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Xiao Yang
Sichuan University
PsychiatryPsychologyFunctional magnetic resonance imagingMajor depressive disorderMedicine
21Publications
7H-index
108Citations
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Publications 26
Newest
#1Shile Qi (Georgia Institute of Technology)H-Index: 5
#2Juan R. Bustillo (UNM: University of New Mexico)H-Index: 44
Last. Xiao Yang (Sichuan University)H-Index: 7
view all 15 authors...
Schizophrenia (SZ) is frequently concurrent with substance use, depressive symptoms, social communication and attention deficits. However, the relationship between common brain networks (e.g., SZ vs. substance use, SZ vs. depression, SZ vs. developmental disorders) with SZ on specific symptoms and cognition is unclear. Symptom scores were used as a reference to guide fMRI-sMRI fusion for SZ (n = 94), substance use with drinking (n = 313), smoking (n = 104), major depressive disorder (MDD, n = 26...
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#1Jianlong Zhao (CAS: Chinese Academy of Sciences)H-Index: 21
#2Jinjie Huang (Harbin University of Science and Technology)
Last. Vince D. Calhoun (Georgia Institute of Technology)H-Index: 93
view all 11 authors...
Abstract As a popular deep learning method, generative adversarial networks (GAN) have achieved outstanding performance in multiple classifications and segmentation tasks. However, the application of GANs to fMRI data is relatively rare. In this work, we proposed a functional network connectivity (FNC) based GAN for classifying psychotic disorders from healthy controls (HCs), in which FNC matrices were calculated by correlation of time courses derived from non-artefactual fMRI independent compon...
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#1Li Yao (Sichuan University)H-Index: 10
#2Fei Li (Sichuan University)H-Index: 11
Last. Xiao Yang (Sichuan University)H-Index: 7
view all 18 authors...
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#1Shile Qi (Georgia Institute of Technology)H-Index: 5
#2Christopher C. Abbott (UNM: University of New Mexico)H-Index: 13
Last. Vince D. Calhoun (Georgia Institute of Technology)H-Index: 93
view all 13 authors...
Electroconvulsive therapy is regarded as the most effective antidepressant treatment for severe and treatment-resistant depressive episodes. Despite the efficacy of electroconvulsive therapy, the neurobiological underpinnings and mechanisms underlying electroconvulsive therapy induced antidepressant effects remain unclear. The objective of this investigation was to identify electroconvulsive therapy treatment responsive multimodal biomarkers with the 17-item Hamilton Depression Rating Scale guid...
1 CitationsSource
#1Xiongwei Qi (Sichuan University)H-Index: 1
#2Huanhuan Fan (Sichuan University)H-Index: 2
Last. Xiaohong Ma (Sichuan University)H-Index: 23
view all 10 authors...
Visual deficits have been reported in abundance by recent studies on major depressive disorder. Pattern glare manifests as visual distortions, such as the symptoms of headache, glare, eyestrain, illusions of shapes, colors, and motion when viewing repetitive striped patterns, of which some can be observed in major depressive disorder. Inspired by what mentioned, the present study aims to explore whether there exists association between pattern glare and major depressive disorder and further atte...
2 CitationsSource
#1Yayun ChenH-Index: 1
#2Xiao YangH-Index: 7
Last. Xiaohong MaH-Index: 23
view all 13 authors...
Background: Research on antipsychotics and early mortality in schizophrenia has arisen from Western countries and results show that mortality from natural causes is obviously increased in schizophrenia. China, differs largely from Western countries in health and social welfare systems, and Asian patients are more susceptible to side-effects and might require less antipsychotics than their Western counterparts. We, therefore, investigated the association between antipsychotic use and increased mo...
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#1Yu Wang (Sichuan University)H-Index: 2
#2Xiao Yang (Sichuan University)H-Index: 7
Last. Xiaohong Ma (Sichuan University)H-Index: 23
view all 14 authors...
Abstract We conducted a 24-week, randomized, double-blind parallel-controlled trial to test whether buspirone is beneficial to improve cognitive deficits of schizophrenia because it remains unclear. Two hundred patients received in random order either co-treatment buspirone with AAPDs or monotherapy with AAPDs. All patients had been treated with a stable dosage of AAPDs for at least three months. The positive and negative syndrome scale (PANSS), Hamilton Depression Scale-24 (HAMD-24), and 14-ite...
1 CitationsSource
Purpose: Major depression disorder (MDD) was associated with inflammatory processes, but association results of inflammatory syndrome and MDD were inconsistent. To provide more evidence, we measured the plasma levels of IL-1β, IL-6, interferon (INT)-α2, INT-γ, and tumor necrosis factor (TNF)-α in patients having MDD and explored correlations between the five proinflammatory cytokines and specific depressive symptoms. Patients and methods: Plasma concentrations of IL-1β, IL-6, INT-α2, INT-γ, and ...
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#1Li Yao (Sichuan University)H-Index: 10
#2Fei Li (Sichuan University)H-Index: 11
Last. Tao Li (Sichuan University)H-Index: 46
view all 18 authors...
This study compared the topological organization of brain function in never-treated and treated long-term schizophrenia patients. In a cross-sectional study, 21 never-treated schizophrenia patients with illness duration over 5 years, 26 illness duration-matched antipsychotic-treated patients and 24 demographically-matched healthy controls underwent a resting-state functional magnetic resonance imaging (MRI) scan. The topological properties of brain functional networks were compared across groups...
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#1Sugai Liang (Sichuan University)H-Index: 4
#2Qiang Wang (Sichuan University)H-Index: 27
Last. Tao Li (Sichuan University)H-Index: 46
view all 14 authors...
Identifying data-driven biotypes of major depressive disorder (MDD) has promise for the clarification of diagnostic heterogeneity. However, few studies have focused on white-matter abnormalities for MDD subtyping. This study included 116 patients with MDD and 118 demographically-matched healthy controls assessed by diffusion tensor imaging and neurocognitive evaluation. Hierarchical clustering was applied to the major fiber tracts, in conjunction with tract-based spatial statistics, to reveal wh...
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