Elena Pérez
European University of Madrid
ChemistryBiocatalysisNucleosideImmobilized enzymeBiochemistry
What is this?
Publications 3
#1Jon Del Arco (UEM: European University of Madrid)H-Index: 6
#2Elena Pérez (UEM: European University of Madrid)H-Index: 2
Last. Jesús Fernández-Lucas (Grupo México)H-Index: 15
view all 6 authors...
Abstract The present work describes the functional and structural characterization of adenine phosphoribosyltransferase 2 from Thermus thermophilus HB8 (TtAPRT2). The combination of structural and substrate specificity data provided valuable information for immobilization studies. Dimeric TtAPRT2 was immobilized onto glutaraldehyde-activated MagReSyn®Amine magnetic iron oxide porous microparticles by two different strategies: a) an enzyme immobilization at pH 8.5 to encourage the immobilization ...
5 CitationsSource
#1Elena Pérez (UEM: European University of Madrid)H-Index: 2
#2Pedro A. Sánchez-Murcia (University of Vienna)H-Index: 10
Last. Jesús Fernández-Lucas (Grupo México)H-Index: 15
view all 7 authors...
10 CitationsSource
#1Ana M. MartínezH-Index: 12
#2Marta Benito (RAFAEL: Rafael Advanced Defense Systems)H-Index: 6
Last. María Dolores BlancoH-Index: 17
view all 4 authors...
Cancer has become one of the main causes of death in developed countries. Nanomedicine aims to overcome some problems related to this prevalent disease, particularly the lack of efficient diagnostic and therapeutic tools. Nanocarriers can target cancer by simply being entrapped in tumors or by specific recognition of grafted ligands by cell surface receptors, thus leading to receptor-mediated endocytosis. Among several tumor-selective ligands, folic acid displays high affinity for folate recepto...