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Yanting Zeng
Guangzhou Medical University
2Publications
1H-index
91Citations
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#1Lichun Tang (Protein Sciences)H-Index: 1
#2Yanting ZengH-Index: 1
Last.Pumin Zhang (Protein Sciences)H-Index: 36
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#1Lichun Tang (Protein Sciences)H-Index: 1
#2Yanting Zeng (Guangzhou Medical University)H-Index: 1
Last.Jianqiao Liu (Guangzhou Medical University)H-Index: 6
view all 11 authors...
Previous works using human tripronuclear zygotes suggested that the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system could be a tool in correcting disease-causing mutations. However, whether this system was applicable in normal human (dual pronuclear, 2PN) zygotes was unclear. Here we demonstrate that CRISPR/Cas9 is also effective as a gene-editing tool in human 2PN zygotes. By injection of Cas9 protein complexed with the appropriate sgRNAs and homology donors into o...
91 CitationsSource
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