Match!
Manoj Kumar Barthwal
Central Drug Research Institute
100Publications
22H-index
1,595Citations
Publications 99
Newest
#1Priya Gupta (Central Drug Research Institute)H-Index: 1
#2Amit Kumar (Central Drug Research Institute)H-Index: 14
Last.Manoj Kumar Barthwal (Central Drug Research Institute)H-Index: 22
view all 9 authors...
Source
#1Amit KumarH-Index: 27
#2P. C. GuptaH-Index: 2
Last.Manoj Kumar BarthwalH-Index: 22
view all 6 authors...
Source
#1Ankita Singh (Central Drug Research Institute)H-Index: 9
#2Vishal Singh (Central Drug Research Institute)H-Index: 16
Last.Manoj Kumar Barthwal (Central Drug Research Institute)H-Index: 22
view all 7 authors...
Source
#1Samreen Sadaf (Central Drug Research Institute)H-Index: 1
#2Deepika Awasthi (Central Drug Research Institute)H-Index: 7
Last.Madhu Dikshit (Central Drug Research Institute)H-Index: 34
view all 7 authors...
Abstract Previous studies from this lab and others have demonstrated that nitric oxide (NO) in a concentration dependent manner, modulated neutrophil and leukemic cell survival. Subsequent studies delineated importance of iNOS in neutrophil differentiation and leukemic cell death. On the contrary, role of nNOS in survival of these cells remains least understood. Present study was therefore undertaken to assess and compare the role of iNOS and nNOS in the survival of NOS overexpressing myelocytic...
Source
#1Abrar Ali Khan (Indian Institute of Technology Madras)H-Index: 3
#2Heena Agarwal (Central Drug Research Institute)H-Index: 2
Last.Nitish R. Mahapatra (Indian Institute of Technology Madras)H-Index: 22
view all 8 authors...
Hypercholesterolemia is a strong predictor of cardiovascular diseases. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase gene (Hmgcr) coding for the rate-limiting enzyme in the cholesterol biosynthesis pathway is a crucial regulator of plasma cholesterol levels. However, the post-transcriptional regulation of Hmgcr remains poorly understood. The main objective of this study was to explore the role of miRNAs in the regulation of Hmgcr expression. Systematic in silico predictions and experimental an...
Source
Source
#1S. Santosh Reddy (CSIR: Council of Scientific and Industrial Research)
#2Heena Agarwal (CSIR: Council of Scientific and Industrial Research)
Last.Manoj Kumar Barthwal (CSIR: Council of Scientific and Industrial Research)H-Index: 22
view all 4 authors...
Source
#1Samreen Sadaf (Central Drug Research Institute)H-Index: 1
#2Abhishek Singh (Central Drug Research Institute)H-Index: 11
Last.Madhu Dikshit (Central Drug Research Institute)H-Index: 34
view all 10 authors...
1 CitationsSource
#1Anant Jaiswal (CSIR: Council of Scientific and Industrial Research)H-Index: 1
#2Sukka Santosh Reddy (AcSIR: Academy of Scientific and Innovative Research)H-Index: 1
Last.Manoj Kumar Barthwal (CSIR: Council of Scientific and Industrial Research)H-Index: 22
view all 5 authors...
In human adipose tissue and obesity, miR-99a expression is negatively correlated with inflammation. Therefore, the present study investigated the role of miR-99a in macrophage phenotype activation and adipose tissue inflammation. M2 BMDMs showed a significant increase in miR-99a expression when compared to the M0 and M1 phenotypes. Phenotype-switching experiments established an association between upregulated miR-99a expression and the M2 phenotype. Overexpression of miR-99a prevented M1 phenoty...
2 CitationsSource
#1Abrar Ali Khan (Indian Institute of Technology Madras)H-Index: 3
#2Poovitha Sundar (Indian Institute of Technology Madras)
Last.Nitish R. Mahapatra (Indian Institute of Technology Madras)H-Index: 22
view all 8 authors...
3-Hydroxy-3-methyl glutaryl-coenzyme A reductase (Hmgcr) encoding the rate-limiting enzyme in the cholesterol biosynthesis pathway is a candidate gene for essential hypertension (EH). However, the regulation of Hmgcr in rat models of hypertension (viz. Spontaneously Hypertensive Rats [SHR] and its normotensive control Wistar/Kyoto [WKY] strain) is unknown. Here, we show that Hmgcr transcript and protein levels are diminished in liver tissues of SHR as compared to WKY. Consistently, a number of o...
Source
12345678910