Wai Tong Ng
Pamela Youde Nethersole Eastern Hospital
Publications 74
#1Anne W.M. Lee (HKU: University of Hong Kong)H-Index: 30
#2Wai Tong Ng (Pamela Youde Nethersole Eastern Hospital)H-Index: 20
Last.Cai Grau (Aarhus University Hospital)H-Index: 45
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Abstract Purpose The treatment of nasopharyngeal carcinoma (NPC) requires high radiation doses. The balance of the risks of local recurrence due to inadequate tumor coverage versus the potential damage to the adjacent organs at risk (OARs) is of critical importance. With advancements in technology, high target conformality is possible. Nonetheless, to achieve the best possible dose distribution, optimal setting of dose targets and dose prioritization for tumor volumes and various OARs is fundame...
#1Wai Tong Ng (Pamela Youde Nethersole Eastern Hospital)H-Index: 20
#2Michael Ch Lee (Pamela Youde Nethersole Eastern Hospital)
Last.C.L. Chiang (HKU: University of Hong Kong)H-Index: 4
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#1Wai Tong Ng (Pamela Youde Nethersole Eastern Hospital)H-Index: 20
#2Edwin C Y Wong (Pamela Youde Nethersole Eastern Hospital)
Last.Victor Ho Fun Lee (HKU: University of Hong Kong)H-Index: 15
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#1Luo Chen (Hong Kong Baptist University)
#2Lai‑Sheung Chan (Hong Kong Baptist University)H-Index: 1
Last.GeorgeSai-WahTsao (HKU: University of Hong Kong)H-Index: 19
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Abstract Background Sulforaphane (SFN), a natural compound present in cruciferous vegetable, has been shown to possess anti-cancer activities. Cancer stem cell (CSC) in bulk tumor is generally considered as treatment resistant cell and involved in cancer recurrence. The effects of SFN on nasopharyngeal carcinoma (NPC) CSCs have not yet been explored. Purpose The present study aims to examine the anti-tumor activities of SFN on NPC cells with CSC-like properties and the underlying mechanisms. Met...
#1Anne W.M. Lee (HKU: University of Hong Kong)H-Index: 30
#2Wai Tong Ng (Pamela Youde Nethersole Eastern Hospital)H-Index: 20
Last.Primož StrojanH-Index: 23
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Abstract As a consequence of the current excellent loco-regional control rates attained using the generally accepted treatment paradigms involving intensity-modulated radiotherapy for nasopharyngeal carcinoma (NPC), only 10-20% of patients will suffer from local and/or nodal recurrence after primary treatment. Early detection of recurrence is important as localized recurrent disease is still potentially salvageable, but this treatment often incurs a high risk of major toxicities. Due to the poss...
#1Nelson Tsz Cheong Fung (Pamela Youde Nethersole Eastern Hospital)
#2Wai Man HungH-Index: 4
Last.Wai Tong NgH-Index: 20
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Abstract The aim of this study was to quantify the geometrical differences between manual contours and autocontours, the dosimetric impacts, and the time gain of using autosegmentation in adaptive nasopharyngeal carcinoma (NPC) intensity-modulated radiotherapy (IMRT) for a commercial system. A total of 20 consecutive Stages I to III NPC patients who had undergone adaptive radiation therapy (ART) re planning for IMRT treatment were retrospectively studied. Manually delineated organs at risks (OAR...