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Michael Gowen
New York University
ImmunologyMelanomaToxicityMedicineBiomarker (medicine)
4Publications
2H-index
36Citations
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Publications 4
Newest
#1Danny Simpson (NYU: New York University)H-Index: 5
#2Robert Ferguson (NYU: New York University)H-Index: 5
Last. Tomas Kirchhoff (NYU: New York University)H-Index: 15
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#1Michael Gowen (NYU: New York University)H-Index: 2
#2Keith M. Giles (NYU: New York University)H-Index: 23
Last. Iman Osman (NYU: New York University)H-Index: 49
view all 14 authors...
Immune checkpoint inhibitors (anti-CTLA-4, anti-PD-1, or the combination) enhance anti-tumor immune responses, yielding durable clinical benefit in several cancer types, including melanoma. However, a subset of patients experience immune-related adverse events (irAEs), which can be severe and result in treatment termination. To date, no biomarker exists that can predict development of irAEs. We hypothesized that pre-treatment antibody profiles identify a subset of patients who possess a sub-clin...
12 CitationsSource
#1Michael Gowen (NYU: New York University)H-Index: 2
#2Jeremy Tchack (NYU: New York University)H-Index: 3
Last. Iman Osman (NYU: New York University)H-Index: 49
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9559Background: There are no predictive biomarkers of ipilimumab (IPI) toxicity. Of metastatic melanoma (MM) patients (pts) receiving IPI (3mg/kg), 35% require systemic therapies to treat immune-re...
1 CitationsSource
#1Marianna Vitiello (UniPi: University of Pisa)H-Index: 5
#2Andrea Tuccoli (UniPi: University of Pisa)H-Index: 6
Last. Laura Poliseno (UniPi: University of Pisa)H-Index: 1
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// Marianna Vitiello 1, 2 , Andrea Tuccoli 1 , Romina D’Aurizio 3 , Samanta Sarti 1, 4 , Laura Giannecchini 1 , Simone Lubrano 1, 4 , Andrea Marranci 1, 4 , Monica Evangelista 2 , Silvia Peppicelli 5 , Chiara Ippolito 6 , Ivana Barravecchia 7 , Elena Guzzolino 7 , Valentina Montagnani 8 , Michael Gowen 9 , Elisa Mercoledi 1 , Alberto Mercatanti 2 , Laura Comelli 2 , Salvatore Gurrieri 1 , Lawrence W. Wu 10 , Omotayo Ope 10 , Keith Flaherty 11 , Genevieve M. Boland 11 , Marc R. Hammond 11 , Lawre...
23 CitationsSource
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