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Md. Tanvir Kabir
BRAC University
ChemistryAntioxidantBiochemistryBiologyPharmacology
21Publications
4H-index
46Citations
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Publications 34
Newest
#1Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
#2Abdullah Al Mamun (SEU: Southeast University)
Last. Mohamed M. Abdel-Daim (KSU: King Saud University)H-Index: 24
view all 10 authors...
Neuropathic pain (NP) is the result of the irregular processing in the central or peripheral nervous system, which is generally caused by neuronal injury. The management of NP represents a great challenge owing to its heterogeneous profile and significant undesirable side effect of the frequently prescribed psychoactive agents including benzodiazepines (BDZ). Currently, several established drugs including antidepressants, anticonvulsants, topical lidocaine, and opioids are used to treat NP, but ...
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Abstract Amyloid beta (Aβ) is an intricate molecule that interacts with several biomolecules and/or produces insoluble assemblies and eventually the nonphysiological depositions of its alternate with normal neuronal conditions leading to Alzheimer’s disease (AD). Aβ is formed through the proteolytic cleavage of an integral type I membrane protein amyloid precursor protein (APP). Significant efforts are being made to explore the exact role of Aβ in AD pathogenesis. It is believed that the deposit...
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#1Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
#1Sahab Uddin (SEU: Southeast University)H-Index: 2
Last. Ghulam Md Ashraf (KAU: King Abdulaziz University)H-Index: 16
view all 9 authors...
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is marked by cognitive dysfunctions and existence of neuropathological hallmarks such as amyloid plaques, and neurofibrillary tangles. It has been observed that a persistent immune response in the brain has appeared as another neuropathological hallmark in AD. The persistent activation of the microglia, the brain's resident macrophages, and other immune cells has been shown to aggravate both tau and amyloid pathology and may c...
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#1Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
#2Md. Ataur Rahman (KIST: Korea Institute of Science and Technology)H-Index: 1
Last. Ghulam Md Ashraf (KAU: King Abdulaziz University)H-Index: 16
view all 10 authors...
Age-related cognitive failure is a main devastating incident affecting even healthy people. Alzheimer's disease (AD) is the utmost common form of dementia among the geriatric community. In the pathogenesis of AD, cerebrovascular dysfunction is revealed before the beginning of the cognitive decline. Mounting proof shows a precarious impact of cerebrovascular dysregulation in the development of AD pathology. Recent studies document that the mammalian target of rapamycin (mTOR) acts as a crucial ef...
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#1Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
#2Devesh Tewari (LPU: Lovely Professional University)H-Index: 8
Last. Ghulam Md Ashraf (KAU: King Abdulaziz University)H-Index: 16
view all 9 authors...
: Alzheimer's disease (AD) is a progressive neurodegenerative disease involving aggregation of misfolded proteins inside the neuron causing prolonged cellular stress. The neuropathological hallmarks of AD include the formation of senile plaques and neurofibrillary tangles in specific brain regions that lead to synaptic loss and neuronal death. The exact mechanism of neuron dysfunction in AD remains obscure. In recent years, endoplasmic reticulum (ER) dysfunction has been implicated in neuronal d...
1 CitationsSource
#1Md. Tanvir Kabir (BRACU: BRAC University)H-Index: 4
#2Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
Last. Mohamed M. Abdel-Daim (KSU: King Saud University)H-Index: 24
view all 10 authors...
Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Even though the number of AD patients is rapidly growing, there is no effective treatment for this neurodegenerative disorder. At present, implementation of effective treatment approaches for AD is vital to meet clinical needs. In AD research, priorities concern the development of disease-modifying therapeutic agents to be used in the early phases of AD and the optimization of the symptomatic treatments predominantly dedicated ...
4 CitationsSource
#1Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
#2Md. Tanvir Kabir (BRACU: BRAC University)H-Index: 4
Last. Mohamed M. Abdel-Daim (KSU: King Saud University)H-Index: 24
view all 9 authors...
Alzheimer’s disease (AD) is the most common cause of dementia among older people, and the prevalence of this disease is estimated to rise quickly in the upcoming years. Unfortunately, almost all of the drug candidates tested for AD until now have failed to exhibit any efficacy. Henceforth, there is an increased necessity to avert and/or slow down the advancement of AD. It is known that one of the major pathological characteristics of AD is the presence of senile plaques (SPs) in the brain. These...
4 CitationsSource
#1Md. Sahab UddinH-Index: 9
#1Sahab Uddin (SEU: Southeast University)H-Index: 2
Last. Ghulam Md AshrafH-Index: 16
view all 7 authors...
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases characterized by the formation of extracellular amyloid beta (Abeta) plaques and intracellular neurofibrillary tangles (NFTs). Growing evidence suggested that there is an association between neuronal dysfunction and neuroinflammation (NI) in AD, coordinated by the chronic activation of astrocytes and microglial cells along with the subsequent excessive generation of the proinflammatory molecule. Therefore, a better ...
4 CitationsSource
#1Md. Tanvir Kabir (BRACU: BRAC University)H-Index: 4
#2Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
Last. Asma PerveenH-Index: 6
view all 6 authors...
BACKGROUND: Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the characteristics of this devastating disorder include the progressive and disabling deficits in the cognitive functions including reasoning, attention, judgment, comprehension, memory, and language. OBJECTIVE: In this article, we have focused on the recent progress that has been achieved in the development of an effective AD vaccine. SUMMARY: Currently, available treatment options of AD are limited to deliver sho...
2 CitationsSource
#1Md. Sahab Uddin (SEU: Southeast University)H-Index: 9
#1Sahab Uddin (SEU: Southeast University)H-Index: 2
Last. Ghulam Md Ashraf (KAU: King Abdulaziz University)H-Index: 16
view all 8 authors...
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the most common type of dementia. Along with progressive cognitive impairment, dysfunction of the circadian rhythms also play a pivotal role in the progression of AD. A mutual relationship among circadian rhythms, sleep, and AD has been well-recommended. The etiopathogenesis of the disturbances of the circadian system and AD share some general features that also unlock the outlook of observing them as a mutually ...
7 CitationsSource
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