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Mingju Hao
Academy of Medical Sciences, United Kingdom
2Publications
2H-index
95Citations
Publications 2
Newest
Published on Dec 1, 2015in Journal of Hematology & Oncology8.73
Gaowei Fan1
Estimated H-index: 1
(Academy of Medical Sciences, United Kingdom),
Zujian Wang2
Estimated H-index: 2
+ 1 AuthorsJinming Li1
Estimated H-index: 1
(Academy of Medical Sciences, United Kingdom)
Bispecific antibodies (BsAbs) recognize two different epitopes. This dual specificity opens up a wide range of applications, including redirecting T cells to tumor cells, blocking two different signaling pathways simultaneously, dual targeting of different disease mediators, and delivering payloads to targeted sites. The approval of catumaxomab (anti-EpCAM and anti-CD3) and blinatumomab (anti-CD19 and anti-CD3) has become a major milestone in the development of bsAbs. Currently, more than 60 dif...
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