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Giuseppe Pugliese
Sapienza University of Rome
216Publications
45H-index
5,379Citations
Publications 216
Newest
Published on Apr 25, 2019in BMC Medicine8.29
Anna Solini37
Estimated H-index: 37
(UniPi: University of Pisa),
Giuseppe Penno33
Estimated H-index: 33
(UniPi: University of Pisa)
+ 9 AuthorsMarco Giorgio Baroni28
Estimated H-index: 28
(University of Cagliari)
Resistant hypertension is independently associated with an increased risk of death in the general hypertensive population. We assessed whether resistant hypertension is an independent predictor of all-cause mortality in individuals with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study. On 31 October 2015, vital status information was retrieved for 15,656 of the 15,773 participants enrolled in 2006–2008. Based on baseline blood pressure (BP)...
Published on Jul 11, 2019in Current Medicinal Chemistry3.89
Stefano Menini32
Estimated H-index: 32
(Sapienza University of Rome),
Carla Iacobini25
Estimated H-index: 25
(Sapienza University of Rome)
+ 1 AuthorsGiuseppe Pugliese45
Estimated H-index: 45
(Sapienza University of Rome)
Published on Jul 1, 2019in The American Journal of Medicine4.76
Jonida Haxhi6
Estimated H-index: 6
(Sapienza University of Rome),
Stefano Balducci17
Estimated H-index: 17
(Sapienza University of Rome),
Giuseppe Pugliese45
Estimated H-index: 45
(Sapienza University of Rome)
Published on May 1, 2019in The Lancet59.10
Hiddo J. Lambers Heerspink44
Estimated H-index: 44
(UMCG: University Medical Center Groningen),
H Parving99
Estimated H-index: 99
(UCPH: University of Copenhagen)
+ 704 AuthorsHirofumi Makino69
Estimated H-index: 69
(Okayama University)
Summary Background Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing significant sodium retention. We report the long-term effects of treatment with atrasentan on major renal outcomes. Methods We did this double-blind, randomised, placebo-controlled trial at 689 sites in 41 countries. We enrolled adults aged 18–85 years with type 2 diabetes, estimated glomerular filtration rate (e...
Published on May 1, 2019in Journal of Hepatology18.95
Valeria Grancini5
Estimated H-index: 5
(University of Milan),
Maddalena Trombetta15
Estimated H-index: 15
+ 8 AuthorsRiccardo C. Bonadonna53
Estimated H-index: 53
(University of Parma)
Background & Aims Diabetes occurring as a direct consequence of loss of liver function is usually characterized by non-diabetic fasting plasma glucose (FPG) and haemoglobin A 1c (HbA 1c ) levels and should regress after orthotopic liver transplantation (OLT). This observational, longitudinal study investigated the relationship between the time-courses of changes in all 3 direct determinants of glucose regulation, i.e. , β-cell function, insulin clearance and insulin sensitivity, and diabetes reg...
Published on Mar 5, 2019in JAMA51.27
Stefano Balducci17
Estimated H-index: 17
(Sapienza University of Rome),
Valeria D’Errico4
Estimated H-index: 4
(Sapienza University of Rome)
+ 10 AuthorsSilvano Zanuso2
Estimated H-index: 2
(University of Greenwich)
Importance There is no definitive evidence that changes in physical activity/sedentary behavior can be maintained long term in individuals with type 2 diabetes. Objective To investigate whether a behavioral intervention strategy can produce a sustained increase in physical activity and reduction in sedentary time among individuals with type 2 diabetes. Design, Setting, and Participants The Italian Diabetes and Exercise Study 2 was an open-label, assessor-blinded, randomized clinical superiority ...
Published on Mar 1, 2019in Pharmacological Research5.57
Valeria Grancini5
Estimated H-index: 5
(University of Milan),
Veronica Resi5
Estimated H-index: 5
(University of Milan)
+ 2 AuthorsEmanuela Orsi18
Estimated H-index: 18
(University of Milan)
Abstract Diabetes is a common feature in cirrhotic individuals both before and after liver transplantation and negatively affects prognosis. Certain aetiological agents of chronic liver disease and loss of liver function per se favour the occurrence of pre-transplant diabetes in susceptible individuals, whereas immunosuppressant treatment, changes in lifestyle habits, and donor- and procedure-related factors contribute to diabetes development/persistence after transplantation. Challenges in the ...
Published on Mar 1, 2019in Metabolism-clinical and Experimental6.51
Carla Iacobini25
Estimated H-index: 25
(Sapienza University of Rome),
Giuseppe Pugliese45
Estimated H-index: 45
(Sapienza University of Rome)
+ 2 AuthorsStefano Menini32
Estimated H-index: 32
(Sapienza University of Rome)
Abstract Obesity-related disease complications reduce life quality and expectancy and increase health-care costs. Some studies have suggested that obesity not always entails metabolic abnormalities and increased risk of cardiometabolic complications. Because of the lack of universally accepted criteria to identify metabolically healthy obesity (MHO), its prevalence varies widely among studies. Moreover, the prognostic value of MHO is hotly debated, mainly because it likely shifts gradually towar...
Published on Dec 1, 2018in Journal of The American Society of Nephrology8.55
Valeria Saglimbene14
Estimated H-index: 14
,
Suetonia C. Palmer38
Estimated H-index: 38
(University of Otago)
+ 22 AuthorsFabio Pellegrini50
Estimated H-index: 50
(Biogen Idec)
Background The comparative effectiveness of treatment with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or their combination in people with albuminuria and cardiovascular risk factors is unclear. Methods In a multicenter, randomized, open label, blinded end point trial, we evaluated the effectiveness on cardiovascular events of ACE or ARB monotherapy or combination therapy, targeting BP Results Because of slow enrollment, the trial was modified and stoppe...
Published on Nov 1, 2018in Diabetologia7.11
Giuseppe Penno33
Estimated H-index: 33
(UniPi: University of Pisa),
Anna Solini37
Estimated H-index: 37
(UniPi: University of Pisa)
+ 9 AuthorsMarco Scardapane6
Estimated H-index: 6
Aims/hypothesis Non-albuminuric renal impairment has become the prevailing diabetic kidney disease (DKD) phenotype in individuals with type 2 diabetes and an estimated GFR (eGFR) <60 ml min−1 1.73 m−2. In the present study, we compared the rate and determinants of all-cause death in individuals with this phenotype with those in individuals with albuminuric phenotypes.
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