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Maximiliano Gelli
Institut Gustave Roussy
SurgeryHyperthermic intraperitoneal chemotherapyColorectal cancerGeneral surgeryMedicine
29Publications
7H-index
127Citations
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Publications 27
Newest
#1Léonor BenhaimH-Index: 10
#2Matthieu FaronH-Index: 8
Last. Michel DucreuxH-Index: 83
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Source
#1Olivier Glehen (University of Lyon)H-Index: 47
#2Vahan Kepenekian (University of Lyon)H-Index: 9
Last. J.-B. DelhormeH-Index: 8
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The Covid-19 pandemic is profoundly changing the organization of healthcare access. This is particularly so for peritoneal neoplastic diseases, for which curative treatment mobilizes substantial personnel, operating room and intensive care resources. The BIG-RENAPE and RENAPE groups have made tentative proposals for prioritizing care provision.A tightening of the usual selection criteria is needed for curative care: young patients with few or no comorbidities and limited peritoneal extension. It...
1 CitationsSource
#1Olivier Glehen (University of Lyon)H-Index: 47
#2Vahan Kepenekian (University of Lyon)H-Index: 9
Last. J.-B. DelhormeH-Index: 8
view all 30 authors...
Resume La pandemie de COVID-19 modifie profondement l’organisation et l’acces aux soins, en particulier pour les pathologies neoplasiques peritoneales, dont la prise en charge curative mobilise des moyens importants en personnel, bloc operatoire et reanimation. Les groupes BIG-RENAPE et RENAPE proposent des pistes de reflexion et de priorisation pour leur prise en charge. Un renforcement des criteres habituels de selection est necessaire pour une prise en charge a visee curative : patients jeune...
Source
#1Frederic DeschampsH-Index: 28
#2Maxime Ronot (Beaujon Hospital)H-Index: 25
Last. Lambros Tselikas (Université Paris-Saclay)H-Index: 15
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To discuss the pivotal role of Interventional radiology (IR) for the management of colorectal liver metastases (CRLM). IR has three main objectives for the treatment of CRLM: Radiofrequency ablation (RFA) is the most reported percutaneous ablation technique and provides high local control rates that exceed 90% for small metastases (< 3 cm). Novel technologies such as microwave ablation could help overcome some limitations of RFA. Liver metastases non-amenable to radical treatment can, because of...
Source
#1Alice BoilèveH-Index: 5
Last. Veronique Guerin-MeyerH-Index: 8
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BACKGROUND: Approximately 40% of colorectal cancer patients will develop colorectal liver metastases (CRLM). The most effective approach to increase long-term survival is CRLM complete resection. Unfortunately, only 10-15% of CRLM are initially considered resectable. The objective response rates (ORR) after current first-line systemic chemotherapy (sys-CT) regimens range from 40 to 80% and complete resection rates (CRR) range from 25 to 50% in patients with initially unresectable CRLM. When CRLM...
Source
#1Fotine Libanje (French Institute of Health and Medical Research)H-Index: 3
#2Joel Raingeaud (French Institute of Health and Medical Research)H-Index: 4
Last. Fanny Jaulin (French Institute of Health and Medical Research)H-Index: 3
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: The metastatic progression of cancer is a multi-step process initiated by the local invasion of the peritumoral stroma. To identify the mechanisms underlying colorectal carcinoma (CRC) invasion, we collected live human primary cancer specimens at the time of surgery and monitored them ex vivo. This revealed that conventional adenocarcinomas undergo collective invasion while retaining their epithelial glandular architecture with an inward apical pole delineating a luminal cavity. To identify th...
1 CitationsSource
#1Michel Ducreux (Université Paris-Saclay)H-Index: 83
#2Ali N. ChamseddineH-Index: 4
Last. Maximiliano GelliH-Index: 7
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Over the past two decades, the molecular characterization of metastatic colorectal cancer (mCRC) has been revolutionized by the routine implementation of RAS and BRAF tests. As a result, it is now ...
1 CitationsSource
#1Leonor BenhaimH-Index: 2
#2Matthieu FaronH-Index: 8
Last. Diane GoéréH-Index: 39
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Abstract Introduction The optimal treatment for pseudomyxoma peritonei (PMP) combines complete cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). Yet, achieving CRS is challenging in the case of extensive involvement of the peritoneal cavity and the survival benefit in this setting remains uncertain. The present study evaluated the surgical outcomes according to the peritoneal extent. Methods Between 1992 and 2014, 245 patients underwent CRS and HIPEC for PMP in ...
1 CitationsSource
#1Valérie BoigeH-Index: 59
#2J.P. PignonH-Index: 62
Last. Julien Taieb (Paris V: Paris Descartes University)H-Index: 37
view all 12 authors...
TPS3619Background: In the first-line setting, current combination chemotherapy (CT) achieve high objective response rates (ORR) ranging from 40% to 80% and leads to complete resection rate (CRR) of...
Source
#1A. MarianiH-Index: 3
#2Maximiliano GelliH-Index: 7
Last. Diane GoéréH-Index: 39
view all 8 authors...
Background Management of limited synchronous colorectal peritoneal metastases (CRPM) is critical to outcome. Resection of the primary tumor and CRPM can be performed concurrently, followed by hyperthermic intraperitoneal chemotherapy (HIPEC) either immediately, during the same procedure (one-stage), or during a systematic second-stage procedure (two-stage).
1 CitationsSource
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