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Laura Gerardino
Catholic University of the Sacred Heart
EndocrinologySurgeryCardiologyDiabetes mellitusMedicine
31Publications
13H-index
433Citations
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Publications 31
Newest
#2Laura GerardinoH-Index: 13
Last. Paolo TondiH-Index: 22
view all 6 authors...
Last. Paolo TondiH-Index: 22
view all 8 authors...
OBJECTIVE: To analyze serum biomarkersofCVDinselectedpatientswithpri- mary axial reflux of great saphenous vein in oneorbothlowerlimbs. PATIENTS AND METHODS:Ninety-sixpatients affected by uncomplicated varicose veins, were enrolled in the study. A unilateral, primary axial refluxingreatsaphenousveinswasdetectedin 54patients(U-CVDgroup)andabilateralonein 42 (B-CVD group). Sixty-five age and sex- matched subjects without venous reflux were enrolled as controls. Mean venous pressure of both lower l...
1 Citations
BACKGROUND: Vascular calcifi - cation and osteoporosis share similar etiopatho - genetic mechanisms. Vitamin K2 deficiency could be responsible of the so called "calcium paradox", that is the lack of calcium in the bone and its storage in the vessel wall. These events may have clinically relevant consequences, such as cardiovascular accidents, and bone fractures. AIM: To review the biological function of vita - min K2 metabolism, the main factors related to its deficiency and the consequent clin...
15 Citations
#1Mario Gaudino (CUA: The Catholic University of America)H-Index: 30
#2Amedeo Anselmi (CUA: The Catholic University of America)H-Index: 14
Last. Paolo Tondi (CUA: The Catholic University of America)H-Index: 22
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Background: We aimed at evaluating the late haemodynamic and functional consequences on the forearm circulation of radial artery removal for coronary artery bypass grafting. Methods: Ten years after surgery we performed basal and stress echo-Doppler evaluation of the forearm circulation, baseline and stress transcutaneous oxymetry and determination of reactive oxygen metabolites in the operated and control arm in 20 asymptomatic patients submitted to radial artery removal. Results: The peak syst...
3 CitationsSource
#1Emidio Scarpellini (CUA: The Catholic University of America)H-Index: 19
#2Alessia Cazzato (CUA: The Catholic University of America)H-Index: 15
Last. Antonio Gasbarrini (CUA: The Catholic University of America)H-Index: 72
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There is a natural feeling between our intestinal flora and the gut. These microorganisms, living in the various tracts of human intestine, may affect the host homeostasis. Some of these bacteria can
17 CitationsSource
#1Roberto Antonio Flore (UCSC: Catholic University of the Sacred Heart)H-Index: 19
#2Laura Gerardino (UCSC: Catholic University of the Sacred Heart)H-Index: 13
Last. Paolo Tondi (UCSC: Catholic University of the Sacred Heart)H-Index: 22
view all 6 authors...
Background Healthy workers who stand for prolonged periods show enhanced production of reactive oxygen species (ROS) in their systemic circulation. Oxidative stress is thought to be a risk factor for chronic venous insufficiency and other systemic diseases. Aim To evaluate the effectiveness of compression stockings in the prevention of oxidative stress at work. Methods ROS and venous pressure of the lower limbs were measured in 55 theatre nurses who stood in the operating theatre for >6 h, 23 in...
15 CitationsSource
#1Laura GerardinoH-Index: 13
#2Pierangelo PapaleoH-Index: 12
Last. Roberto PolaH-Index: 32
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AbstractBlood coagulation factor XIII (FXIII) plays a role in inflammatory processes and a pathogenetic role of inflammation in neurodegenerative disorders has been proposed. FXIIIa subunit was immunohistochemically detected in a subpopulation of reactive microglia in Alzheimer's disease (AD). Aim of the present study is to evaluate whether a common polymorphism of the FXIII gene is associated with sporadic AD. We examined 90 patients affected by sporadic AD and 139 age- and sex-matched controls...
7 CitationsSource
#1Mario GaudinoH-Index: 30
#2Michele Serricchio (CUA: The Catholic University of America)H-Index: 21
Last. Gianfederico PossatiH-Index: 30
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Background Only scant information is available on the chronic consequences of radial artery removal for coronary artery bypass surgery on forearm circulation. Methods Twenty-five patients submitted to radial artery removal for coronary artery bypass were submitted to serial Doppler echocardiographic evaluation of the flow and morphology of the forearm arteries. Results The peak systolic velocity of the ulnar artery of the operated side was significantly higher than that of the control site. The ...
32 CitationsSource
#1Paolo TondiH-Index: 22
#2Laura GerardinoH-Index: 13
Last. Roberto Antonio FloreH-Index: 19
view all 9 authors...
Background. Hemodynamic, hemorheologic, and metabolic changes are main determinants in the genesis of ischemic leg ulcers. Because prostaglandin E1 (alprostadil) could successfully counteract these changes, it has been intravenously used in the treatment of this disease. Objective. The aim of this study was to evaluate the efficacy of alprostadil in the treatment of ischemic ulcers and to compare subcutaneous with intravenous administration. Methods. Eighty patients were enrolled. Twenty-five we...
8 CitationsSource
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