Sin Gon Kim
Korea University
EndocrinologyType 2 diabetesMetabolic syndromeDiabetes mellitusMedicine
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Publications 205
#1Moon-Kyu Lee (SMC: Samsung Medical Center)H-Index: 30
#2Sin Gon Kim (KU: Korea University)H-Index: 35
Last. Bong Soo Cha (Yonsei University)H-Index: 39
view all 13 authors...
Abstract Aim MLR-1023, called Tolimidone when evaluated unsuccessfully by Pfizer for gastric ulcer disease, has been repurposed as a novel oral insulin sensitizer with its effects mediated by selective activation of Lyn kinase. We aimed to evaluate the optimal dose, efficacy and safety of MLR-1023 in patients with type 2 diabetes. Methods Type 2 diabetes patients (18–75 years) on diet/exercise therapy were randomized and double-blinded to receive MLR-1023 (100-mg or 200-mg, once-daily [qd] or tw...
#1Y Kim (Pfizer)H-Index: 3
#2In-Kyung Jeong (Kyung Hee University)H-Index: 14
Last. Doo Man Kim (Sacred Heart Hospital)H-Index: 9
view all 11 authors...
#1Ji Hee Yu (KU: Korea University)H-Index: 7
#2Kyungdo Han (Catholic University of Korea)H-Index: 21
Last. Nan-Hui Kim (KU: Korea University)H-Index: 40
view all 13 authors...
#1So-hyeon HongH-Index: 1
#2Soon Young HwangH-Index: 17
Last. Hye Jin YooH-Index: 33
view all 12 authors...
#1Kyeong Jin Kim (KU: Korea University)H-Index: 5
#2Sujung Jang (KU: Korea University)
Last. Sin Gon Kim (KU: Korea University)H-Index: 35
view all 14 authors...
#1Kyoung Jin Kim (KU: Korea University)H-Index: 1
#2Jimi Choi (KU: Korea University)H-Index: 1
Last. Nam Hoon Kim (KU: Korea University)H-Index: 10
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To determine the impact of dipeptidyl peptidase-4 inhibitor (DPP4i) on the risk of major cardiocerebrovascular and renal outcomes compared with sulfonylurea (SU) combined with metformin in patients with type 2 diabetes from a population-based cohort. From a nationwide cohort in Korea (2008–2013), 23,674 patients with type 2 diabetes treated with DPP4i plus metformin or SU plus metformin were selected and matched by propensity score. Composite cardiocerebrovascular events including incident ische...
1 CitationsSource
#1Jingi Bae (KU: Korea University)H-Index: 15
#1Jae Hyun Bae (KU: Korea University)H-Index: 7
Last. Nam Hoon Kim (KU: Korea University)H-Index: 10
view all 6 authors...
This study was conducted to investigate the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on individual renal outcomes in patients with type 2 diabetes. We searched MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials from inception to September 2017 to identify randomized controlled trials comparing SGLT2 inhibitors with placebo or antidiabetic drugs and reporting any renal outcomes in patients with type 2 diabetes. Additionally, we identified 4 articles which ...
1 CitationsSource
#1Chung Gyo Seo (KU: Korea University)
#2Kyoung Jin Kim (KU: Korea University)H-Index: 1
Last. Kyeong Jin Kim (KU: Korea University)H-Index: 5
view all 8 authors...
Hypothyroidism, one of the prevalent endocrine disorders worldwide, has a broad spectrum of clinical manifestations, from an asymptomatic condition to myxedema coma. Although the majority of patients with hypothyroidism have minor clinical symptoms, which are recovered with levothyroxine treatment, some patients occasionally do experience fatal complications. Here we report, for the first time, the case of a patient who had hypothyroidism with simultaneous occurrence of rhabdomyolysis with acute...
#1Jung A. Kim (KU: Korea University)H-Index: 1
#2Eun Roh (KU: Korea University)H-Index: 10
Last. Kyung Mook Choi (KU: Korea University)H-Index: 47
view all 11 authors...
Abstract Background Sclerostin is an osteocyte-derived circulating protein that inhibits the Wnt/β-catenin signaling pathway. The Wnt signaling pathway plays an important role in bone and dysregulation of the Wnt signaling pathway results in insulin resistance, inflammation, and metabolic disturbance. The aim of our study was to investigate the implication of sclerostin in low muscle mass in healthy subjects. Methods The cross-sectional study analyzed 240 healthy non-diabetic subjects from the K...
1 CitationsSource