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Mingju Hao
Academy of Medical Sciences, United Kingdom
AntibodyEpitopeImmunologyCatumaxomabBlinatumomab
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#1Gaowei Fan (Academy of Medical Sciences, United Kingdom)H-Index: 1
#2Zujian WangH-Index: 2
Last. Jinming Li (Academy of Medical Sciences, United Kingdom)H-Index: 1
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Bispecific antibodies (BsAbs) recognize two different epitopes. This dual specificity opens up a wide range of applications, including redirecting T cells to tumor cells, blocking two different signaling pathways simultaneously, dual targeting of different disease mediators, and delivering payloads to targeted sites. The approval of catumaxomab (anti-EpCAM and anti-CD3) and blinatumomab (anti-CD19 and anti-CD3) has become a major milestone in the development of bsAbs. Currently, more than 60 dif...
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