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Andrew St. Martin
Center for International Blood and Marrow Transplant Research
ImmunologyHazard ratioCyclophosphamideTransplantationMedicine
14Publications
5H-index
155Citations
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Publications 18
Newest
#1Vincent T. Ho (Harvard University)H-Index: 71
#2Andrew St. Martin (Center for International Blood and Marrow Transplant Research)H-Index: 5
Last. Wael Saber (Center for International Blood and Marrow Transplant Research)H-Index: 28
view all 9 authors...
Abstract Gemtuzumab ozogamicin (GO) therapy prior to allogeneic hematopoietic cell transplantation (alloHCT) has been historically associated with an increased risk of hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) in patients with acute myeloid leukemia (AML). The current analysis examined VOD/SOS risk and outcomes in a cohort of patients who in recent years reported to the Center for International Blood & Marrow Transplant Research. Adults with AML who had GO exposure...
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#1Giancarlo Fatobene (USP: University of São Paulo)H-Index: 1
#2Vanderson Rocha (USP: University of São Paulo)H-Index: 67
Last. Alida DominiettoH-Index: 24
view all 27 authors...
PURPOSETo compare the outcomes of patients with Hodgkin or non-Hodgkin lymphoma undergoing nonmyeloablative haploidentical or unrelated cord blood (UCB) hematopoietic cell transplantation.PATIENTS ...
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#1Miguel-Angel Perales (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 43
#2Benjamin Tomlinson (Case Western Reserve University)H-Index: 3
Last. Mary Eapen (MCW: Medical College of Wisconsin)H-Index: 51
view all 17 authors...
We sought to study whether survival after haplo-identical transplantation is comparable to that after matched unrelated donor transplantation for 822 patients aged 50-75 years with acute myeloid leukemia in first or second complete remission. One hundred and ninety-two patients received grafts from haplo-identical donors (sibling 25%; offspring 75%) and 631 patients from matched unrelated donors aged 18-40 years. Patient and disease characteristics of the two groups were similar except recipient...
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#1Michael R. GrunwaldH-Index: 11
#2Mei-Jie Zhang (MCW: Medical College of Wisconsin)H-Index: 63
Last. Mary Eapen (MCW: Medical College of Wisconsin)H-Index: 51
view all 22 authors...
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#1Stefan O. Ciurea (University of Texas MD Anderson Cancer Center)H-Index: 30
Last. Marcelo C. Pasquini (MCW: Medical College of Wisconsin)H-Index: 42
view all 13 authors...
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#1Scott R. Solomon (Northside Hospital)H-Index: 22
#2Andrew St. Martin (Center for International Blood and Marrow Transplant Research)H-Index: 5
Last. Mary Eapen (Center for International Blood and Marrow Transplant Research)H-Index: 51
view all 28 authors...
In the absence of prospective studies that examine the effect of conditioning regimen intensity after T-cell–replete haploidentical transplant for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and myelodysplastic syndrome (MDS), a retrospective cohort analysis was performed. Of the 1325 eligible patients (AML, n = 818; ALL, n = 286; and MDS, n = 221), 526 patients received a myeloablative regimen and 799 received a reduced-intensity regimen. Graft-versus-host disease prophyla...
2 CitationsSource
#1Daniel A. Keesler (Center for International Blood and Marrow Transplant Research)H-Index: 4
#2Andrew St. Martin (Center for International Blood and Marrow Transplant Research)H-Index: 5
Last. Mary Eapen (Center for International Blood and Marrow Transplant Research)H-Index: 51
view all 6 authors...
Abstract Graft-versus-host disease (GVHD) rates are higher after unrelated donor transplantation; thus, we examined whether there would be differences in transplant outcomes by graft type in children and adolescents with acute leukemia. The primary endpoint was overall survival. We studied 872 patients
2 CitationsSource
#1Scott R. SolomonH-Index: 22
#2Andrew St. Martin (MCW: Medical College of Wisconsin)H-Index: 5
Last. Mary Eapen (MCW: Medical College of Wisconsin)H-Index: 51
view all 28 authors...
The significance of conditioning regimen intensity on the outcomes of T-cell replete HLA-haploidentical transplants is not known. This study compared outcomes of commonly used myeloablative (MAC) to reduced intensity (RIC) conditioning regimens in 1325 such transplants (AML; n=818; ALL; n=286 and MDS; n=221) in the US between 2008 and 2016. The median age of the study population was 54 years (18 - 70). Most patients (80%) with AML and ALL were in first or subsequent remission; 83% of those with ...
1 CitationsSource
#1Tara M. Robinson (Johns Hopkins University)H-Index: 3
#2Ephraim J. Fuchs (Johns Hopkins University)H-Index: 47
Last. Arnon Nagler (Sheba Medical Center)H-Index: 93
view all 23 authors...
We sought to identify whether posttransplantation cyclophosphamide (PT-Cy) reduces or eliminates the detrimental impact of HLA mismatching on outcomes of HLA-haploidentical related donor transplantation for acute leukemia. Data from 2143 donor-recipient pairs (n = 218 haploidentical sibling; n = 218 offspring; n = 1707 HLA-matched sibling) with acute myeloid or lymphoblastic leukemia were studied. All received a calcineurin inhibitor for graft-versus-host disease (GVHD) prophylaxis while high-do...
13 CitationsSource
#1Vincent T. Ho (Harvard University)H-Index: 71
#2Andrew St. Martin (Center for International Blood and Marrow Transplant Research)H-Index: 5
Last. Wael Saber (Center for International Blood and Marrow Transplant Research)H-Index: 28
view all 9 authors...
2 CitationsSource
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