Yong Xu
Shanxi Medical University
Single-nucleotide polymorphismGenetic associationGeneticsSchizophreniaBiology
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Publications 3
#1Chuanjun ZhuoH-Index: 8
#2Yong Xu (Shanxi Medical University)H-Index: 5
Last. Chunhua Zhou (Hebei Medical University)H-Index: 1
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Few studies have been conducted to explore the influence of the COMT genotype on the severity and treatment effect of auditory verbal hallucinations symptoms (AVHs) in healthy individuals with AVHs (H-AVHs) subjects. We hypothesized that the effect of dopamine antagonist treatment on AVHs in H-AVHs may be influenced by their catechol-o-methyl transferase (COMT) genotype and may be accompanied by corresponding brain alterations. To preliminary investigate and test our hypothesis in an artificiall...
#1Wei Zhou (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Yong Xu (Shanxi Medical University)H-Index: 5
Last. Shengying Qin (Guangzhou Medical University)H-Index: 19
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Olanzapine is a second-generation antipsychotic medication, which plays a predominant role in current treatment of schizophrenia. It has been observed that the olanzapine response in schizophrenia treatment is different across individuals. However, predicting such individual-specific olanzapine response requires deep understanding of relevant biomarkers. Here, we performed an integrative investigation on 238 Han Chinese schizophrenia patients, aiming to identifying hidden predictive biomarkers t...
1 CitationsSource
#1Chuanjun ZhuoH-Index: 8
#2Yong Xu (Shanxi Medical University)H-Index: 5
Last. Rachel Upthegrove (University of Birmingham)H-Index: 14
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Background: Antipsychotic drugs may lead to side effects such as obesity, diabetes, dyslipidemia, and cardiovascular disease. The current systematic review and network meta-analysis analyzes and provides an update on the clinical performance of these add-ons in comparison to placebo on body weight and body mass index (BMI) reductions. Methods: A comprehensive literature search was performed on electronic databases: PubMed (1946-), Embase (1974-), Cochrane library (1992-), and OpenGrey (2000-) un...