J. D. McGarry
University of Texas Southwestern Medical Center
Publications 2
#1J. D. McGarry (UTSW: University of Texas Southwestern Medical Center)H-Index: 2
#2R. L. Dobbins (UTSW: University of Texas Southwestern Medical Center)H-Index: 1
tant energy source for most body tissues, particularly during periods of food deprivation, but recent evidence suggests that these same molecules subserve a much broader function in whole body fuel homeostasis by virtue of their ability to act as potent signalling entities in a variety of cellular processes. One such auxiliary role of NEFA is to heighten the responsiveness of the pancreatic beta cell to a variety of insulin secretagogues. Importantly, this fatty acid-beta cell interaction, thoug...
#1A. Björklund (KI: Karolinska Institutet)H-Index: 3
#2G. Yaney (BMC: Boston Medical Center)H-Index: 1
Last.Gordon C. Weir (Joslin Diabetes Center)H-Index: 83
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at the Third JDF World Conference on Diabetes Research held in Monaco in 1991 there was little, if any, mention of the role of fatty acids in pancreatic betacell function. However, this situation has now changed dramatically on the heels of two recent and simultaneousdevelopments. The first has to do with the notion that there is at work within the beta cell, just as in other tissues, an important element of glucose-fatty acid “cross-talk” which appears to be essential for the normal regulation ...