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Yiyang Yuan
Chinese Academy of Sciences
6Publications
3H-index
29Citations
Publications 6
Newest
#1Yiyang Yuan (CAS: Chinese Academy of Sciences)H-Index: 3
#2Mei Li (CAS: Chinese Academy of Sciences)H-Index: 13
Last.Xinghui Qiu (CAS: Chinese Academy of Sciences)H-Index: 15
view all 4 authors...
2 CitationsSource
#1Dong Liu (CAS: Chinese Academy of Sciences)H-Index: 4
#2Kai Tian (CAS: Chinese Academy of Sciences)H-Index: 2
Last.Xinghui Qiu (CAS: Chinese Academy of Sciences)H-Index: 15
view all 6 authors...
Cytochrome P450s (CYPs or P450s) have been long recognized as very important enzymes in the metabolism of xenobiotic and endogenous compounds, but only a few CYPs have been functionally characterized in insects. The effort in functional characterization of insect P450s is heavily hindered by technical difficulties in preparing active, individual P450 enzymes directly from the target insect. In this paper, we describe the functional expression of two additional pyrethroid resistance-associated CY...
2 CitationsSource
#1Kai Tian (CAS: Chinese Academy of Sciences)H-Index: 2
#2Dong Liu (CAS: Chinese Academy of Sciences)H-Index: 4
Last.Xinghui Qiu (CAS: Chinese Academy of Sciences)H-Index: 15
view all 5 authors...
Abstract The cotton bollworm, Helicoverpa armigera , is a polyphagous pest that has a strong capacity to evolve resistance against various classes of insecticides. Cytochrome P450 enzymes have been suspected involved in pyrethroid metabolism and resistance in this pest. However, how many and which P450s are involved in pyrethroid metabolism is largely unknown. In this study, CYP6B6 and NADPH-cytochrome P450 reductase (HaCPR) from H. armigera were successfully co-expressed in Escherichia coli . I...
6 CitationsSource
#1J. ZhengH-Index: 1
#2Kai TianH-Index: 2
Last.Xinghui QiuH-Index: 15
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20-Hydroxyecdysone (20E) is a key hormone which regulates growth, development and reproduction in insects. Although cytochrome P450 enzymes (P450s) participating in the ecdysteroid biosynthesis of 20E have been characterized in a few model insects, no work has been published on the molecular entity of their orthologs in the cotton bollworm Helicoverpa armigera , a major pest insect in agriculture worldwide. In this study, four cytochrome P450 homologs, namely HarmCYP302A1, HarmCYP306A1, HarmCYP3...
3 CitationsSource
#1Dong Liu (CAS: Chinese Academy of Sciences)H-Index: 4
#2Yiyang Yuan (CAS: Chinese Academy of Sciences)H-Index: 3
Last.Xinghui Qiu (CAS: Chinese Academy of Sciences)H-Index: 15
view all 4 authors...
Quercetin is ubiquitous in terrestrial plants. The cotton bollworm Helicoverpa armigera as a highly polyphagous insect has caused severe crop losses. Until now, interactions between this pest and quercetin are poorly understood at the biochemical and molecular levels. In this study, we investigated the in vivo effects of quercetin on performance of cotton bollworm and on cytochrome P450 (P450) expression. Deleterious effects of quercetin on the performance of the cotton bollworm, including growt...
6 CitationsSource
#1Yiyang Yuan (CAS: Chinese Academy of Sciences)H-Index: 3
#2Xiaojie Zhou (CAS: Chinese Academy of Sciences)H-Index: 6
Last.Xinghui Qiu (CAS: Chinese Academy of Sciences)H-Index: 15
view all 5 authors...
Abstract T-2 toxin (T-2) is an acute toxic trichothecene mycotoxin produced mainly by Fusarium species, detected in many crops including oats, wheat and barley, in animal feed and food. It is important to know the metabolic pathway and kinetics of T-2 in food animals given that T-2 can cause serious adverse effects on human health. In this study, we investigated the metabolic capacity of chicken CYP3A37 in the metabolism of T-2 using reconstituted bacteria produced enzymes. Our results showed th...
10 CitationsSource
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