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Mari-Liis Tammesoo
University of Tartu
24Publications
13H-index
7,772Citations
Publications 26
Newest
#1Sonia Shah (UCL: University College London)H-Index: 36
#2Albert Henry (UCL: University College London)H-Index: 1
Last.R Thomas LumbersH-Index: 3
view all 146 authors...
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained. We report results from a GWAS meta-analysis of HF comprising 47,309 cases and 930,014 controls. Twelve independent variants at 11 genomic loci are associated with HF, all of which demonstrate one o...
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#1Sonia Shah (UCL: University College London)H-Index: 36
#2Albert Henry (UCL: University College London)
Last.R Thomas Lumbers (UCL: University College London)H-Index: 3
view all 147 authors...
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained. We report the largest GWAS meta-analysis of HF to-date, comprising 47,309 cases and 930,014 controls. We identify 12 independent associations with HF at 11 genomic loci, all of which demonstrate on...
Source
#1Honor Bixby (Imperial College London)H-Index: 10
#2James BenthamH-Index: 13
Last.Majid Ezzati (Imperial College London)H-Index: 107
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Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbaniz ...
13 CitationsSource
#1Majid Ezzati (Imperial College London)H-Index: 107
#2Bin Zhou (Imperial College London)H-Index: 17
Last.Julio Zuniga CisnerosH-Index: 8
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Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood press...
10 CitationsSource
#1Majid EzzatiH-Index: 107
#2James BenthamH-Index: 13
Last.Julio Zuniga CisnerosH-Index: 8
view all 1024 authors...
#1Bin ZhouH-Index: 17
#2James BenthamH-Index: 13
Last.Julio Zuniga CisnerosH-Index: 8
view all 841 authors...
22 Citations
#2Ziad AbdeenH-Index: 26
Last.Majid Ezzati (Imperial College London)H-Index: 107
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BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in ...
568 CitationsSource
#1Bin ZhouH-Index: 17
#2James BenthamH-Index: 13
Last.Julio Zuniga CisnerosH-Index: 8
view all 752 authors...
1 Citations
#1Bin Zhou (Imperial College London)H-Index: 17
#2James Bentham (Imperial College London)H-Index: 13
Last.Julio Zuniga CisnerosH-Index: 8
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Summary Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this analysis, we pooled national, subnational, or community population-based studies that had meas...
374 CitationsSource
#1Giuseppe RobertoH-Index: 7
#2I Leal (Erasmus University Medical Center)H-Index: 3
Last.Rosa GiniH-Index: 20
view all 24 authors...
Due to the heterogeneity of existing European sources of observational healthcare data, data source-tailored choices are needed to execute multi-data source, multi-national epidemiological studies. This makes transparent documentation paramount. In this proof-of-concept study, a novel standard data derivation procedure was tested in a set of heterogeneous data sources. Identification of subjects with type 2 diabetes (T2DM) was the test case. We included three primary care data sources (PCDs), th...
5 CitationsSource
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