Vincent Moutardier
Aix-Marseille University
Publications 135
#1Nausicaa Malissen (AMU: Aix-Marseille University)H-Index: 4
#2Nicolas Macagno (AMU: Aix-Marseille University)H-Index: 4
Last.Christine Pasero (AMU: Aix-Marseille University)H-Index: 6
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ABSTRACTHVEM (Herpes Virus Entry Mediator) engagement of BTLA (B and T Lymphocyte Attenuator) triggers inhibitory signals in T cells and could play a role in evading antitumor immunity. Here, HVEM ...
#1Gwen Lomberk (MCW: Medical College of Wisconsin)H-Index: 26
#2Yuna BlumH-Index: 4
Last.Nabila ElarouciH-Index: 10
view all 33 authors...
Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although there remains a lack of knowledge regarding the underlying epigenomics of PDAC. Here we perform multi-parametric integrative analyses of chromatin immunoprecipitation-sequencing (ChIP-seq) on multiple histone modifications, RNA-sequencing (RNA-seq), and DNA methylation to define epigenomic landscapes for PDAC subtypes, which can predict their relativ...
#1Louise Barbier (AMU: Aix-Marseille University)H-Index: 11
#2Diane Mege (AMU: Aix-Marseille University)H-Index: 9
Last.Jean Robert Delpero (AMU: Aix-Marseille University)H-Index: 30
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#1Lysa Marie (AMU: Aix-Marseille University)H-Index: 1
#2Robin Nacache (AMU: Aix-Marseille University)
Last.Thierry Bège (AMU: Aix-Marseille University)H-Index: 11
view all 9 authors...
Purpose During Roux-en-Y-gastric Bypass, the limb lengths are preoperatively determined regardless of individual small bowel length (SBL), which presents a great variability. Few studies highlighted anthropometric factors associated with SBL, and none attempted to predict SBL preoperatively.
#1Théophile Guilbaud (AMU: Aix-Marseille University)H-Index: 2
#2David Jérémie Birnbaum (AMU: Aix-Marseille University)H-Index: 6
Last.Vincent Moutardier (AMU: Aix-Marseille University)H-Index: 29
view all 8 authors...
Background Postoperative pancreatic fistula and pancreas-specific complications have a significant influence on patient management and outcomes after pancreatoduodenectomy. The aim of the study was to assess the value of serum C-reactive protein on the postoperative day 1 as early predictor of pancreatic fistula and pancreas-specific complications.
#1Orianne OlivaresH-Index: 4
#2Jared R. MayersH-Index: 13
Last.Patrice BerthezeneH-Index: 20
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Cancer cells adapt their metabolism to survive limited nutrient availability. Here, the authors show that in conditions of limited glucose or glutamine availability, pancreatic ductal adenocarcinoma cells can use collagen-derived proline to foster the TCA cycle and allow…
#1Théophile Guilbaud (AMU: Aix-Marseille University)H-Index: 2
#2David Jérémie Birnbaum (AMU: Aix-Marseille University)H-Index: 6
Last.Vincent Moutardier (AMU: Aix-Marseille University)H-Index: 29
view all 9 authors...
Background Delayed gastric emptying (DGE) is the most frequent pancreatic specific complication (PSC) after pancreaticoduodenectomy (PD). Several gastric decompression systems exist to manage DGE. Patients with a pancreatic tumor require prolonged nutrition; however, controversies exist concerning nutrition protocol after PD. The aim of the study was to assess the safety and efficacy of nasogastric (NG), gastrostomy (GT), and gastrojejunostomy (GJ) tubes with different feeding systems on postope...
#1David Jérémie Birnbaum (AMU: Aix-Marseille University)H-Index: 6
#2Pascal Finetti (AMU: Aix-Marseille University)H-Index: 42
Last.Emilie Mamessier (AMU: Aix-Marseille University)H-Index: 20
view all 11 authors...
Abstract Background Pancreatic carcinoma is one of the most lethal human cancers. In patients with resectable tumors, surgery followed by adjuvant chemotherapy is the only curative treatment. However, the 5-year survival is 20%. Because of a strong metastatic propensity, neoadjuvant chemotherapy is being tested in randomized clinical trials. In this context, improving the selection of patients for immediate surgery or neoadjuvant chemotherapy is crucial, and high-throughput molecular analyses ma...