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Xiaoyan Wang
Shandong University
4Publications
2H-index
19Citations
Publications 4
Newest
Published on Sep 1, 2018in Cellular Signalling3.39
Ronghua Li2
Estimated H-index: 2
(SDU: Shandong University),
Meng Qiao2
Estimated H-index: 2
(SDU: Shandong University)
+ 3 AuthorsQing Sun2
Estimated H-index: 2
(SDU: Shandong University)
Abstract Psoriasis is a common immune-mediated chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation, differentiation and apoptosis. However, the exact etiology and pathogenesis are still unclear. Evidence is rapidly accumulating for the role of microRNAs in psoriasis. It has been demonstrated that Interleukin-22 (IL-22) plays vital role in T cell-mediated immune response by interacting with keratinocytes in the pathogenesis of psoriasis. The aim of our study was...
Published on Jun 1, 2018in Inflammation2.94
Xiaoyan Wang2
Estimated H-index: 2
(SDU: Shandong University),
Ronghua Li2
Estimated H-index: 2
(SDU: Shandong University)
+ 2 AuthorsQing Sun2
Estimated H-index: 2
(SDU: Shandong University)
Although metformin (MET) may be useful for the treatment of psoriasis, the mechanisms underlying its method of action have yet to be fully elucidated. Here, the relationship between MET function and reactive oxygen species (ROS) levels and the underlying mechanism were explored in human immortalized keratinocyte cell line (HaCaT). HaCaT cells were incubated with MET at 0, 10, 20, 40, and 60 mM for 24 h. The cell viability was evaluated by the CCK-8 assay. The cell apoptosis rate and intracellula...
Ronghua Li2
Estimated H-index: 2
(SDU: Shandong University),
Meng Qiao2
Estimated H-index: 2
(SDU: Shandong University)
+ 2 AuthorsQing Sun2
Estimated H-index: 2
(SDU: Shandong University)
Background The treatment of vitiligo is still one of the most difficult dermatological challenges, although there are many therapeutic options. Narrow band ultraviolet B (NB-UVB) phototherapy is considered to be a very important modality for generalized vitiligo. Objective The aim of this study was to explore whether a combination of NB-UVB and topical agents would be superior to NB-UVB alone for treating vitiligo. Methods We searched the electronic databases such as PUBMED, EMBASE, Cochrane Lib...
Published on Mar 8, 2016in Inflammation2.94
Xiaoyan Wang2
Estimated H-index: 2
(SDU: Shandong University),
Chengxiao Liu1
Estimated H-index: 1
(SDU: Shandong University),
Gongming Wang1
Estimated H-index: 1
(SDU: Shandong University)
High-mobility group box 1 (HMGB1) plays a key role in the development of acute lung injury (ALI). Propofol, a general anesthetic with anti-inflammatory properties, has been suggested to be able to modulate lipopolysaccharide (LPS)-induced ALI. In this study, we investigated the effects of propofol on the expression of HMGB1 in a rat model of LPS-induced ALI. Rats underwent intraperitoneal injection of LPS to mimic sepsis-induced ALI. Propofol bolus (1, 5, or 10 mg/kg) was infused continuously 30...
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