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Weili Zhang
Peking Union Medical College
47Publications
17H-index
874Citations
Publications 47
Newest
Published on Mar 11, 2019in Respiratory Research 3.75
Junsong Gong (Peking Union Medical College), Zujun Chen (Peking Union Medical College)+ 6 AuthorsJia Shi2
Estimated H-index: 2
(Peking Union Medical College)
Background In this study, we aimed to investigate whether and how lncRNA CASC2 was involved in hypoxia-induced pulmonary hypertension (PH)-related vascular remodeling.
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Published on May 9, 2019in Acta Neurologica Scandinavica 3.13
Tao Kong (Peking Union Medical College), Jingzhou Chen14
Estimated H-index: 14
(Peking Union Medical College)
+ 5 AuthorsRutai Hui22
Estimated H-index: 22
(Peking Union Medical College)
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Published on Jul 1, 2019in Biochimica et Biophysica Acta 3.44
Shujun Yang3
Estimated H-index: 3
(Peking Union Medical College),
Jian Li1
Estimated H-index: 1
(Peking Union Medical College)
+ 8 AuthorsBin Lv9
Estimated H-index: 9
(Peking Union Medical College)
Abstract Macrophages exhibit heterogeneity and plasticity and imbalance between pro-inflammatory and anti-inflammatory macrophages plays a critical role in atherosclerosis progression. Telomerase reverse transcriptase (TERT) in macrophages can be activated by nuclear factor-kappa B (NF-κB), but the regulation of telomerase activation on macrophages polarization remains unknown. We previously identified microRNA-216a (miR-216a) to promote inflammation through directly targeting the Smad3/NF-κB pa...
2 Citations Source Cite
Published on May 1, 2019in Journal of Molecular and Cellular Cardiology 5.30
Chenghui Zhou (Peking Union Medical College), Yu Chen (Peking Union Medical College)+ 6 AuthorsJia Shi2
Estimated H-index: 2
(Peking Union Medical College)
Abstract Objective To analyze the effects of miR-455-3p-1 and its possible mechanisms in pulmonary arterial hypertension (PAH). Methods A microarray assay was used to examine the expressed genes between normal and PAH. The expressed genes in PAH was assessed by qRT-PCR. The targeted interaction between miRNAs and FGF7 was confirmed using a dual luciferase reporter assay. A CCK-8 assay and cell count were used to analyze the pulmonary artery smooth muscle cells (PASMCs) activity and proliferation...
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Published on May 1, 2019in Experimental Gerontology 3.22
Rongxia Li (Peking Union Medical College), Xuenan Mi2
Estimated H-index: 2
(Peking Union Medical College)
+ 5 AuthorsWeili Zhang17
Estimated H-index: 17
(Peking Union Medical College)
Abstract The role of angiotensin II (Ang II) in hypertension has been clarified, but recent studies show that aging-associated arterial changes and those with hypertension as well as atherosclerosis may have some common pathogenesis. This study aimed to clarify the effects of Ang II on endothelial senescence by establishing a replicative senescence model of human umbilical vein endothelial cells (HUVECs) in vitro . The population-doubling level (PDL) was calculated, PDL5 and PDL25 respectively r...
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Published on Dec 4, 2018in Clinical and Experimental Hypertension 1.37
Cunjin Wu (Tianjin Medical University), Yibo Wang17
Estimated H-index: 17
(Peking Union Medical College)
+ 3 AuthorsRutai Hui22
Estimated H-index: 22
(Peking Union Medical College)
ABSTRACTThe prevalence and associated risk factors of apparent treatment-resistant hypertension (aTRH) in older people in China is unknown. The aim of this study is to investigate the prevalence of aTRH in older people and describe the characteristics of older patients with aTRH. Using two-stage random clustering sampling, 3774 patients with hypertension aged ≥60–75 years were recruited between July 2012 and December 2015. The patients were divided into two groups: aTRH and non-aTRH groups accor...
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Published on Dec 1, 2018in Scientific Reports 4.12
Jing Li1
Estimated H-index: 1
,
Congrui Feng2
Estimated H-index: 2
(Capital Medical University)
+ 5 AuthorsWeili Zhang17
Estimated H-index: 17
(Peking Union Medical College)
The relationship between telomere length and stroke was inconsistent mostly due to different pathogenesis of subtypes, environment and genetics. We aimed to assess whether leukocyte telomere contributes to stroke in Southern Chinese by investigating a case-control study comprising 543 cases (224 atherothrombotic stroke, 94 hemorrhagic stroke and 225 lacunar infraction) and 616 controls and replicated the investigation in an independent study comprising 773 cases and 875 controls with the same di...
3 Citations Source Cite
Published on May 1, 2018in Journal of Cellular and Molecular Medicine 4.30
Shujun Yang3
Estimated H-index: 3
(Peking Union Medical College),
Xuenan Mi2
Estimated H-index: 2
(Peking Union Medical College)
+ 4 AuthorsWeili Zhang17
Estimated H-index: 17
(Capital Medical University)
5 Citations Source Cite
Published on Jan 1, 2017in Archives of Medical Science 2.34
Wenlong Li4
Estimated H-index: 4
,
Bi Rong Huang1
Estimated H-index: 1
+ 7 AuthorsXiaohan Fan11
Estimated H-index: 11
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