Elodie Laridan
Katholieke Universiteit Leuven
Neutrophil extracellular trapsCardiologyImmunologyThrombusStroke
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Publications 3
#1Elodie Laridan (Katholieke Universiteit Leuven)H-Index: 2
#2Kimberly Martinod (Katholieke Universiteit Leuven)H-Index: 22
Last. Simon F. DeMeyer (Katholieke Universiteit Leuven)H-Index: 22
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Thrombotic complications are still a major health risk worldwide. Our view on the pathophysiology of thrombosis has significantly changed since the discovery of neutrophil extracellular traps (NETs) and their prothrombotic characteristics. Generated by neutrophils that release their decondensed chromatin as a network of extracellular fibers, NETs promote thrombus formation by serving as a scaffold that activates platelets and coagulation. The thrombogenic involvement of NETs has been described i...
5 CitationsSource
#1Elodie Laridan (Katholieke Universiteit Leuven)H-Index: 2
#2Frederik Denorme (Katholieke Universiteit Leuven)H-Index: 10
Last. Simon F. DeMeyer (Katholieke Universiteit Leuven)H-Index: 22
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Objective: Neutrophil extracellular traps (NETs) have been shown to promote thrombus formation. Little is known about the exact composition of thrombi that cause ischemic stroke. In particular no information is yet available on the presence of NETs in cerebral occlusions. Such information is however essential to improve current thrombolytic therapy with t-PA. This study aimed at investigating the presence of neutrophils and more specifically NETs in ischemic stroke thrombi. Methods: Sixty-eight ...
49 CitationsSource
#1Elodie LaridanH-Index: 2
#2Frederik DenormeH-Index: 10
Last. Simon F. DeMeyerH-Index: 22
view all 8 authors...