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Le Ba Vinh
Vietnam Academy of Science and Technology
11Publications
2H-index
11Citations
Publications 11
Newest
#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Nguyen Thi Minh Nguyet (CNU: Chungnam National University)H-Index: 2
Last.Young Ho Kim (CNU: Chungnam National University)H-Index: 61
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AbstractUsing various chromatographic techniques, a total of 15 compounds, including one novel megastigmane named tiliaceic acid A (1) and 14 known compounds, were isolated from the traditional med...
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Marine invertebrates and their associated microorganisms are rich sources of bioactive compounds. Among them, coral and its associated microorganisms are promising providers of marine bioactive compounds. The present review provides an overview of bioactive compounds that are produced by corals and coral-associated microorganisms, covering the literature from 2010 to March 2019. Accordingly, 245 natural products that possess a wide range of potent bioactivities, such as anti-inflammatory, cytoto...
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#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Hyun-Jae Jang (Korea Research Institute of Bioscience and Biotechnology)H-Index: 5
Last.Seo Young Yang (CNU: Chungnam National University)H-Index: 12
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Abstract Chromatography of the ethanol extract of the medicinal fruit Stauntonia hexaphylla resulted in the purification of 26 compounds ( 1 − 26 ), including two undescribed triterpene saponins 1 and 2 (hexaphylosides A and B). Their structures were confirmed by spectroscopic data, including IR, HR QTOF MS, 1 H, 13 C-NMR, COSY, HMQC, HMBC, and TOCSY, and HPLC sugar analysis after acid hydrolysis. The anti-inflammatory effects of the high-purity constituents ( 1 – 26 ) on lipopolysaccharide (LPS...
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#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Se Jin Jo (Chonnam National University)
Last.Seo Young Yang (CNU: Chungnam National University)H-Index: 12
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AbstractStauntonia hexaphylla (Lardizabalaceae) is an important medicinal plant in Korea, Japan, and China. Its leaves are used to treat many diseases because of their analgesic, sedative, and diur...
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#1Nguyen Van Thanh (VAST: Vietnam Academy of Science and Technology)H-Index: 8
#2Hyun-Jae Jang (Korea Research Institute of Bioscience and Biotechnology)H-Index: 5
Last.Seo Young Yang (CNU: Chungnam National University)H-Index: 12
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Abstract In a search for anti-inflammatory activity in resources from Vietnamese mangroves, we found that a methanolic extract from the leaves of Calophyllum inophyllum (CIL) showed significant anti-inflammatory effects in vitro. Using various chromatographic techniques, we subsequently isolated 12 compounds (1–12) from a methanolic extract of CIL, including two novel compounds (1–2). The inhibitory effects of these compounds on lipopolysaccharide-induced nitric oxide (NO) production in RAW264.7...
2 CitationsSource
#1Hoang Le Tuan Anh (VAST: Vietnam Academy of Science and Technology)H-Index: 8
#2Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
Last.Young Ho Kim (CNU: Chungnam National University)H-Index: 61
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AbstractUsing various chromatographic separations, four compounds, including one new steroid saponin named vernoamyoside E (1), were isolated from the leaves of the Vietnamese medicinal plant Verno...
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#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Hyun-Jae Jang (Korea Research Institute of Bioscience and Biotechnology)H-Index: 5
Last.Seo Young Yang (CNU: Chungnam National University)H-Index: 12
view all 8 authors...
Abstract Using various chromatographic techniques, 23 triterpene saponins ( 1–23 ) were isolated from an ethanol extract of Stauntonia hexaphylla , including two new compounds ( 12 and 15 ). Their chemical structures were established by comprehensive spectroscopic methods such as 1D- and 2D-NMR, and HR-ESI-MS, and chemical reactions. The anti-inflammatory activities of the isolated saponins were determined using the nitric oxide (NO) assay. Compound 13 exhibited the greatest inhibitory effect (I...
1 CitationsSource
#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Jung Up Park (Chonnam National University)H-Index: 3
Last.Young Ho Kim (CNU: Chungnam National University)H-Index: 61
view all 7 authors...
Korean red ginseng is a traditional health food frequently used to prevent or treat various diseases worldwide. In this study, we evaluated the immunomodulatory activities of eleven compounds (1–11) isolated from Korean red ginseng, focusing on T cell function. First, the effects of the eleven compounds were studied on the regulation of IL-2, a potent T cell growth factor. Compounds 5, 7, and 9 significantly increased IL-2 secretion in phorbol 12-myristate 13-acetate (PMA)/ionomycin (Io)-induced...
2 CitationsSource
#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2KimJi-YoungH-Index: 141
Last.Young Ho Kim (CNU: Chungnam National University)H-Index: 61
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The goal of this study was to identify soluble epoxide hydrolase (sEH) inhibitors from plants. Our efforts led to the isolation of nine phenolic glycosides 1–9 from the roots of Polygala tenuifolia Willd. The structures of compounds were determined by spectroscopic methods, including mass spectroscopy and one-dimensional and two-dimensional nuclear magnetic resonance, and compared with published data. All the isolated compounds were evaluated for their inhibitory activity against sEH. The IC50 v...
1 CitationsSource
#1Le Ba Vinh (VAST: Vietnam Academy of Science and Technology)H-Index: 2
#2Yunjeong Lee (CNU: Chungnam National University)H-Index: 1
Last.Young Ho Kim (CNU: Chungnam National University)H-Index: 61
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Abstract Panax ginseng has been the subject of extensive research on potential medicinal materials. The goal of this study was search the chemical constituents and biological activities of processed Panax ginseng , Korean red ginseng. Our efforts led to the isolation eleven compounds ( 1 – 11 ) including two new compounds 1 and 2 from Korean red ginseng using various chromatographic techniques. Chemical structures of isolated compounds were demonstrated by spectroscopic methods (1D-, 2D-NMR, and...
5 CitationsSource
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