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Xueshi Huang
Northeastern University
55Publications
8H-index
214Citations
Publications 58
Newest
#1Qingyin Liu (NU: Northeastern University)
#2Yu Mu (NU: Northeastern University)H-Index: 7
Last.Xueshi Huang (NU: Northeastern University)H-Index: 8
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Abstract A concise total synthesis of an exceedingly potent anti-inflammatory agent violacin A as well as the preparation of thirty analogues of this lead from commercially available orcinol are described. Highlights of our synthetic efforts involve Friedel-Crafts acylation, the regioselective etherification and esterification of phenolic hydroxyl groups, and Baker-Venkatamaran rearrangement to form basic skeleton of violacin A. The deprotection reaction with Pd-catalytic was involved to avoid t...
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#1Wen Xu (NU: Northeastern University)
#2Lu Zhang (URI: University of Rhode Island)H-Index: 2
Last.Liya Li (NU: Northeastern University)H-Index: 6
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Four new barringtogenol C-type triterpenoid saponins, namely acerplatanosides A – D (1–4), along with 22 known compounds (5–26), were isolated from the stem bark of Norway maple (Acer platanoides). Their structures were elucidated on the basis of comprehensive spectroscopic analyses and chemical hydrolysis. This is the first report of triterpenoid saponins isolated from Norway maple. Compounds 1, 3, and 4 showed cytotoxicity against 4 human cancer cell lines with IC50 values ranging from 9.4 to ...
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#1Peipei Guan (NU: Northeastern University)H-Index: 3
#2Xingbo Wang (NU: Northeastern University)H-Index: 3
Last.Cheng-Lin Jiang (Yunnan University)H-Index: 31
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Abstract Three pyrrol-2-aldehyde derivatives, including one new compound, jiangrine G (JG), two known compounds, jiangrine A (JA), and pyrrolezanthine (PZ), were isolated from the fermentation broth of Jiangella alba associated with a traditional Chinese medicinal plant Maytenus austroyunnanensis. The structure of jiangrine G was elucidated by a detailed spectroscopic data analysis including data from CD spectra. The anti-inflammatory activities assay demonstrated that JG and JA suppressed the p...
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#1Yu Mu (NU: Northeastern University)H-Index: 7
#2Xiuyang Yu (NU: Northeastern University)
Last.Xueshi Huang (NU: Northeastern University)H-Index: 8
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#1Xiaoxiao Gao (NU: Northeastern University)H-Index: 2
#2Hongzhi Yao (NU: Northeastern University)
Last.Cheng-Lin Jiang (Yunnan University)H-Index: 31
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Abstract Spectinabilin (1), spectinabilin derivative (2), and a new analogue, 2-demethyl-spectinabilin (3) were isolated from the fermentation broth of a soil-borne Streptomyces spectabilis strain. The structure of the new compound was elucidated by a detailed spectroscopic data analysis including data from CD spectra. Spectinabilin (1) demonstrated cytotoxicity against five human cancer cell lines, with IC50 values ranging from 18.7 ± 3.1 to 34.6 ± 4.7 μM, while derivatives 2 and 3 showed weak ...
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#1Xiao Chen (MOE: Chinese Ministry of Education)
#2Lin-Fang Hu (MOE: Chinese Ministry of Education)
Last.Yiqing Li (MOE: Chinese Ministry of Education)H-Index: 1
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ABSTRACT:Three new phenazine metabolites strepphenazine A–C (1–3), along with a known compound baraphenazine E 4 were isolated from the culture broth of a Streptomyces strain YIM PH20095. The structures were elucidated based on the spectral data. Compounds 1–4 showed different antifungal activity against Fusarium oxysporum, Plectosphaerella cucumerina, Alternaria panax, and Phoma herbarum, which caused root-rot disease of Panax notoginseng with minimal inhibitory concentrations (MICs) of 16-64 μ...
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#1Yuanyuan Li (NU: Northeastern University)H-Index: 4
#2Dongli Li (Wuyi University)
Last.Liya Li (NU: Northeastern University)H-Index: 6
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Reactive oxygen species and subsequent oxidative stress are reported to play important roles in chronic metabolic diseases. Plant-derived polyphenols, especially food-derived phenolics, have attracted a lot of attention due to their potential usage against oxidative stress-related diseases. The leaf of Psidium guajava (known as guava) is regarded as a good resource of polyphenols and its products are commercially available in Japan as functional foods against multiple chronic metabolism disorder...
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#1Gui-Ding Li (NU: Northeastern University)H-Index: 2
#2Yi Jiang (Yunnan University)H-Index: 14
Last.Cheng-Lin Jiang (Yunnan University)H-Index: 31
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A yellow, Gram-stain-negative, aerobic, non-gliding, non-spore-forming, rod-shaped strain, designated YIM 102600T, was isolated from the faeces of Macaca mulatta dwelling in the Yunnan Wild Animal Park, Yunnan Province, South-West PR China. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain YIM 102600T was a member of the genus Flavobacterium , and closely related to Flavobacterium qiangtangense F3T (96.9 % similarity) and Flavobacterium noncentrifugens R-HLS-17T (96.0 % s...
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#1Guiding Li (Yunnan University)H-Index: 3
#2Xiu Chen (Yunnan University)H-Index: 5
Last.Cheng-Lin Jiang (Yunnan University)H-Index: 31
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Strains YIM 102796T and YIM 102701-2T were isolated from the feces of Macaca mulatta and Hylobates hoolock, respectively, living in the Yunnan Wild Animal Park, Yunnan province of China. The two strains were Gram-stain-negative, non-gliding, produced flexirubin pigments, non-flagellated and aerobic bacteria. The 16S rRNA gene-based phylogenetic analysis indicate that both YIM 102796T and YIM 102701-2T are members of the genus Flavobacterium, closely related to F. ummariense DS-12T (95.9% similar...
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#1Jialin Xu (NU: Northeastern University)H-Index: 4
#2Tingting Liu (NU: Northeastern University)H-Index: 3
Last.Liya Li (NU: Northeastern University)H-Index: 6
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3 CitationsSource
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