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Takahiro Tsuji
University of Toyama
Coalescence (physics)CreamingChemistryEmulsionChromatography
2Publications
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#1Takahiro Tsuji (University of Toyama)H-Index: 1
#2Koji Mochizuki (Hoshi University)
Last. Yoshinori Onuki (University of Toyama)H-Index: 15
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Abstract The time–temperature superposition principle (TTSP) was applied to the destabilization kinetics of a pharmaceutical emulsion. The final goal of this study is to predict precisely the emulsion stability after long-term storage from the short-period accelerated test using TTSP. As the model emulsion, a cream preparation that is clinically used for the treatment of pruritus associated with chronic kidney disease was tested. After storage at high temperatures ranging from 30 to 45 °C for de...
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#1Yoshihiro Hayashi (University of Toyama)H-Index: 7
#2Takahiro Tsuji (University of Toyama)H-Index: 1
Last. Yoshinori Onuki (University of Toyama)H-Index: 15
view all 9 authors...
Abstract In this study, we evaluated the correlation between the response surfaces for the tablet characteristics of placebo and active pharmaceutical ingredient (API)-containing tablets. The quantities of lactose, cornstarch, and microcrystalline cellulose were chosen as the formulation factors. Ten tablet formulations were prepared. The tensile strength (TS) and disintegration time (DT) of tablets were measured as tablet characteristics. The response surfaces for TS and DT were estimated using...
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