Nerges Winblad
Karolinska Institutet
Publications 3
#1Nicolás M Ortega (KI: Karolinska Institutet)
#2Nerges Winblad (KI: Karolinska Institutet)H-Index: 1
Last.Fredrik Lanner (KI: Karolinska Institutet)H-Index: 20
view all 4 authors...
Understanding the genetic underpinning of early human development is of great interest not only for basic developmental and stem cell biology but also for regenerative medicine, infertility treatments, and better understanding the causes of congenital disease. Our current knowledge has mainly been generated with the use of laboratory animals, especially the mouse. While human and mouse early development present morphological resemblance, we know that the timing of the events as well as the cellu...
The gene-editing technology CRISPR–Cas has been used in human embryos grown in vitro to correct a disease-associated mutation. The introduction of editing components at fertilization aided repair efficiency. See Article p.413
#1Nerges WinbladH-Index: 1
#2Fredrik LannerH-Index: 20
La tecnica CRISPR-Cas se ha ensayado en el laboratorio para corregir una mutacion causante de una enfermedad. Su aplicacion durante la fecundacion in vitro mejora la eficacia de la edicion.