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Yamin Wang
Drug carrierSpecific surface areaNanoparticleDrug deliveryAcrylic acid
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#1Xu Zhang (Henan University)H-Index: 4
#2Yamin WangH-Index: 1
Last. Lei Sun (Henan University)H-Index: 11
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Abstract In this work, pH-sensitive “dual-switch” porous silica (pSiO2) nanoparticles (NPs) were constructed for drug delivery. Poly(acrylic acid) (PAA) was grafting onto the internal and external surfaces of amino groups functionalized porous silica (pSiO2-NH2) NPs by the amidation between the amino groups and the carboxyl groups of PAA for pH triggered drug release. The resultant pSiO2/PAA NPs have an average diameter of 50–60 nm and high specific surface area (914 m2·g− 1). To improve the loa...
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