Nada Bozina
University Hospital Centre Zagreb
GenotypePsychologyAlleleClinical psychologyMedicine
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Publications 42
#2Nada Bozina (University Hospital Centre Zagreb)H-Index: 12
Last. Martina Rojnic Kuzman (University Hospital Centre Zagreb)H-Index: 13
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Our aim was to analyze the association of HSPA1B genotypes and treatment response measured by the changes of psychopathology and neurocognitive symptoms in patients with first-episode psychosis (FEP) after 18 months of treatment. A sample of 159 patients with FEP admitted at two Croatian psychiatric hospitals in the period between year 2014 and year 2017 was assessed at baseline and after 18 months of follow-up with Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schiz...
Clopidogrel is still widely used in acute coronary syndrome despite the development of more potent P2Y12 inhibitors. Previously, we conducted a trial that evaluated serial clopidogrel dose adjustment based on platelet function testing in acute coronary syndrome patients with initial high on-treatment platelet reactivity (HTPR). In this substudy, we performed post hoc analysis of the effect of ABCB1 genetic variants C3435T and G2677T/A on platelet inhibition and outcomes. There were no difference...
#1Maja Zivkovic (University Hospital Centre Zagreb)H-Index: 7
#2Alma Mihaljević-Peleš (University of Zagreb)H-Index: 16
Last. Nada Bozina (University Hospital Centre Zagreb)H-Index: 12
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BACKGROUND: Symptomatic remission is an achievable goal in the treatment of schizophrenia. The type of antipsychotic medication and particular genetic variants of the dopaminergic system might be associated with remission. Potential pharmacogenetic markers of the treatment response to antipsychotic medication are missing. This study assessed the possible association between dopamine receptor type 2 (DRD2 rs1800497) and dopamine transporter (DAT1 rs28363170) gene variants with symptomatic remissi...
#1Natasa Pejanovic-Skobic (University Clinical Hospital Mostar)H-Index: 2
#2Ivana Markovic (Clinical Hospital Dubrava)
Last. Silvio Basic (Clinical Hospital Dubrava)H-Index: 2
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Abstract Objective We assessed the influence of the SCN2A gene polymorphism c.56 G > A rs17183814 on the response to lamotrigine monotherapy in patients with focal epilepsy in Herzegovina area, Bosnia and Herzegovina. Material and methods For SCN2A polymorphism c.56 G > A rs17183814, one hundred patients with epilepsy who were receiving lamotrigine in monotherapy and seventy-one age and sex matched healthy controls were genotyped using TaqMan assay. All patients were Caucasians from the region o...
#1Martina Rojnic Kuzman (University Hospital Centre Zagreb)H-Index: 13
Last. Nada Bozina (University Hospital Centre Zagreb)H-Index: 12
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Abstract Introduction We analyzed the association of cannabinoid receptor CNR1 genotypes with changes in neurocognitive performance in patients with first-episode psychosis (FEP) after 18 months of treatment. Our secondary aim was to analyze the association of CNR1 genotypes with changes of perceived levels of stress. Methods We enrolled a sample of 159 patients with FEP from two Croatian psychiatric hospitals between 2014 and 2017. Patients were assessed at baseline and after 18 months. We anal...
2 CitationsSource
#1Sabina KucukalicH-Index: 2
#3HerzegovinaH-Index: 1
Last. Alma Dzubur KulenovicH-Index: 2
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BACKGROUND: Exposure to life-threatening events is common and everyone will most likely experience this type of trauma during their lifetime. Reactions to these events are highly heterogeneous and seems to be influenced by genes as well. Some individuals will develop posttraumatic stress disorder (PTSD), while others will not. In this study, our aim was to analyze the correlation between single nucleotide polymorphisms (SNPs) within the oxytocin receptor (OXTR) gene (rs53576 and rs2254298), the ...
1 CitationsSource
#1Nermina KravicH-Index: 2
#3HerzegovinaH-Index: 1
Last. Esmina AvdibegovicH-Index: 8
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BACKGROUND: The aim of this study is to investigate the association of gene variations of the monoamine oxidase A (MAOA) and the serotonin transporter solute carrier family 6 member 4 (SLC6A4) gene with posttraumatic stress disorder (PTSD) severity and coping strategies in patients with war related PTSD. SUBJECTS AND METHODS: The study included 747 individuals who had experienced war trauma in the South Eastern Europe conflicts between 1991 and 1999. Genotyping of the MAOA VNTR and SLC6A4 tandem...
#1Nenad Jakšić (University Hospital Centre Zagreb)H-Index: 10
Last. HerzegovinaH-Index: 1
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BACKGROUND: Posttraumatic stress disorder (PTSD) is a highly frequent and disabling psychiatric condition among war-affected populations. The FK506-binding protein 5 (FKBP5) gene and the corticotropin-releasing hormone receptor 1 (CRHR1) gene have previously been implicated in an elevated risk of peritraumatic dissociation and PTSD development. Our aim was to investigate the association between FKBP5 and CRHR1 genotypes and PTSD diagnosis and severity among individuals who were affected by the B...
2 CitationsSource
#1Aferdita Goci UkaH-Index: 2
#3Ferid AganiH-Index: 2
Last. HerzegovinaH-Index: 1
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BACKGROUND: Post-traumatic stress disorder (PTSD) is a stress related disorder which can occur in an individual after exposure to a traumatic event. It most commonly co-occurs with depression. The two disorders share not only overlapping symptoms, but also genetic diathesis. The aim of this study was to investigate the potential role of single nucleotide polymorphisms (SNPs) of the two serotonergic candidate genes 5-hydroxytryptamine receptor 1A (HTR1A) and tryptophan hydroxylase 2 (TPH2) in the...
1 CitationsSource
#1Martina Rojnic Kuzman (University of Zagreb)H-Index: 13
#2Porin MakaricH-Index: 2
Last. Zarko BajicH-Index: 3
view all 26 authors...
: The influence of cannabis use on the occurrence, clinical course and the treatment of the first psychotic episode (FEP) is well documented. However, the exact link is still not clearly established. The aim of this article is to review and report the noticed increase in the number of hospitalizations of young people with a clinical appearance of severe psychotic decompensation following cannabis consumption and to show the clinical challenges in treatment of the FEP. The case study describes th...
4 CitationsSource