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Megan M. Campbell
University of Cape Town
20Publications
6H-index
98Citations
Publications 20
Newest
#1Joseph Millum (NIH: National Institutes of Health)H-Index: 11
#2Megan M. Campbell (UCT: University of Cape Town)H-Index: 6
Last.Quarraisha Abdool Karim (UKZN: University of KwaZulu-Natal)H-Index: 36
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Background It is critically important to conduct research on stigmatized conditions, to include marginalized groups that experience stigma, and to develop interventions to reduce stigma. However, such research is ethically challenging. Though superficial reference is frequently made to these widely acknowledged challenges, few publications have focused on ethical issues in research on stigmatized groups or conditions. In fact, a brief literature review found only two such publications.
#1Camillia Kong (Birkbeck, University of London)
#2Mehret Efrem (University of Oxford)
Last.Megan M. Campbell (UCT: University of Cape Town)H-Index: 6
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Informed consent procedures for participation in psychiatric genomics research among individuals with mental disorder and intellectual disability can often be unclear, particularly because the underlying ethos guiding consent tools reflects a core ethical tension between safeguarding and inclusion. This tension reflects important debates around the function of consent tools, as well as the contested legitimacy of decision-making capacity thresholds to screen potentially vulnerable participants. ...
#2Dickens Akena (College of Health Sciences, Bahrain)H-Index: 13
Last.Victoria de MenilH-Index: 5
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Introduction Schizophrenia and bipolar disorder account for a large proportion of the global burden of disease. Despite their enormous impact, little is known about their pathophysiology. Given the high heritability of schizophrenia and bipolar disorder, unbiased genetic studies offer the opportunity to gain insight into their neurobiology. However, advances in understanding the genetic architecture of schizophrenia and bipolar disorder have been based almost exclusively on subjects of Northern ...
#1Megan M. Campbell (UCT: University of Cape Town)H-Index: 6
#2Jantina de Vries (UCT: University of Cape Town)H-Index: 17
Last.Stephanus Van Wyk (Walter Sisulu University)H-Index: 1
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Cell line immortalisation is a growing component of African genomics research and biobanking. However, little is known about the factors influencing consent to cell line creation and immortalisation in African research settings. We contribute to addressing this gap by exploring three questions in a sample of Xhosa participants recruited for a South African psychiatric genomics study: First, what proportion of participants consented to cell line storage? Second, what were predictors of this conse...
#1Megan M. Campbell (UCT: University of Cape Town)H-Index: 6
#2Goodman Sibeko (UCT: University of Cape Town)H-Index: 5
Last.Dan J. Stein (UCT: University of Cape Town)H-Index: 104
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Background Although the relationship between cultural beliefs and schizophrenia has received some attention, relatively little work has emerged from African contexts. In this study we draw from a sample of South African Xhosa people with schizophrenia, exploring their cultural beliefs and explanations of illness. The purpose of the article is to examine the relationship between this cultural context and the content of delusions.
#1Megan M. Campbell (UCT: University of Cape Town)H-Index: 6
#2Ezra Susser (Columbia University)H-Index: 62
Last.Dan J. Stein (UCT: University of Cape Town)H-Index: 104
view all 10 authors...
Obtaining informed consent is a great challenge in global health research. There is a need for tools that can screen for and improve potential research participants’ understanding of the research study at the time of recruitment. Limited empirical research has been conducted in low and middle income countries, evaluating informed consent processes in genomics research. We sought to investigate the quality of informed consent obtained in a South African psychiatric genomics study. A Xhosa languag...
#1Paulina TindanaH-Index: 16
#2Megan M. CampbellH-Index: 6
Last.Dorcas KamuyaH-Index: 12
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Historically, community engagement (CE) in research has been implemented in the fields of public health, education and agricultural development. In recent years, international discussions on the ethical and practical goals of CE have been extended to human genomic research and biobanking, particularly in the African context. While there is some consensus on the goals and value of CE generally, questions remain about the effectiveness of CE practices and how to evaluate this. Under the auspices o...
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