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Majid Zeinali
Mashhad University of Medical Sciences
9Publications
3H-index
44Citations
Publications 9
Newest
#1Mohammad Reza Zirak (MUMS: Mashhad University of Medical Sciences)H-Index: 6
#2Soghra Mehri (MUMS: Mashhad University of Medical Sciences)H-Index: 14
Last.Gholamreza Karimi (MUMS: Mashhad University of Medical Sciences)H-Index: 23
view all 6 authors...
Abstract Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The majority of cardiovascular complications are secondary to atherosclerosis. Extensive evidence has showed that environmental pollutants such as cigarette smoke and automobile exhaust increase the risk of developing atherosclerosis. Acrolein, a highly reactive unsaturated aldehyde, is found as a contaminant in air, food and water. Investigations during the last decades have shown that acrolein via various mechani...
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1 CitationsSource
#1Jamshid Tabeshpour (MUMS: Mashhad University of Medical Sciences)H-Index: 6
#2Amirhossein Sahebkar (MUMS: Mashhad University of Medical Sciences)H-Index: 59
Last.Saleh Rakhshani (MUMS: Mashhad University of Medical Sciences)H-Index: 1
view all 7 authors...
6 CitationsSource
#1Majid Zeinali (MUMS: Mashhad University of Medical Sciences)H-Index: 3
#2Naser Tayebi Meybodi (MUMS: Mashhad University of Medical Sciences)H-Index: 1
Last.Hossein Hosseinzadeh (MUMS: Mashhad University of Medical Sciences)H-Index: 49
view all 5 authors...
AbstractChrysin (CH) is a natural flavone which possesses antioxidant, anti-cancer, and anti-inflammatory properties. The aim of the present study was to investigate the effects of CH on biochemical parameters, histopathological changes, and genotoxicity and hematological indices in diazinon (DZN)-induced toxicity in BALB/c mice. We induced sub-acute toxicity in mice using DZN (20 mg/kg/day) and treated them with CH at the 12.5, 25, and 50 mg/kg/day five times/week in 28 days. In our study, DZN ...
1 CitationsSource
#1Majid Zeinali (MUMS: Mashhad University of Medical Sciences)H-Index: 3
Last.Hossein Hosseinzadeh (MUMS: Mashhad University of Medical Sciences)H-Index: 49
view all 3 authors...
Abstract Inflammation and the pro-inflammatory cytokines are associated with numerous chronic diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from natural origin, have a wide range of putative biological activities. Similar to other flavonoids, chrysin (CH) by its anti-oxidative and anti-inflammatory effects is a potential prophylactic agent in immunopathological and physicochemical injuries. This is an overview on putative immunomodulatory activities of flavon...
32 CitationsSource
#1Majid Zeinali (MUMS: Mashhad University of Medical Sciences)H-Index: 3
#2Jamshid Tabeshpour (MUMS: Mashhad University of Medical Sciences)H-Index: 6
Last.Saeid Eslami (MUMS: Mashhad University of Medical Sciences)H-Index: 21
view all 8 authors...
Objective: Inappropriate nonsteroidal anti-inflammatory drugs (NSAIDs) therapy is a common cause of actual and potential adverse effects, such as bleeding and gastrointestinal ulceration, which exacerbates the patient's medical condition and might even be life threatening. We aimed to evaluate and analyze the prescription pattern of NSAIDs in Northeastern Iranian population and also provide suggestions for a more rational prescription behavior for such drugs. Methods: In this cross-sectional ret...
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#1Kamal Razavi-Azarkhiavi (MUMS: Mashhad University of Medical Sciences)H-Index: 6
#2Amir Hosein Jafarian (MUMS: Mashhad University of Medical Sciences)H-Index: 3
Last.Gholamreza Karimi (MUMS: Mashhad University of Medical Sciences)H-Index: 23
view all 8 authors...
Background: Over the past several years, the considerable attention has been progressively given to liposomal formulations of anthracyclines. SinaDoxosome® (Exir Nano Sina Company, Iran) is a pegylated liposomal doxorubicin (DOX) which approved by Food and Drug Administration of IRAN for treatment of some types of cancer. The aim of this study was to compare the biodistribution, efficacy, cardiotoxicity and hepatotoxicity of SinaDoxosome® with Caelyx® in mice bearing C-26 colon carcinoma. Method...
3 CitationsSource
#1Parisa Mirhosseini Moosavi (FUM: Ferdowsi University of Mashhad)H-Index: 1
#2Ali Reza Astaraei (FUM: Ferdowsi University of Mashhad)H-Index: 5
Last.Gholamreza KarimiH-Index: 23
view all 7 authors...
Abstract Iron overload in the amount of 10–20 mg/kg of body weight can induce toxicity. Iron causes its toxic effects in a form of oxidative stress and inhibition of key metabolic enzymes. It seems that montmorillonite clay can reduce absorption of elemental iron by iron fixation in the gastrointestinal tract. The potential effect of montmorillonite in decontaminating the gastrointestinal tract was investigated based on serum iron concentration. In the present experiment, ferrous sulfate (100 mg...
1 CitationsSource
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