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Claire Mokrysz
University College London
23Publications
9H-index
2,511Citations
Publications 23
Newest
#1Abigail M. Freeman (UCL: University College London)
#2Katherine Petrilli (UCL: University College London)H-Index: 1
Last.Tom P. Freeman (UCL: University College London)H-Index: 20
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Abstract The recent liberalisation of cannabis regulation has increased public and scientific debate about its potential benefits and risks. A key focus has been the extent to which cannabidiol (CBD) might influence the acute effects of delta-9-tetrahydrocannabinol (THC), but this has never been reviewed systematically. In this systematic review of how CBD influences the acute effects of THC we identified 16 studies involving 466 participants. Ten studies were judged at low risk of bias. The fin...
#1Matthew B. Wall (UCL: University College London)H-Index: 19
#2Rebecca Anne Pope (UCL: University College London)H-Index: 3
Last.Abigail M. Freeman (UCL: University College London)
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Background:Two major constituents of cannabis are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the main psychoactive component; CBD may buffer the user against the harmful effects of THC.Aims:We examined the effects of two strains of cannabis and placebo on the human brain’s resting-state networks using fMRI.Methods:Seventeen healthy volunteers (experienced with cannabis, but not regular users) underwent three drug treatments and scanning sessions. Treatments were cannabis contain...
#1Hina Akram (UCL: University College London)H-Index: 1
#2Claire Mokrysz (UCL: University College London)H-Index: 9
Last.H. Valerie Curran (UCL: University College London)H-Index: 41
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Background:Synthetic cannabinoids are, typically, full agonists at the cannabinoid CB1 receptor, and therefore considerably more potent than natural cannabis and may have correspondingly more serious psychological effects. Despite government sanctions against their production they continue to be available in ever-increasing varieties over the Internet. The psychological consequences of synthetic cannabinoid use are relatively unknown.Aim:The purpose of this study was to synthesise the available ...
#1Tom P. Freeman (UCL: University College London)H-Index: 20
#2Rebecca Anne Pope (UCL: University College London)H-Index: 3
Last.Michael A P Bloomfield (UCL: University College London)H-Index: 8
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Background: Despite the current shift towards permissive cannabis policies, few studies have investigated the pleasurable effects users seek. Here, we investigate the effects of cannabis on listening to music, a rewarding activity that frequently occurs in the context of recreational cannabis use. We additionally tested how these effects are influenced by cannabidiol, which may offset cannabis-related harms. Methods: Across 3 sessions, 16 cannabis users inhaled cannabis with cannabidiol, cannabi...
#1Amanda Sinai (UCL: University College London)H-Index: 5
#2Claire Mokrysz (UCL: University College London)H-Index: 9
Last.Richard Hillier (Camden and Islington NHS Foundation Trust)H-Index: 1
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BACKGROUND: People with Down syndrome (DS) are an ultra-high risk population for Alzheimer's disease (AD). Understanding the factors associated with age of onset and survival in this population could highlight factors associated with modulation of the amyloid cascade. OBJECTIVE: This study aimed to establish the typical age at diagnosis and survival associated with AD in DS and the risk factors associated with these. METHODS: Data was obtained from the Aging with Down Syndrome and Intellectual D...
#1Sally Adams (University of Bath)H-Index: 7
#2Claire Mokrysz (UCL: University College London)H-Index: 9
Last.Marcus R. MunafòH-Index: 63
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Impaired response inhibition is an important factor in tobacco dependence. We examined the effects of inhibitory control training (ICT) on inhibition, smoking resistance and cigarette use. Smokers (n = 55) abstained from smoking for 12 h prior to testing. On the test day, participants recorded cigarette use and completed pre-training measures of global and cue-specific (smoking-related) response inhibition. Participants were randomized to either an active or a control ICT group. The active group...
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