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Vincent Moutardier
Aix-Marseille University
CancerSurgeryAdenocarcinomaGeneral surgeryMedicine
136Publications
30H-index
3,284Citations
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Publications 161
Newest
#1Charles Vanbrugghe (AMU: Aix-Marseille University)
#2David Jérémie Birnbaum (AMU: Aix-Marseille University)H-Index: 5
Last. Vincent Moutardier (AMU: Aix-Marseille University)H-Index: 30
view all 8 authors...
PURPOSE: We evaluated the intuition of expert pancreatic surgeons, in predicting the associated risk of pancreatic resection and compared this "intuition" to actual operative follow-up. The objective was to avoid major complications following pancreatic resection, which remains a challenge. METHODS: From January 2015 to February 2018, all patients who were 18 years old or more undergoing a pancreatic resection (pancreaticoduodenectomy [PD], distal pancreatectomy [DP], or central pancreatectomy [...
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#1Rémy NicolleH-Index: 8
#2Yuna BlumH-Index: 4
Last. Marion RubisH-Index: 4
view all 25 authors...
BACKGROUND: A significant gap in pancreatic ductal adenocarcinoma (PDAC) patients care is the lack of molecular parameters characterizing tumors and allowing a personalized treatment. The goal of this study was to examine whole PDAC transcriptomic profiles to define a signature that would predict aggressiveness and treatment responsiveness better than done until now. METHODS AND PATIENTS: Tumors were obtained from 76 consecutive resectable (n=40) or unresectable (n=36) tumors. PDAC were transpla...
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#1Nicolas RegenetH-Index: 22
#1N. RegenetH-Index: 6
Last. Patrick PessauxH-Index: 44
view all 13 authors...
Summary Objective To assess the value of 18F-FDG PET/CT in differentiating between benign and malignant intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Summary background data Malignant or high-risk IPMN require surgical resection but surgery should be avoided in patients with IPMN carrying a low risk of malignancy. 18F-FDG PET has been studied mostly in small, single center, retrospective series. Methods Prospective, non-comparative, multicenter French study. The primary endpoi...
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#1N. RegenetH-Index: 6
#1Nicolas RegenetH-Index: 22
Last. Patrick PessauxH-Index: 44
view all 13 authors...
Resume Objectifs Evaluation de la valeur du PET scanner au 18F-FDG dans la differenciation des formes benignes et malignes des tumeurs intracanalaires papillaire et mucineuse du pancreas. Introduction Les TIPMP malignes ou de haut risque necessitent une resection chirurgicale mais cette chirurgie devrait etre evitee en cas de TIPMP a faible risque de malignite. Le PET scanner au 18F-FDG a ete etudie dans de nombreuses series retrospectives monocentriques. Methode Il s’agit d’une etude multicentr...
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#1T. Delayre (AMU: Aix-Marseille University)
#2Théophile Guilbaud (AMU: Aix-Marseille University)H-Index: 3
Last. David Jérémie Birnbaum (AMU: Aix-Marseille University)H-Index: 5
view all 10 authors...
BACKGROUND: The prognosis of patients with pancreatic cancer remains poor and novel therapeutic targets are required urgently. Treatment resistance could be due to the tumour microenvironment, a desmoplastic stroma consisting of cancer-associated fibroblasts and tumour-infiltrating lymphocytes (TILs). The aim of the study was to evaluate the prognostic value of TILs and cancer-associated fibroblasts (CAFs) in pancreatic cancer of the body and tail. METHODS: Using tissue microarray from resected ...
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#1N. Malissen (AMU: Aix-Marseille University)H-Index: 5
#2Nicolas Macagno (AMU: Aix-Marseille University)H-Index: 6
Last. Daniel Olive (AMU: Aix-Marseille University)H-Index: 16
view all 14 authors...
ABSTRACTHVEM (Herpes Virus Entry Mediator) engagement of BTLA (B and T Lymphocyte Attenuator) triggers inhibitory signals in T cells and could play a role in evading antitumor immunity. Here, HVEM ...
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#1Marta SandiniH-Index: 4
#1Marta SandiniH-Index: 9
Last. Luca GianottiH-Index: 35
view all 16 authors...
Objective:To analyze possible associations between the duration of stent placement before surgery and the occurrence and severity of postoperative complications after pancreatoduodenectomy (PD).Background:The effect of preoperative stent duration on postoperative outcomes after PD has not been inves
7 CitationsSource
#1Marta SandiniH-Index: 9
#2Kim C. HonselmannH-Index: 6
Last. Luca GianottiH-Index: 35
view all 9 authors...
Source
#1Aurélie MaignanH-Index: 4
#2Mehdi OuaissiH-Index: 21
Last. Igor SielezneffH-Index: 21
view all 12 authors...
Resume La prise en charge des consequences fonctionnelles apres exerese pancreatique est devenue un nouvel enjeu therapeutique. L’objectif de notre etude est d’evaluer l’ensemble des facteurs de risques d’insuffisance pancreatique exocrine (IPExo) et d’insuffisance pancreatique endocrine (IPEndo) apres chirurgie pancreatique et d’etablir un modele predictif de survenue de ces insuffisances. Materiel et methode Entre le 1/01/14 et le 19/06/15, 91 malades consecutifs et suivis de maniere prospecti...
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#1Aurélie MaignanH-Index: 4
#2Mehdi OuaissiH-Index: 21
Last. Igor SielezneffH-Index: 21
view all 12 authors...
Summary Management of functional consequences after pancreatic resection has become a new therapeutic challenge. The goal of our study is to evaluate the risk factors for exocrine (ExoPI) and endocrine (EndoPI) pancreatic insufficiency after pancreatic surgery and to establish a predictive model for their onset. Patients and methods Between January 1, 2014 and June 19, 2015, 91 consecutive patients undergoing pancreatoduodenectomy (PD) or left pancreatectomy (LP) (72% and 28%, respectively) were...
5 CitationsSource
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