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Xue Li
Xinxiang Medical University
21Publications
8H-index
173Citations
Publications 21
Newest
#1Peige Song (Xinxiang Medical University)H-Index: 6
#2Xue Li (Xinxiang Medical University)H-Index: 8
Last.Zengli Yu (Xinxiang Medical University)H-Index: 2
view all 7 authors...
Normal weight central obesity (NWCO), a distinct phenotype of obesity that is associated with a higher risk of cardiometabolic dysregulation, has received growing attention in the scientific literature. In this study, we aimed to report the prevalence of NWCO in the general Chinese adults and its secular trend from 1993 to 2011. The comorbid cardiometabolic risk of NWCO was also explored. Data from the China Health and Nutrition Survey (CHNS) 1993–2011 were obtained. NWCO was defined as the comb...
1 CitationsSource
#1Tian Yang (Edin.: University of Edinburgh)H-Index: 1
#2Xue Li (Edin.: University of Edinburgh)H-Index: 8
Last.Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 7
view all 10 authors...
1 CitationsSource
#1Yazhou He (Edin.: University of Edinburgh)H-Index: 3
#2Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 7
Last.Maria Timofeeva (Edin.: University of Edinburgh)H-Index: 10
view all 10 authors...
Source
#1Xue Li (Edin.: University of Edinburgh)H-Index: 8
#2Xiangrui Meng (Edin.: University of Edinburgh)H-Index: 5
Last.Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 40
view all 15 authors...
Background The role of urate in cardiovascular diseases (CVDs) has been extensively investigated in observational studies; however, the extent of any causal effect remains unclear, making it difficult to evaluate its clinical relevance. Methods and findings A phenome-wide association study (PheWAS) together with a Bayesian analysis of tree-structured phenotypic model (TreeWAS) was performed to examine disease outcomes related to genetically determined serum urate levels in 339,256 unrelated Whit...
Source
#1Xiaomeng Zhang (Edin.: University of Edinburgh)
#2Evropi TheodoratouH-Index: 40
Last.Maria TimofeevaH-Index: 10
view all 13 authors...
Background: Evidence from observational studies suggests a protective role for physical activity (PA) against colorectal cancer (CRC) risk. However, it has yet to be established a causal relationship. We conducted a two-sample Mendelian randomisation (MR) study to examine causality between physical activity and CRC risk. Methods: We used common genetic variants associated with self-reported and accelerometer-based physical activity as instrumental variables (IVs) in this MR study. The IVs were d...
Source
#1Xiangrui Meng (Edin.: University of Edinburgh)H-Index: 5
#2Xue Li (Edin.: University of Edinburgh)H-Index: 8
Last.Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 40
view all 17 authors...
1 CitationsSource
#1Yazhou He (Edin.: University of Edinburgh)H-Index: 3
#2Maria Timofeeva (Edin.: University of Edinburgh)H-Index: 10
Last.Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 7
view all 11 authors...
Background: Germline genetic variants may influence pathways of tumor progression common to multiple cancer types. Here, we investigated the association between survival after colorectal cancer (CRC) diagnosis and 128 common genetic variants previously associated with prognosis in genome-wide association studies (GWAS) in different cancer types. Methods: We studied survival outcomes in a large well-documented, prospective, population-based cohort (5,675 CRC patients) with up to 20 years follow-u...
Source
#1Yazhou He (Edin.: University of Edinburgh)H-Index: 3
#2Yuhan Ong (Western General Hospital)
Last.Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 7
view all 11 authors...
Abstract Prediction models allow accurate estimate of individualized prognosis. Increasing numbers of models on survival of CRC patients with surgical resection are being published. However, their performance and potential clinical utility have been unclear. A systematic search in MEDLINE and Embase databases (until 9th April 2018) was performed. Original model development studies and external validation studies predicting any survival outcomes from CRC (follow-up ≥1 year after surgery) were inc...
Source
#1Xue Li (Edin.: University of Edinburgh)H-Index: 8
#2Xiangrui Meng (Edin.: University of Edinburgh)H-Index: 5
Last.Evropi Theodoratou (Edin.: University of Edinburgh)H-Index: 40
view all 15 authors...
IntroductionThe role of serum urate level has been extensively investigated in observational studies. However, the extent of any causal effect remains unclear, making it difficult to evaluate its clinical relevance.nnObjectivesTo explore any causal or pleiotropic association between serum urate level and a broad spectrum of disease outcomes.nnMethodsPhenome-wide association study (PheWAS) together with a Bayesian analysis of tree-structured phenotypic models (TreeWAS) was performed to examine di...
Source
#1Ting Shi (Edin.: University of Edinburgh)H-Index: 5
#2Angeline Denouel (Sanofi Pasteur)H-Index: 1
Last.Resceu InvestigatorsH-Index: 1
view all 43 authors...
3 CitationsSource
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