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Amy Warner
AstraZeneca
1Publications
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#1Amy Warner (AstraZeneca)H-Index: 1
#2Ann Kjellstedt (AstraZeneca)H-Index: 9
Last.Daniel Lindén (AstraZeneca)H-Index: 19
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Activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT) present potential new therapies for obesity and type 2 diabetes. Here, we examined the effects of β3-adrenergic stimulation on tissue-specific uptake and storage of free fatty acids (FFA) and its implications for whole-body FFA metabolism in diet-induced obese rats using a multi-radiotracer technique. Male Wistar rats were high fat-fed for 12 weeks and administered β3-agonist CL316,243 (CL, 1 mg/kg/day) or saline...
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