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Keiichirou Okada
Kanazawa Medical University
AntigenMannan-binding lectinMembranous nephropathyImmunoglobulin GKidney Glomerulus
2Publications
1H-index
14Citations
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Publications 2
Newest
#1Norifumi Hayashi (Kanazawa Medical University)H-Index: 4
#2Keiichirou Okada (Kanazawa Medical University)H-Index: 1
Last. Hitoshi Yokoyama (Kanazawa Medical University)H-Index: 37
view all 11 authors...
Background Thrombotic microangiopathy (TMA) in patients with connective tissue disease is rare but life-threatening. In particular, the survival rate of patients with dermatomyositis (DM) that develop TMA is low. The effectiveness of plasma exchange (PEX) therapy is unclear for the treatment of TMA secondary to DM.
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#1Norifumi Hayashi (Kanazawa Medical University)H-Index: 4
#2Keiichirou Okada (Kanazawa Medical University)H-Index: 1
Last. Hitoshi Yokoyama (Kanazawa Medical University)H-Index: 37
view all 8 authors...
Background: The M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A) were identified as intrinsic antigens in primary membranous nephropathy (MN). Complement activation via the lectin pathway in intrinsic antigen-related MN is still unclear. Methods: We retrospectively enrolled 60 primary Japanese MN patients and detected activated complement pathways by staining complement proteins in glomerular deposition. According to the findings of PLA2R and THSD7...
8 CitationsSource
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