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Rosalinda Posadas-Sánchez
National Autonomous University of Mexico
EndocrinologyCoronary artery diseasePopulationDiabetes mellitusMedicine
109Publications
15H-index
707Citations
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Publications 112
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Last. José Manuel FragosoH-Index: 3
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Recent studies have shown that P-selectin promotes the early formation of atherosclerotic plaque. The aim of the present study was to evaluate whether the SELP gene single nucleotide polymorphisms (SNPs) are associated with presence of acute coronary syndrome (ACS) and with plasma P-selectin levels in a case-control association study. The sample size was estimated for a statistical power of 80%. We genotyped three SELP (SELP Ser290Asn, SELP Leu599Val, and SELP Thr715Pro) SNPs using 5’ exonucleas...
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Last. Gilberto Vargas-AlarcónH-Index: 33
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Inflammation has been involved in the development of atherosclerosis, type 2 diabetes mellitus, insulin resistance, and obesity. Interleukin 20 is a pro-inflammatory cytokine encoded by a polymorphic gene located in chromosome 1. The aim of the study was to evaluate the association of two IL-20 polymorphisms (rs1400986 and rs1518108) with subclinical atherosclerosis (SA), cardiovascular risk factors and IL-20 levels in a cohort of Mexican individuals. The polymorphisms were determined in 274 ind...
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Last. José Manuel FragosoH-Index: 13
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#1Thelma Beatriz González-Castro (UJAT: Universidad Juárez Autónoma de Tabasco)H-Index: 9
#2Ruben Blachman-Braun (UM: University of Miami)H-Index: 1
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Abstract Nephrolithiasis is a complex disease in which its pathophysiology is strongly influenced by genetics. Polymorphisms of the vitamin D receptor ( VDR ) gene have been reported to be associated with the development of kidney stones which in most cases are composed predominantly of calcium salts. For the purpose of this study, we performed a systematic review and meta-analysis to analyze the association of BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236) and FokI (rs2228570) polymorphism...
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Interleukin-23 (IL-23) has been associated with atherosclerosis in both humans and animal models with contradictory results. This cytokine is conformed by an α p19 (encoded by IL-23A gene) and a β ...
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#1Thelma Beatriz González-Castro (UJAT: Universidad Juárez Autónoma de Tabasco)H-Index: 9
#2Yazmín Hernández-Díaz (UJAT: Universidad Juárez Autónoma de Tabasco)H-Index: 6
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Cardiovascular diseases (CVD) are group of complex and multifactorial pathologies, in which interleukin-6 (IL-6) gene polymorphisms have been associated with several components of the CVD. Thus, in this study, we thoroughly reviewed and meta-analyzed evidence on the association between the IL-6 (rs1800795) gene polymorphism and CVD. We systematically searched in the PubMed, Web of Sciences, and Scopus databases. The analyses were performed using five study groups based on (1) a combined pool of ...
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