Kenneth F. Adams
National Institutes of Health
CancerBody mass indexWeight gainMedicineRelative risk
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Publications 19
Using data from the National Institutes of Health-AARP Diet and Health Study, we evaluated the influence of adulthood weight history on mortality risk. The National Institutes of Health-AARP Diet and Health Study is an observational cohort study of US men and women who were aged 50–71 years at entry in 1995–1996. This analysis focused on 109,947 subjects who had never smoked and were younger than age 70 years. We estimated hazard ratios of total and cause-specific mortality for recalled body mas...
81 CitationsSource
kg/m 2 increase, hazard ratio (HR) = 1.18, 95% confidence interval (CI): 1.11, 1.25), at age 50 years (HR = 1.18, 95% CI: 1.10, 1.26), and at age 35 years (HR = 1.16, 95% CI: 1.07, 1.25) but less so at age 18 years. Weight gained between the ages of 18 and 35 years and between 18 years of age and the baseline age was associated with an increased risk of colon cancer in men (per 0.5-kg/year increase, HR = 1.18, 95% CI: 1.11, 1.25 and HR = 1.29, 95% CI: 1.16, 1.56, respectively). For women, relati...
48 CitationsSource
#1Andrew FloodH-Index: 16
#2Andrew G RenehanH-Index: 52
Last. Arthur SchatzkinH-Index: 82
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#1Annemarie Koster (NIH: National Institutes of Health)H-Index: 46
Last. Tamara B. HarrisH-Index: 175
view all 7 authors...
Background Smoking and high adiposity are strong independent health risk factors but are also interrelated. Smoking is related to a lower body mass index (BMI) but not necessarily with a smaller waist circumference. Smoking cessation is associated with increased body weight and substantial increase in waist circumference. How this affects mortality risk is unknown.
55 CitationsSource
#1Kenneth F. Adams (Regions Hospital)H-Index: 12
#2Michael F. Leitzmann (NIH: National Institutes of Health)H-Index: 81
Last. Wong Ho Chow (NIH: National Institutes of Health)H-Index: 78
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Renal cell cancer (RCC) incidence has increased in the United States over the past three decades. The authors analyzed the association between body mass index (BMI) and invasive RCC in the National Institutes of Health (NIH)–AARP Diet and Health Study, a large, prospective cohort aged 50–71 years at baseline initiated in 1995–1996, with follow-up through December 2003. Detailed analyses were conducted in a subcohort responding to a second questionnaire, including BMI at younger ages (18, 35, and...
106 CitationsSource
#1Steven C. Moore (NIH: National Institutes of Health)H-Index: 41
#2Wong Ho ChowH-Index: 78
Last. Michael F. Leitzmann (NIH: National Institutes of Health)H-Index: 81
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Evidence for a relation between physical activity and renal cell cancer has been inconsistent. The authors examined physical activity in relation to renal cell cancer in a large, prospective US cohort study of 482,386 participants (289,503 men and 192,883 women) aged 50–71 years at baseline (1995–1996). At baseline, participants reported their frequency of exercise of at least 20 minutes' duration, intensity of daily routine activity, and frequency of physical activity during adolescence. During...
42 CitationsSource
#1Annemarie Koster (UM: Maastricht University)H-Index: 46
Last. Tamara B. Harris (NIH: National Institutes of Health)H-Index: 175
view all 8 authors...
The authors examined the association between waist circumference and mortality among 154,776 men and 90,757 women aged 51-72 years at baseline (1996-1997) in the NIH-AARP Diet and Health Study. Additionally, the combined effects of waist circumference and body mass index (BMI; weight (kg)/height (m) 2 ) were examined. All-cause mortality was assessed over 9 years of follow-up (1996-2005). After adjustment for BMI and other covariates, a large waist circumference (fifth quintile vs. second) was a...
155 CitationsSource
#1Rachael Z. Stolzenberg-Solomon (NIH: National Institutes of Health)H-Index: 57
#2Kenneth F. Adams (NIH: National Institutes of Health)H-Index: 12
Last. Debra T. Silverman (NIH: National Institutes of Health)H-Index: 70
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Obesity and lack of physical activity have been inconsistently associated with pancreatic cancer. Using data from a self-administered baseline questionnaire (1995-1996), the authors investigated the association between adiposity and physical activity and pancreatic cancer in 495,035 participants of the National Institutes of Health-AARP Diet and Health Study who were aged 50-71 years. To avoid the influence of subclinical disease, follow-up time started 1 year after baseline, and subjects with a...
90 CitationsSource
#1Jiyoung AhnH-Index: 39
#2Arthur SchatzkinH-Index: 82
Last. Michael F. LeitzmannH-Index: 81
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Background Obesity is a risk factor for postmenopausal breast cancer, but the role of the timing and amount of adult weight change in breast cancer risk is unclear. Methods We prospectively examined the relations of adiposity and adult weight change to breast cancer risk among 99 039 postmenopausal women in the National Institutes of Health–AARP Diet and Health Study. Anthropometry was assessed by self-report in 1996. Through 2000, 2111 incident breast cancer cases were ascertained. Results Curr...
231 CitationsSource