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Yanyan Chen
Academy of Medical Sciences, United Kingdom
Internal medicineEndocrinologyImpaired glucose toleranceDiabetes mellitusMedicine
11Publications
2H-index
34Citations
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Publications 12
Newest
#1Jinping WangH-Index: 8
#2Xiaoxia Shen (Academy of Medical Sciences, United Kingdom)H-Index: 1
Last. Guangwei Li (Academy of Medical Sciences, United Kingdom)H-Index: 11
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#1Xiaojue Li (Academy of Medical Sciences, United Kingdom)H-Index: 1
#2Jinping WangH-Index: 8
Last. Guangwei Li (Academy of Medical Sciences, United Kingdom)H-Index: 11
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1 CitationsSource
#1Yanyan ChenH-Index: 2
#2Ping ZhangH-Index: 38
Last. Guangwei LiH-Index: 11
view all 8 authors...
Responses to lifestyle interventions in people with impaired glucose tolerance (IGT) may differ during the intervention phase: some progress to diabetes, some regress to normal glucose tolerance (NGT) and some retain IGT. Whether these different responses to intervention influence subsequent outcomes is uncertain. In 1986, 576 persons with IGT in Da Qing, China, were randomized to control or intervention (diet, exercise, diet plus exercise) groups for a six-year lifestyle intervention. In 1992, ...
Source
#1Yali AnH-Index: 3
#2Ping ZhangH-Index: 38
Last. Guangwei LiH-Index: 11
view all 9 authors...
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#1Yuanchi Hui (Academy of Medical Sciences, United Kingdom)H-Index: 1
#2Jinping WangH-Index: 8
Last. Guangwei Li (Academy of Medical Sciences, United Kingdom)H-Index: 1
view all 10 authors...
Objective This study aimed to investigate premature mortality and the risk of cardiovascular disease (CVD) in Chinese adults with diabetes diagnosed before the age of 45 years.
1 CitationsSource
#2Chen Yanyan (Academy of Medical Sciences, United Kingdom)H-Index: 2
Last. Li Guang-wei (Academy of Medical Sciences, United Kingdom)H-Index: 1
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Type 2 diabetes represents an immense and growing public health challenge worldwide for its extremely high risk of blindness, renal failure, myocardial infarction and stroke. In the 1980s, it was unclear whether diabetes is preventable. Up to 2000, it remained unclear whether diabetes can be delayed over a long period by active lifestyle intervention and whether the benefits of diabetes prevention can extend to the prevention of diabetic vascular complications and the reduction of mortality. The...
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#2Yanyan ChenH-Index: 2
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Aims: To investigate the effects of lifestyle intervention on metabolism profile in people with impaired glucose tolerance (IGT), and potential biomarkers for prevention of diabetes. Methods: The study participants were identified as IGT by OGTT in 1986 and followed in 2006. Sixty participants were selected in the intervention group (I_Group) and 57 in control group (C_Group). UPLC-MS/MS analysis was performed by using the plasma samples. Principal component analysis and orthogonal partial least...
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#1Qiuhong GongH-Index: 2
#2Ping ZhangH-Index: 38
Last. Guangwei LiH-Index: 11
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Lifestyle interventions can prevent or delay type 2 diabetes (T2DM) but their long-term effect on cardiovascular disease (CVD) remains unclear. We assessed the effect of lifestyle interventions on the incidence of CVD events among Chinese adults with impaired glucose tolerance (IGT) who participated in the Da Qing Diabetes Prevention Study (DQDPS) and who were followed for up to 30 years after randomization. DQDPS was a 6-year clinical trial conducted in Da Qing, China from 1986 to 1992 in which...
Source
#1Xiaoxia Shen (Academy of Medical Sciences, United Kingdom)H-Index: 1
#2Ping Zhang (CDC: Centers for Disease Control and Prevention)H-Index: 38
Last. Guangwei Li (Academy of Medical Sciences, United Kingdom)H-Index: 11
view all 14 authors...
Background and aimWe sought to determine the effect of regression to normal glucose tolerance (NGT) or progression to diabetes in early years of impaired glucose tolerance (IGT) on subsequent risk ...
Source
#1Bo ZhangH-Index: 7
#2Yanyan ChenH-Index: 2
Last. Guang-wei LiH-Index: 1
view all 5 authors...
ObjectiveTo investigate the role of the acute glucagon response in the long-term remission of newly diagnosed type 2 diabetes mellitus following short-term intensive insulin therapy (IIT).MethodsTen patients with newly diagnosed type 2 diabetes mellitus received IIT. Intravenous glucose tolerance tests and the clamp technique were performed pre- and post-IIT. Remission was defined as maintenance of target glycaemic control without anti-diabetic agents for 1 year.ResultsThe remission rate was 50%...
2 CitationsSource
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