Claire Mokrysz
University College London
PsychiatryPsychologyCannabisEffects of cannabisClinical psychology
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Publications 28
#1Jon Waldron (UCL: University College London)H-Index: 1
#2Meryem Grabski (UCL: University College London)H-Index: 4
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Abstract Background Online sampling is widely used to recruit hard to reach samples such as drug users at nightlife events. We conducted the first study comparing differences in demographics, drug use and nightlife behaviour between an online sample of young adults engaging with the European nightlife scene, and an offline sample recruited at nightclubs and festivals in Europe. Methods Online participants who attended at least six nightlife events in the past 12 months were recruited using socia...
#1Will LawnH-Index: 11
#2Claire MokryszH-Index: 10
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#1Claire Mokrysz (UCL: University College London)H-Index: 10
#2Natacha D C Shaban (UCL: University College London)H-Index: 3
Last. Cja Morgan (UCL: University College London)H-Index: 38
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BACKGROUND: Acute cannabis administration can produce transient psychotic-like effects in healthy individuals. However, the mechanisms through which this occurs and which factors predict vulnerability remain unclear. We investigate whether cannabis inhalation leads to psychotic-like symptoms and speech illusion; and whether cannabidiol (CBD) blunts such effects (study 1) and adolescence heightens such effects (study 2). METHODS: Two double-blind placebo-controlled studies, assessing speech illus...
#1Suzanne H. Gage (University of Liverpool)H-Index: 20
#2Hannah H Sallis (UoB: University of Bristol)
Last. Marcus R. Munafò (UoB: University of Bristol)H-Index: 72
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Objectives: Observational epidemiological studies have found associations between smoking and both poorer cognitive ability and lower educational attainment; however, evaluating causality is more challenging. We used two complementary methods to attempt to ascertain whether smoking causes poorer cognitive ability and lower educational attainment. Design: A cohort study (Study One) and a two-sample Mendelian randomization study using publicly-available summary statistics (Study Two). Setting: The...
#1Abigail M. Freeman (UCL: University College London)H-Index: 4
#2Katherine Petrilli (UCL: University College London)H-Index: 2
Last. Tom P. Freeman (UCL: University College London)H-Index: 24
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Abstract The recent liberalisation of cannabis regulation has increased public and scientific debate about its potential benefits and risks. A key focus has been the extent to which cannabidiol (CBD) might influence the acute effects of delta-9-tetrahydrocannabinol (THC), but this has never been reviewed systematically. In this systematic review of how CBD influences the acute effects of THC we identified 16 studies involving 466 participants. Ten studies were judged at low risk of bias. The fin...
9 CitationsSource
#1Matthew B. Wall (UCL: University College London)H-Index: 22
#2Rebecca A Pope (UCL: University College London)H-Index: 6
Last. Valerie Curran (UCL: University College London)H-Index: 9
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Background:Two major constituents of cannabis are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the main psychoactive component; CBD may buffer the user against the harmful effects of THC.Aims:We examined the effects of two strains of cannabis and placebo on the human brain’s resting-state networks using fMRI.Methods:Seventeen healthy volunteers (experienced with cannabis, but not regular users) underwent three drug treatments and scanning sessions. Treatments were cannabis contain...
5 CitationsSource
#1Hina Akram (UCL: University College London)H-Index: 1
#2Claire Mokrysz (UCL: University College London)H-Index: 10
Last. H. Valerie Curran (UCL: University College London)H-Index: 34
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Background:Synthetic cannabinoids are, typically, full agonists at the cannabinoid CB1 receptor, and therefore considerably more potent than natural cannabis and may have correspondingly more serio...
2 CitationsSource
#1Valerie CurranH-Index: 9
#2Claire MokryszH-Index: 10
Last. Cja MorganH-Index: 38
view all 7 authors...
#1Claire Mokrysz (UCL: University College London)H-Index: 10
#2Tom P. Freeman (UCL: University College London)H-Index: 24
1 CitationsSource
#1Tom P. Freeman (UCL: University College London)H-Index: 24
#2Rebecca A Pope (UCL: University College London)H-Index: 6
Last. H. Valerie Curran (UCL: University College London)H-Index: 34
view all 13 authors...
Background: Despite the current shift towards permissive cannabis policies, few studies have investigated the pleasurable effects users seek. Here, we investigate the effects of cannabis on listening to music, a rewarding activity that frequently occurs in the context of recreational cannabis use. We additionally tested how these effects are influenced by cannabidiol, which may offset cannabis-related harms. Methods: Across 3 sessions, 16 cannabis users inhaled cannabis with cannabidiol, cannabi...
4 CitationsSource