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John Day
University of California, Riverside
23Publications
13H-index
818Citations
Publications 23
Newest
Published on Apr 13, 2010in Biochemistry 3.00
Steven B. Larson19
Estimated H-index: 19
,
John Day13
Estimated H-index: 13
,
Alexander McPherson54
Estimated H-index: 54
(University of California, Irvine)
Further refinement of the model using maximum likelihood procedures and re-evaluation of the native electron density map has shown that crystals of pig pancreatic α-amylase, whose structure we reported more than fifteen years ago, in fact contain a substantial amount of carbohydrate. The carbohydrate fragments are the products of glycogen digestion carried out as an essential step of the protein's purification procedure. In particular, the substrate-binding cleft contains a limit dextrin of six ...
25 Citations Source Cite
Published on Jan 1, 1998in Journal of Molecular Biology 4.89
Steven B. Larson7
Estimated H-index: 7
(University of California, Riverside),
John Day13
Estimated H-index: 13
(University of California, Riverside)
+ 1 AuthorsAlexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
Published on Aug 1, 1998
Joseph D. Ng3
Estimated H-index: 3
,
Bernard Lorber27
Estimated H-index: 27
+ 4 AuthorsAlexander McPherson2
Estimated H-index: 2
Published on Mar 1, 1998in Journal of Molecular Biology 4.89
Steven B. Larson7
Estimated H-index: 7
(University of California, Riverside),
John Day13
Estimated H-index: 13
(University of California, Riverside)
+ 1 AuthorsAlexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
Abstract The molecular structure of satellite tobacco mosaic virus (STMV) has been refined to 1.8 A resolution using X-ray diffraction data collected from crystals grown in microgravity. The final R value was 0.179 and R free was 0.184 for 219,086 independent reflections. The final model of the asymmetric unit contained amino acid residues 13 to 159 of a coat protein monomer, 21 nucleotides, a sulfate ion, and 168 water molecules. The nucleotides were visualized as 30 helical segments of nine ba...
96 Citations Source Cite
Published on Feb 1, 1997in Structure 4.91
Joseph D. Schrag29
Estimated H-index: 29
,
Yunge Li17
Estimated H-index: 17
+ 12 AuthorsJoel D. Oliver2
Estimated H-index: 2
(Procter & Gamble)
Abstract Background: The interfacial activation of lipases results primarily from conformational changes in the enzymes which expose the active site and provide a hydrophobic surface for interaction with the lipid substrate. Comparison of the crystallization conditions used and the structures observed for a variety of lipases suggests that the enzyme conformation is dependent on solution conditions. Pseudomonas cepacia lipase (PCL) was crystallized in conditions from which the open, active confo...
200 Citations Source Cite
Published on Feb 1, 1996in Journal of Molecular Biology 4.89
Nenad Ban6
Estimated H-index: 6
(University of California, Riverside),
John Day13
Estimated H-index: 13
(University of California, Riverside)
+ 2 AuthorsAlexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
Abstract The structure of the Fab fragment of the mouse anti-anti-idiotypic monoclonal antibody (mAb) GH1002 was solved by X-ray crystallography. mAb GH1002 was elicited with the syngeneic anti-idiotype mAb MK2-23 which mimics the determinant defined by anti-human high molecular weight-melanoma associated antigen (HMW-MAA) mAb 763.74. The Fab fragments of mAb GH1002 exist in the crystal as dimers related by crystallographic 2-fold axes. The interface between dyad-related Fab fragments is formed ...
13 Citations Source Cite
Published on Jan 1, 1995in The FASEB Journal 5.59
Nenad Ban6
Estimated H-index: 6
(University of California, Riverside),
Carlos Escobar2
Estimated H-index: 2
(University of California, Riverside)
+ 3 AuthorsAlexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
The crystal structure of anti-idiotopic Fab 409.5.3, made against an E2 specific feline infectious peritonitis virus-neutralizing antibody 730.1.4, has been determined in its free from, at 2.9 A resolution by molecular replacement. This antibody, used as an immmunogen, elicits the production of anti-anti-idiotypic antibodies that in turn neutralize the virus. The structure of the uncomplexed Fab was refined using constrained-restrained least squares minimization and simulated annealing in combin...
21 Citations Source Cite
Published on Jul 1, 1995in Biophysical Journal 3.50
Stanley Koszelak11
Estimated H-index: 11
(University of California, Riverside),
John Day13
Estimated H-index: 13
(University of California, Riverside)
+ 2 AuthorsAlexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
Two T = 1 and one T = 3 plant viruses, along with a protein, were crystallized in microgravity during the International Microgravity Laboratory-2 (IML-2) mission in July of 1994. The method used was liquid-liquid diffusion in the European Space Agency's Advanced Protein Crystallization Facility (APCF). Distinctive alterations in the habits of Turnip Yellow Mosaic Virus (TYMV) crystals and hexagonal canavalin crystals were observed. Crystals of cubic Satellite Tobacco Mosaic Virus (STMV) more tha...
48 Citations Source Cite
Published on Jan 1, 1995in Proteins
Mary A. Canady1
Estimated H-index: 1
(University of California, Riverside),
John Day13
Estimated H-index: 13
(University of California, Riverside),
Alexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
Turnip yellow mosaic virus (TYMV) was purified from Chinese cabbage and crystallized in a form that permits high resolution structural analysis using X-ray diffraction. The crystals have a hexagonal bipyramidal morphology and often achieve dimensions of 1.0 × 1.0 × 0.5 mm. The crystals appear to be of hexagonal space group P6222 with a = b = 525 A, c=315 A, but we cannot strictly rule out the possibility that the space group is P622. They appear different than any crystals of TYMV previously rep...
14 Citations Source Cite
Published on Mar 1, 1995in Proteins
Mary A. Canady1
Estimated H-index: 1
(University of California, Riverside),
Catherine A. Leja4
Estimated H-index: 4
(University of California, Riverside)
+ 1 AuthorsAlexander McPherson54
Estimated H-index: 54
(University of California, Riverside)
Tomato aspermy virus (TAV) is a member of the T = 3 cucumovirus group, and the chrysanthemum strain (C-TAV) has been crystallized in a form suitable for X-ray structural analysis. The crystals, which grow in 14–17% ethanol at pH 8.5, are of orthorhombic space group I222 with unit cell dimensions of a = 295.1 A, b = 320.5 A, and c = 383.6 A. There are two T = 3 virus particles in the unit cell, which means that they must be centered at 0,0,0 and 1/2, 1/2, 1/2 with icosahedral 222 symmetry element...
1 Citations Source Cite
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