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Yanzhong Chen
Guangdong Pharmaceutical University
Controlled releaseChemistryMaterials scienceMontmorilloniteBiochemistry
10Publications
3H-index
39Citations
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Publications 11
Newest
#1Shuo Liu (Guangdong Pharmaceutical University)
#2Xinyue Han (Guangdong Pharmaceutical University)
Last. Qineng Ping (CPU: China Pharmaceutical University)H-Index: 37
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Montmorillonite-loaded solid lipid nanoparticles with good biocompatibility, using Betaxolol hydrochloride as model drug, were prepared by the melt-emulsion sonication and low temperature-solidification methods and drug bioavailability was significantly improved in this paper for the first time to application to the eye. The appropriate physical characteristics were showed, such as the mean particle size, Zeta potential, osmotic pressure, pH values, entrapping efficiency (EE%) and drug content (...
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#1Ting-Ting Yan (Guangdong Pharmaceutical University)
#2Zhufen Lv (Guangdong Pharmaceutical University)H-Index: 3
Last. Yanzhong Chen (Guangdong Pharmaceutical University)H-Index: 3
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AbstractOrodispersible films (ODFs) are promising drug delivery systems for customized medicines as it provide an alternative approach to increase consumer acceptance by advantages of rapid dissolu...
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#1Zijie Zheng (Guangdong Pharmaceutical University)
#2Jieqiong Lv (Guangdong Pharmaceutical University)H-Index: 1
Last. Zhufen Lv (Guangdong Pharmaceutical University)H-Index: 3
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Abstract This study aimed to use three-dimensional printing technology to provide patients with accurate, safe and convenient subdivided drugs and bring the transformation of subdivided drugs’ fabrication in the hospital. The formulation, preparation process, model and printing parameters, relationship between dose and preset model for printing of spironolactone of 2 mg, 4 mg and hydrochlorothiazide of 5 mg subdivided tablets prepared by three-dimensional printers were investigated in the study....
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#1Yawen Zhao (Guangdong Pharmaceutical University)H-Index: 2
#2Juan Li (Guangdong Pharmaceutical University)H-Index: 2
Last. Dongzhi Hou (Guangdong Pharmaceutical University)H-Index: 4
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Abstract Montmorillonite based polymeric nanoparticles was designed to effectively deliver adequate concentrations of drug to the ocular site after topical administration for treatment of glaucoma. In vitro and in vivo studies were carried out to evaluate their drug delivery performances. Betaxolol hydrochloride (BH) intercalated montmorillonite (Mt-BH) was successfully encapsulated into the Eudragit®PO (Mt-BH NPs) via an opportunely emulsification-solvent evaporation technique as indicated by F...
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#1Jiaqi Yan (Guangdong Pharmaceutical University)H-Index: 1
#2Jialin Ren (Guangdong Pharmaceutical University)H-Index: 1
Last. Fan Yang (Guangdong Pharmaceutical University)H-Index: 6
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1 CitationsSource
#1Pan Tian (Guangdong Pharmaceutical University)H-Index: 1
#2Fan Yang (Guangdong Pharmaceutical University)H-Index: 6
Last. Yanzhong Chen (Guangdong Pharmaceutical University)H-Index: 3
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AbstractThe aim of this study was to determine the effect of varying excipient content on the formation and physical properties of 3 D printed tablets. Fifteen different excipient preparations were formed into tablets with radii of 5 mm and thickness of 2 mm, using binder jetting (BJ). The tablets were analyzed by assessing visual and microstructural appearance, friability, hardness, and disintegration time. We found that filling agents with high water solubility (e.g. D-sucrose), binding agents...
1 CitationsSource
#1Pan Tian (Guangdong Pharmaceutical University)H-Index: 1
#2Fan Yang (Guangdong Pharmaceutical University)H-Index: 6
Last. Yanzhong Chen (Guangdong Pharmaceutical University)H-Index: 3
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AbstractIndividualized medicine is a new direction in the field of modern pharmacy. In this study, we assessed the feasibility and accuracy of 3D printing techniques for the preparation of individualized doses of mouth-disintegrating tablets of warfarin. Warfarin sodium, D-sucrose, pregelatinized starch, povidone K30, microcrystalline cellulose, and silicon dioxide (at a ratio of 1:42.45:46.15:5.1:4.9:0.4) were mixed and used as the printing powder in the 3D printer; preset parameters were used....
6 CitationsSource
#1Juan LiH-Index: 2
#2Shuangyan TianH-Index: 3
Last. Dongzhi HouH-Index: 4
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11 CitationsSource
#1Shuangyan TianH-Index: 3
#2Juan LiH-Index: 2
Last. Dongzhi HouH-Index: 4
view all 10 authors...
3 CitationsSource
Canarium pimela K.D. Koenig, Burseraceae, have a long history of use in the Chinese traditional medicine treatment of various ailments including hypertension, and our research team has reported the anti-hypertensive activity and delineated the mechanism involved in the action. The following research aims to evaluate the vasorelaxant and antioxidant activities of ethanol extract from C. pimela leaves and to analyze its chemical composition by ultra-performance liquid chromatography-quadrupole tim...
3 CitationsSource
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