Malgorzata Gajewska
Instituto Superior Técnico
Publications 2
#1Marta Martins (UCD: University College Dublin)H-Index: 36
#2Pedro V. Baptista (NOVA: Universidade Nova de Lisboa)H-Index: 33
Last.Alexandra R. Fernandes (NOVA: Universidade Nova de Lisboa)H-Index: 26
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Identification of novel molecules that can selectively inhibit the growth of tumor cells, avoid causing side effects to patients and/or intrinsic or acquired resistance, usually associated with common chemotherapeutic agents, is of utmost importance. Organometallic compounds have gained importance in oncologic chemotherapy, such as organotin(IV) complexes. In this study, we assessed the anti-tumor activity of the cyclic trinuclear organotin(IV) complex with an aromatic oximehydroxamic acid group...
8 CitationsSource
#1Malgorzata Gajewska (IST: Instituto Superior Técnico)H-Index: 2
#2Konstantin V. Luzyanin (IST: Instituto Superior Técnico)H-Index: 23
Last.Armando J. L. Pombeiro (IST: Instituto Superior Técnico)H-Index: 59
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The reactions between equimolar amounts of R2SnO (R = Me 1, nBu 2) and N,2-dihydroxy-5-[N-hydroxyethanimidoyl]benzamide (H2L) under solvent reflux conditions (in toluene for 1 and methanol for 2) for ca. 4 h led to the formation of the trinuclear tin complexes [R2Sn(L)]3 (R = Me 3, nBu 4) isolated as colourless crystalline solids in ca. 85 % yield, which were characterized by IR, 1H, 13C and 119Sn NMR spectroscopy, elemental analysis and (for 4) by X-ray diffraction. The trinuclear Sn core is st...
17 CitationsSource