Vipul Jairath
University of Western Ontario
Publications 161
#1Brennan C Kahan (QMUL: Queen Mary University of London)H-Index: 25
#2Michael Tsui (UWO: University of Western Ontario)
Last.Diana Elbourne (Lond: University of London)H-Index: 62
view all 7 authors...
Abstract Objective Factorial designs can allow efficient evaluation of multiple treatments within a single trial. We evaluated the design, analysis, and reporting in a sample of factorial trials. Study design and setting Review of 2x2 factorial trials evaluating health-related interventions and outcomes in humans. Using MEDLINE, we identified articles published between January 2015 and March 2018. We randomly selected 100 articles for inclusion. Results Few trials (22%) provided a rationale for ...
#1Amy Brenner (Lond: University of London)H-Index: 2
#2Adefemi O. Afolabi (University College Hospital, Ibadan)H-Index: 2
Last.Ian Roberts Mbbch (Lond: University of London)H-Index: 82
view all 18 authors...
Acute gastrointestinal (GI) bleeding is an important cause of mortality worldwide. Bleeding can occur from the upper or lower GI tract, with upper GI bleeding accounting for most cases. The main causes include peptic ulcer/erosive mucosal disease, oesophageal varices and malignancy. The case fatality rate is around 10% for upper GI bleeding and 3% for lower GI bleeding. Rebleeding affects 5–40% of patients and is associated with a four-fold increased risk of death. Tranexamic acid (TXA) decrease...
#1Adam Rahman (Lawson Health Research Institute)H-Index: 1
#2Vipul Jairath (UWO: University of Western Ontario)H-Index: 14
Last.Eric I. Benchimol (U of O: University of Ottawa)H-Index: 31
view all 11 authors...
#1Pieter Hindryckx (UGent: Ghent University)H-Index: 18
#2Vipul Jairath (UWO: University of Western Ontario)H-Index: 14
Last.Jordi RimolaH-Index: 29
view all 17 authors...
Abstract Background & Aims There is no validated magnetic resonance imaging (MRI) index for assessment of perianal fistulas in patients with Crohn’s disease (CD). We developed and internally validated a new instrument. Methods We used paired baseline and week 24 MRI scans from 160 participants in a randomized placebo-controlled trial of stem cell therapy for patients with perianal fistulizing CD. Four radiologists scored disease activity using index items identified during previous studies and e...
#1Dominik BettenworthH-Index: 15
#2Marcus M. MückeH-Index: 3
Last.Florian Rieder (Cleveland Clinic)H-Index: 30
view all 23 authors...
Background & Aims Little is known about the effects of endoscopic balloon dilation (EBD) for strictures of the upper gastrointestinal (UGI) tract in patients with Crohn’s disease (CD). We performed a pooled analysis of the efficacy and safety of EBD for UGI CD-associated strictures. Methods We searched Embase, Medline, and the Cochrane library, as well as bibliographies of relevant articles, for cohort studies of adults with CD and strictures of the stomach or duodenum (up to the ligament of Tre...
#1Saleh Al Draiweesh (UWO: University of Western Ontario)
#2Christopher Ma (U of C: University of Calgary)H-Index: 13
Last.Vipul Jairath (UWO: University of Western Ontario)H-Index: 14
view all 23 authors...
#1Berkeley N. Limketkai (Stanford University)H-Index: 12
#2Siddharth Singh (UCSD: University of California, San Diego)H-Index: 39
Last.Parambir S. Dulai (UCSD: University of California, San Diego)H-Index: 20
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#1Robert Battat (UCSD: University of California, San Diego)H-Index: 11
#2Parambir S. Dulai (UCSD: University of California, San Diego)H-Index: 20
Last.Niels Vande Casteele (UCSD: University of California, San Diego)H-Index: 24
view all 4 authors...
ABSTRACTVedolizumab is a monoclonal antibody to the α4β7 integrin that selectively reduces intestinal lymphocyte trafficking, thereby providing a safe and effective treatment option for patients wi...
#1Vipul Jairath (UWO: University of Western Ontario)H-Index: 14
#2Brian G. Feagan (UWO: University of Western Ontario)H-Index: 95