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Junqiao Wang
Nanchang University
PolysaccharideChemistryAntioxidantChromatographyBiochemistry
11Publications
5H-index
82Citations
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Publications 15
Newest
#1Wucheng Qi (NCU: Nanchang University)H-Index: 1
#2Xingtao Zhou (NCU: Nanchang University)H-Index: 2
Last. Mingyong Xie (Jiangxi Normal University)H-Index: 44
view all 8 authors...
Abstract Cordyceps sinensis is thought to have anti-cancer effects, but its mechanisms remain elusive. In this study, we aimed to investigate the anti-cancer effect of Cordyceps sinensis polysaccharide (CSP) on human colon cancer cell line (HCT116) and its mechanism. Results indicated that CSP significantly inhibited the proliferation of HCT116 cells, increased autophagy and apoptosis, while blocked autophagy flux and lysosome formation. Further experiments showed that CSP decreased the expressi...
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#1Mengxi Ying (NCU: Nanchang University)H-Index: 1
#2Qiang Yu (NCU: Nanchang University)H-Index: 14
Last. Mingyong Xie (Jiangxi Normal University)H-Index: 44
view all 8 authors...
Abstract The present study aimed to investigate the protective effect of cultured Cordyceps sinensis polysaccharides (CSP) on cyclophosphamide (Cy)-induced intestinal mucosal immunosuppression and microbial dysbiosis in mice. Results showed that CSP stimulated cytokines secretion (IL-12, IFN-γ, IL-4, IL-13, IL-6, IL-17, IL-10, TGF-β3, TNF-α, IL-2, IL-21) and transcription factors production (T-bet, GATA-3, RORγt, Foxp3). TLRs (TLR-2, TLR-4, TLR-6) and NF-κB pathway key proteins (p-IκB-α, NF-κB p...
1 CitationsSource
#1Hui Zhang (USST: University of Shanghai for Science and Technology)H-Index: 2
#1Hui Zhang (USST: University of Shanghai for Science and Technology)H-Index: 6
Last. Lianzhong Ai (USST: University of Shanghai for Science and Technology)H-Index: 9
view all 6 authors...
Abstract A polysaccharide from tamarind seeds (TSP) was characterized in terms of backbone and side chain structural features, as well as conformational property using methylation and GC–MS analysis, 2D NMR, MALDI-TOF MS, and high performance size exclusion chromatography (HPSEC). Results showed that TSP was a galactoxyloglucan (GXG) consisting of glucose, xylose, and galactose in a molar ratio of 3.1: 1.7: 1.0. The Mw was determined to be 524.0 kDa with radius of gyration (Rg) of 55.6 nm. The c...
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#1Junqiao WangH-Index: 5
#1Jun-Qiao WangH-Index: 11
Last. Shaoping NieH-Index: 40
view all 3 authors...
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#1Yi ZhangH-Index: 1
#2Hongxin Wang (Jiangnan University)H-Index: 1
Last. Steve W. Cui (AAFC: Agriculture and Agri-Food Canada)H-Index: 38
view all 5 authors...
Abstract A water-soluble polysaccharide (JCP-40) from Dendrobium nobile Lindl. was extracted and purified. It was demonstrated as a single symmetrical peak based on HPSEC analysis and had an average molecular weight of 67.5 kDa. Combined with monosaccharide composition analysis, methylation analysis, 1D/2D NMR spectroscopy, the structural features of JCP-40 was proposed as follows: the major sugar residues of JCP-40 consisted of →4)-β-ᴅ-Manp-(1→ and →4)-β-ᴅ-Glcp-(1 → . Acetyl groups were found a...
2 CitationsSource
#1Mengxi Ying (NCU: Nanchang University)H-Index: 1
#2Qiang Yu (NCU: Nanchang University)H-Index: 14
Last. Mingyong Xie (NCU: Nanchang University)H-Index: 44
view all 9 authors...
Abstract Intestine is not only the largest digestive and absorbing organ, but also an important defensive barrier of the body. Maintaining healthy intestinal barrier is a prerequisite for intestinal function. In this study, polysaccharides from the cultured Cordyceps sinensis (CSP) were orally given to cyclophosphamide (Cy)-treated mice to investigate its protective effect on intestinal barrier injury. Results showed that CSP had positive effects on intestinal morphology, including restoring vil...
1 CitationsSource
#1Junqiao Wang (NCU: Nanchang University)H-Index: 5
#2Shuping Chen (NCU: Nanchang University)H-Index: 3
Last. Mingyong Xie (NCU: Nanchang University)H-Index: 44
view all 8 authors...
A water-soluble β-D-glucan was obtained from wild Cordyceps sinensis (C. sinensis) by alkali solution and ethanol precipitation. The structure characteristics were determined using high performance anion exchange chromatography coupled with pulsed amperometric detection (HPAEC-PAD), methylation combined with gas chromatography-mass spectrometry (GC-MS), and 1D/2D NMR spectroscopy. Results showed that the β-D-glucan had a structure of every seven (1→3)-β-D-Glcp backbone residues with two (1→6)-β-...
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#1Shuping Chen (NCU: Nanchang University)H-Index: 3
#2Junqiao Wang (NCU: Nanchang University)H-Index: 5
Last. Shaoping Nie (NCU: Nanchang University)H-Index: 40
view all 5 authors...
Abstract Polysaccharide is one of the main bioactive substances in Cordyceps sinensis ( C. sinensis ). The aim of this study was to investigate the effect of polysaccharide from natural C. sinensis (CSP) on intestinal mucosal immunity and antioxidant activity in cyclophosphamide (Cy)-induced intestinal immunosuppressed mice, further to explore the potential mechanism. Results showed that in mice with Cy-induced intestinal injury, the supplement of CSP (25, 50, 100 mg/kg·bw) significantly increas...
2 CitationsSource
#1Jun LuH-Index: 92
#2Keyu Kally ShiH-Index: 1
Last. Shaoping NieH-Index: 40
view all 13 authors...
Fucoidan, the complex fucose-containing sulphated polysaccharide varies considerably in structure, composition, and bioactivity, depending on the source, species, seasonality, and extraction method. In this study, we examined five fucoidans extracted from the same seaweed species Undaria pinnatifida but from different geological locations, and compared them to the laboratory-grade fucoidan from Sigma (S). The five products differed in molecular composition. The amount of over 2 kDa low molecular...
3 CitationsSource
#1Lijiao Kan (NCU: Nanchang University)H-Index: 6
#2Shaoping Nie (NCU: Nanchang University)H-Index: 40
Last. Ke Song (NCU: Nanchang University)H-Index: 1
view all 10 authors...
Abstract Twenty-nine legumes were assessed for their nutritional and phytochemical compositions. Soybean and black soybean had the highest protein contents (34.05–42.65 g/100 g DW, dry weight of legumes), particularly being a rich source of lysine (1.78–2.23 g/100 g DW. Soybean and black soybean had the highest fat contents (14.13–22.19 g/100 g DW). Broad beans had the highest unsaturated fatty acids (83.57–89.01 g/100 g fatty acid), particularly rich in α-linolenic and linoleic acid. The highes...
8 CitationsSource
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