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Yu-Tzu Lin
National Taiwan University
19Publications
8H-index
102Citations
Publications 19
Newest
#1Yu-Ting Wang (NTU: National Taiwan University)
#2Yu-Tzu Lin (NTU: National Taiwan University)H-Index: 8
Last.Lee-Jene Teng (NTU: National Taiwan University)H-Index: 43
view all 8 authors...
Abstract We investigated antibiotic resistance of staphylococci isolated from 1128 samples of high-circulating RTE foods in Taiwan. A total of 111 Staphylococcus aureus and 709 coagulase-negative staphylococci (CoNS) comprising 23 species were isolated. The prevalence of S. aureus differed in various category of RTE foods, highest in fresh-cut fruits/vegetables (20.5%) and lowest in low-water activity (LWA) foods (0.7%). The overall staphylococcal contamination was highest in fresh-cut fruits/ve...
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#1Chih-Cheng LaiH-Index: 23
#2Yi-Tsung Lin (Taipei Veterans General Hospital)H-Index: 21
Last.Po-Ren Hsueh (NTU: National Taiwan University)H-Index: 72
view all 13 authors...
ABSTRACT This nationwide surveillance was conducted in 2017 to investigate the prevalence and clinical characteristics of patients with bacteraemia due to mcr-1 -harbouring Enterobacteriaceae as well as the presence of mcr-1 -harbouring Escherichia coli in pigs. Non-duplicate, consecutive bacterial isolates were collected from patients treated at 16 hospitals in Taiwan. All E. coli ( n = 686) and Klebsiella pneumoniae ( n = 673) isolates from humans were obtained from patients with bacteraemia; ...
1 CitationsSource
#1Tsai-Wen Wan (NTU: National Taiwan University)H-Index: 3
#2Yu-Tzu Lin (NTU: National Taiwan University)H-Index: 8
Last.Lee-Jene Teng (NTU: National Taiwan University)H-Index: 43
view all 7 authors...
Antimicrobial resistance in Staphylococcus aureus is a major problem and the acquisition of resistance genes may occur by horizontal gene transfer (HGT). The transposon, an important means of HGT, is recognized as a mobile genetic element that can integrate in plasmids, replicate and transfer to other strains. We have previously reported a novel structure of the Enterococcus faecium -originated Tn 1546 - ermB element in S. aureus . The emergence of the Tn 1546 -like element is an emerging proble...
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#1Yu-Tzu Lin (NTU: National Taiwan University)H-Index: 8
#2Wei-Chun Hung (KMU: Kaohsiung Medical University)H-Index: 13
Last.Lee-Jene Teng (NTU: National Taiwan University)H-Index: 43
view all 7 authors...
Abstract The fusidic acid (FUS) resistance determinants fusB , fusC , fusD and fusF in coagulase-negative staphylococci (CoNS) clinical isolates were examined. Among 208 FUS-resistant isolates, the fusB gene was the most common resistance determinant in each species, except in Staphylococcus hominis subsp. hominis or in species carrying intrinsic fusD or fusF . In S. hominis subsp. hominis , the fusC gene was the major determinant responsible for FUS resistance. To understand the genetic context...
1 CitationsSource
#1Tsai-Wen Wan (NTU: National Taiwan University)H-Index: 3
#2Wataru Higuchi (Niigata University)H-Index: 22
Last.Tatsuo Yamamoto (Niigata University)H-Index: 24
view all 14 authors...
A bacterial insertion sequence (IS) is a mobile DNA sequence carrying only the transposase gene (tnp) that acts as a mutator to disrupt genes, alter gene expressions, and cause genomic rearrangements. “Canonical” ISs have historically been characterized by their terminal inverted repeats (IRs), which may form a stem-loop structure, and duplications of a short (non-IR) target sequence at both ends, called target site duplications (TSDs). The IS distributions and virulence potentials of Staphyloco...
3 CitationsSource
#1Fon Yih Tsuang (South Korean Ministry for Health, Welfare and Family Affairs)H-Index: 6
#2Yu-Tzu LinH-Index: 8
Last.Jui-Chang TsaiH-Index: 25
view all 5 authors...
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#1Sung-Pin Tseng (KMU: Kaohsiung Medical University)H-Index: 17
#2Wei-Chun Hung (KMU: Kaohsiung Medical University)H-Index: 13
Last.Jui-Chang Tsai (NTU: National Taiwan University)H-Index: 25
view all 9 authors...
Abstract Background/objectives Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was recognized as a leading pathogen and has been shown to be genetically different from the health care-associated MRSA (HA-MRSA). Photodynamic therapy (PDT) is considered a potential alternative method for the treatment of resistant bacterial infections, but the effect of PDT on CA-MRSA is unknown. The purpose of this study was to compare the bactericidal effects of toluidine blue O (TBO) ...
10 CitationsSource
#1Tsai-Wen Wan (NTU: National Taiwan University)H-Index: 3
#2Wei-Chun Hung (KMU: Kaohsiung Medical University)H-Index: 13
Last.Lee-Jene Teng (NTU: National Taiwan University)H-Index: 43
view all 8 authors...
ABSTRACT We determined the resistance determinants in 274 erythromycin-resistant methicillin-susceptible Staphylococcus aureus (MSSA) isolates during a 13-year period, 2000 to 2012. The resistance phenotypes, inducible macrolide-lincosamide-streptogramin (iMLS), constitutive MLS (cMLS), and macrolide-streptogramin (MS) resistance phenotypes, were examined by a double-disk diffusion D test. The ermB gene was more frequent (35%; 97/274) than ermC (27%; 75/274) or ermA (21%; 58/274). All 97 ermB -p...
4 CitationsSource
#1Wei-Chun Hung (KMU: Kaohsiung Medical University)H-Index: 13
#2Tsai-Wen Wan (NTU: National Taiwan University)H-Index: 3
Last.Lee-Jene Teng (NTU: National Taiwan University)H-Index: 43
view all 8 authors...
Clonal complex 59 (CC59) Staphylococcus aureus in Taiwan includes both methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). As the most prominent community-associated MRSA (CA-MRSA) in Taiwan, CC59 has two major clones characterized as PVL-negative SCCmec IV (carrying the staphylococcal cassette chromosome mec IV but Panton-Valentine leukocidin-negative) and PVL-positive SCCmec V (5C2&5). We investigated the drug resistance, phylogeny and the distribution and sequ...
2 CitationsSource
#1Hsiao-Jan Chen (NTU: National Taiwan University)H-Index: 10
#2Yu-Tzu Lin (NTU: National Taiwan University)H-Index: 8
Last.Lee-Jene Teng (NTU: National Taiwan University)H-Index: 43
view all 6 authors...
ABSTRACT We analyzed the staphylococcal cassette chromosome mec (SCC mec ) types of 143 fusidic acid- and methicillin-resistant Staphylococcus epidermidis isolates. The most frequent SCC mec type was SCC mec III/SCC Hg (53%), followed by SCC mec IV (29%). Clonal spreading of SCC mec III/SCC Hg strains contributed to the increased prevalence of SCC mec III. A novel non- mec SCC structure, SCC 7684 , adjacent to SCC mec III, which carries a new ccrC allotype ( ccrC3 allele 1) and contains heavy me...
3 CitationsSource
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