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Yue Liu
Capital Medical University
Conventional PCIBiochemistryDiabetes mellitusMedicinePharmacology
9Publications
4H-index
50Citations
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Publications 10
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#2Yanfei Liu (Beijing University of Chinese Medicine)H-Index: 4
Last. Yue LiuH-Index: 4
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#1Jinfan Tian (Capital Medical University)H-Index: 4
#2Mohammad Sharif Popal (Capital Medical University)H-Index: 1
Last. Yue LiuH-Index: 4
view all 7 authors...
Background. There is a crosstalk between endoplasmic reticulum stress (ERS) and autophagy, and autophagy could attenuate endoplasmic reticulum stress-mediated apoptosis. Ginkgo biloba leaf extract (GBE) exerts vascular protection functions. The purpose of the present study is to investigate the role of autophagy in diabetic atherosclerosis (AS) and the effect of GBE on autophagy and ERS. Methods. Network pharmacology was utilized to predict the targets and pathways of the active chemical compoun...
1 CitationsSource
#1Jinfan Tian (Capital Medical University)H-Index: 4
#2Yanfei Liu (Beijing University of Chinese Medicine)H-Index: 4
Last. Shuzheng Lyu (Capital Medical University)H-Index: 4
view all 5 authors...
Diabetes was induced in high-fat diet-fed ApoE−/− mice via administration of low-dose streptozotocin (STZ) for five days. Mice were then treated with GBE (200 or 400 mg/kg) by gastric gavage daily for 12 weeks. Mice in the untreated diabetic group received saline instead, and nondiabetic C57BL/6J mice served as controls. Collagen І and ІІІ mRNA expression was measured by real-time PCR. TNF-α, IL-1β mRNA levels, and NF-κB expression were determined to analyze intramyocardial inflammation. Hallmar...
4 CitationsSource
#1Jinfan Tian (Capital Medical University)H-Index: 4
#2Yue LiuH-Index: 4
Last. Shuzheng Lyu (Capital Medical University)H-Index: 4
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Objective. The aim of the present study was to investigate the predictive value of neutrophil count for no-reflow in patients with ST-segment elevation myocardial infarction (STEMI) who underwent successful primary percutaneous intervention (PCI). Methods. We conducted a retrospective study of 361 patients diagnosed with acute STEMI between 2011 and 2015. All patients underwent successful PCI within 12 h from the onset of symptoms. Angiographic no-reflow was diagnosed based on a post-PCI thrombo...
1 CitationsSource
#1Jinfan TianH-Index: 4
#2Yue LiuH-Index: 4
Last. Keji ChenH-Index: 2
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Background Leaves of Ginkgo biloba, a “living fossil,” have been used as traditional herbal medicine for hundreds of years in China. Currently, its application in vascular protection is gaining much attention. Methods In this manuscript, preclinical studies were reviewed to discuss various mechanisms underlying the vascular protection by Ginkgo biloba extract (GBE). Additionally, we reviewed clinical studies to present the application of GBE in the ischaemic disease. Results GBE, a commonly used...
9 CitationsSource
#1Jinfan TianH-Index: 4
#2Yanfei LiuH-Index: 4
Last. Shuzheng LyuH-Index: 4
view all 5 authors...
An increasing number of patients diagnosed with diabetes mellitus eventually develop severe coronary atherosclerosis disease. Both type 1 and type 2 diabetes mellitus increase the risk of cardiovascular disease associated with atherosclerosis. The cellular and molecular mechanisms affecting the incidence of diabetic atherosclerosis are still unclear, as are appropriate strategies for the prevention and treatment of diabetic atherosclerosis. In this review, we discuss progress in the study of her...
5 CitationsSource
Diabetic cardiomyopathy is one of the major complications among patients with diabetes mellitus. Diabetic cardiomyopathy (DCM) is featured by left ventricular hypertrophy, myocardial fibrosis, and damaged left ventricular systolic and diastolic functions. The pathophysiological mechanisms include metabolic-altered substrate metabolism, dysfunction of microvascular, renin-angiotensin-aldosterone system (RAAS) activation, oxidative stress, cardiomyocyte apoptosis, mitochondrial dysfunction, and im...
9 CitationsSource
#1Jinfan TianH-Index: 4
#2Yue LiuH-Index: 4
Last. Shuzheng LyuH-Index: 4
view all 7 authors...
Background. Insufficient data are available on the potential benefit of selective aspiration and clinical predictors for no-reflow in STEMI patients undergoing primary percutaneous coronary intervention (PPCI) adjunct with aspiration thrombectomy. Objective. The aim of our study was to investigate clinical predictors for insufficient reperfusion in patients with high thrombus burden treated with PPCI and manual aspiration thrombectomy. Methods. From January 2011 till December 2015, 277 STEMI pat...
2 CitationsSource
#1Hua Chen (Capital Medical University)H-Index: 1
#2Lijie Zhang (Capital Medical University)H-Index: 1
Last. Shuzheng Lv (Capital Medical University)H-Index: 13
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Abstract Endothelial dysfunction has been considered as one of potential mechanisms by which depression and stress might contribute to the development of coronary artery disease (CAD). Recent studies suggest that circulating endothelial progenitor cells (EPCs) and brachial artery flow-mediated dilation (FMD) are related to endothelial function and progression of CAD. We investigated the relationships between the level of circulating CD34/KDR + EPCs and CD133/KDR + EPCs, brachial FMD, and scores ...
19 CitationsSource
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