disease characterized by increased levels of blood uric acid. It is difficult to achieve a comprehensive and effective control of gout only by drugs, drug therapy must be combined with health education, diet and lifestyle changes. However, most of the gout patients had wrong thinking about their disease, diet and drug therapy.The status of China9s health education in gout patients:the research teams were dispersed and unstable, the content of health education n...
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