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Ting Chen
Soochow University (Suzhou)
9Publications
2H-index
5Citations
Publications 9
Newest
#1Ting Chen (Soochow University (Suzhou))H-Index: 2
#2Linqi Chen (Soochow University (Suzhou))H-Index: 2
Last.Fei Xiao (Soochow University (Suzhou))
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Background. Central precocious puberty (CPP) is defined by gonadotropin-dependent development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. MKRN3 and DLK1 are two genes, disease-causing variants of which have recently been discovered to cause idiopathic CPP. Methods. We screened 173 Chinese patients (9 males and 164 females; 9 familial and 164 sporadic) with ICPP and 43 patients (9 males and 34 females; 3 familial and 40 sporadic) with early puberty ...
#1Ting Chen (Soochow University (Suzhou))H-Index: 2
#2Haiying Wu (Soochow University (Suzhou))H-Index: 1
Last.Hui Sun (Soochow University (Suzhou))H-Index: 1
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Background. Bone mineral density quantitative trait locus 18 (BMND18, OMIM #300910) is a type of early-onset osteogenesis imperfecta (OI) caused by loss-of-function mutations in the PLS3 gene, which encodes plastin-3, a key protein in the formation of actin bundles throughout the cytoskeleton. Here, we report a patient with PLS3 mutation caused BMND18 and evaluated all the reported disease-causing mutations by bioinformatic analysis. Methods. Targeted gene sequencing was performed to find the di...
#1Ting Chen (Soochow University (Suzhou))H-Index: 2
#2Dandan Zhang (Soochow University (Suzhou))
Last.Hui Sun (Soochow University (Suzhou))H-Index: 1
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Neonatal diabetes mellitus (NDM) is a rare monogenic disorder presenting as uncontrolled hyperglycemia during the first 6 months of life. Hyperglycemic hyperosmolar state (HHS) is quite rare in NDM patients, and reported experience with this condition is limited. Continuous renal replacement therapy (CRRT) is frequently used as a mode of dialytic treatment in critically ill patients with acute renal failure, but has seldom been used in patients with diabetic ketoacidosis (DKA) and HHS. We report...
#1Shuiyan Wu (Soochow University (Suzhou))
#2Ting Chen (Soochow University (Suzhou))H-Index: 2
Last.Zhenjiang Bai (Soochow University (Suzhou))H-Index: 3
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Abstract Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a rare autosomal recessive disease characterized by infancy-onset diaphragmatic palsy and symmetrical distal muscular weakness. SMARD1 is caused by loss-of-function mutations in IGHMBP2 gene. In this article, we report a male SMARD1 patient with two compound heterozygous mutations (NM_002180.2: c.688C > G; p.(Gln230Glu)) and (NM_002180.2: c.1737C > A; p.(Phe579Leu)), one of which (c.688C > G; ClinVar accession: SUB3344...
#1Fengyun Wang (Soochow University (Suzhou))H-Index: 2
#2Ting Chen (Soochow University (Suzhou))H-Index: 2
Last.Miao Hou (Soochow University (Suzhou))H-Index: 1
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Progranulin (PGRN), a novel peptide that has recently emerged as an important regulatory adipokine, is relevant to energy homeostasis and obesity in animals and adult humans. Little is known about its roles in children. The aim of the current study was to determine the potential role of PGRN and explore its relationship to various obesity-related markers in obese children. This was a cross-sectional study composed of 77 children (43 obese and 34 healthy, age 8.68 ± 0.28 and 8.46 ± 0.45 years, re...
#1Rongrong Xie (Soochow University (Suzhou))H-Index: 1
#2Linqi Chen (Soochow University (Suzhou))H-Index: 2
Last.Xiaozhong Li (Soochow University (Suzhou))
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Background. Gonadal injury following chemotherapy is of increasing importance with the continuous improvement of survival rates. The protection of gonadotropin hormone antagonist (GnRHant) in long-term adult survivors of adolescent cancers and some autoimmune diseases has not yet been evaluated. Methods. The present study was aimed at longitudinally exploring whether the GnRHant could alleviate testicular damage induced by cyclophosphamide (CPA) in a rat model. Pubertal male rats were assigned t...
#1Ting Chen (Soochow University (Suzhou))H-Index: 2
#2Haiying Wu (Soochow University (Suzhou))H-Index: 1
Last.Linqi Chen (Soochow University (Suzhou))H-Index: 2
view all 7 authors...
Abstract Study Objective To investigate the potential of serum anti-Mullerian hormone (AMH) and inhibin B (INHB) levels as markers for pubertal progression rate in girls with central precocious puberty (CPP). Design, Setting, Participants, Interventions, and Main Outcome Measures A total of 148 girls were enrolled, including 65 girls with premature thelarche and 83 girls with CPP, grouped on the basis of the results of gonadotropin-releasing hormone stimulation tests. Girls with CPP underwent a ...
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